Horm Metab Res 1976; 8(3): 175-181
DOI: 10.1055/s-0028-1093655
Originals

© Georg Thieme Verlag KG Stuttgart · New York

Studies on the Pituitary "Fettstoffwechselhormon" - VI. Preparation of Two Highly Purified Lipolytic Active Peptides from Hog Pituitary Glands.[*]

M.  Schleyer , K. H. Voigt , E. F. Pfeiffer
  • Department of Endocrinology, Metabolism and Internal Medicine, Center of Internal Medicine and Pediatrics, University of Ulm, Germany
Further Information

Publication History

Publication Date:
23 December 2008 (online)

Abstract

The preparation of two highly purified lipolytically active hog pituitary peptides, called P-LF II C and P-LF II D is described. The two peptides are free of other pituitary hormone activities. In isolated rat and porcine adipose tissue, both fractions are lipolytically much more active than every other lipolytic active pituitary peptide described to date. By fraction P-LF II D, the first pituitary peptide was isolated which has higher lipolytic activity in isolated rat adipose tissue than corticotropin, the lipolytically most active pituitary hormone known so far. On isolated porcine adipose tissue, fraction P-LF II D as well as P-LF II C showed without doubt higher activity than corticotropin.

1 Supported by Deutsche Forschungsgemeinschaft, SFB 87.

1 Supported by Deutsche Forschungsgemeinschaft, SFB 87.