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Horm Metab Res 1976; 8(3): 212-215
DOI: 10.1055/s-0028-1093662
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© Georg Thieme Verlag KG Stuttgart · New York

Time Sequence of 3',5'-Cyclic AMP Accumulation and Ultrastructural Changes in Dog Thyroid Slices after Acute Stimulation by TSH[*]

P.  Ketelbant-Balasse , J.  Van Sande , P.  Neve , J. E. Dumont
  • Laboratories of Pathology, Electron Microscopy, Experimental Medicine Institut de Recherche Interdisciplinaire, School of Medicine, Free University of Brussels, and Biology Department[**], Euratom, Brussels, Belgium
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Publication History

Publication Date:
23 December 2008 (online)

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Abstract

cAMP accumulation and pseudopod formation have been studied in dog thyroid slices stimulated by thyrotropin. It is shown that the kinetics and concentration effect relationship support the validity of Sutherland's model of hormone action through cAMP for thyrotropin and thyroid secretion.

Key words

cAMP - Dog Thyroid - Thyroid Secretion - TSH

1 Work done with the aid of grants no. 20013 and 20472 of the FRSM and under Contract of the Ministère de la Politique Scientifique within the framework of the Association Euratom - University of Brussels - University of Pisa.

1 Work done with the aid of grants no. 20013 and 20472 of the FRSM and under Contract of the Ministère de la Politique Scientifique within the framework of the Association Euratom - University of Brussels - University of Pisa.

2 Publication n° B10 1140