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Horm Metab Res 1976; 8(4): 317-319
DOI: 10.1055/s-0028-1093624
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© Georg Thieme Verlag KG Stuttgart · New York

Circulating Levels of Immunoreactive Parathyroid Hormone in Endemic Genu Valgum

B.  Sivakumar , K. A.V.R. Krishnamachari
  • National Institute of Nutrition, Indian Council of Medical Research, Jamai Osmania, Hyderabad, India
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Publication Date:
23 December 2008 (online)

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Abstract

Circulating levels of immunoreactive parathyroid hormone (PTH) were estimated in fifteen normal subjects and twenty-five subjects suffering from skeletal fluorosis, ten of whom had associated endemic genu valgum. Levels of PTH were high in all the subjects with fluorosis as compared to normals, but among fluorosis subjects, those who had endemic genu valgum had values strikingly higher than those without. It is suggested that secondary hyperparathyroidism may have a significant role to play in the pathogenesis of osteoporosis seen in patients with endemic genu valgum.

Key words

Immunoreactive Parathyroid Hormone - Fluorosis - Osteoporosis - Genu Valgum