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Horm Metab Res 1979; 11(12): 648-654
DOI: 10.1055/s-0028-1092792
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© Georg Thieme Verlag KG Stuttgart · New York

Metabolic and Behavioral Differences between Dieting and Intestinal Bypass

G. A. Bray1 , W. T. Dahms1 , R. L. Atkinson1 , J.  Rodin2 , I.  Taylor3 , C.  Frame1 , A.  Schwartz1
  • 1Departments of Medicine, Pediatrics and Surgery, UCLA School of Medicine, Harbor Generale Hospital Campus Torrance, California
  • 2Department of Psychology, Yale University, New Haven, Connecticut
  • 3Center for Ulcer Research and Education, Wadsworth Veterans Administration Hospital, Los Angeles California, U.S.A.
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Publication History

Publication Date:
17 December 2008 (online)

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Abstract

The present studies were designed to compare physiological and behavioral changes produced by weight loss induced with dieting and the weight loss which follows intestinal bypass. A group of 7 grossly obese individuals were hospitalized in a metabolic unit and studied at their initial weight after 4 weeks on a hypocaloric diet and again following a comparable weight loss after intestinal bypass surgery. The score indicating depression increased after dieting, but returned to initial levels after bypass. A number of other behavioral changes were recorded including a reduction in the time spent thinking about food, the time when the individual felt hungry and a greater percentage of time when they felt "full". After bypass, the patients also selected and ate smaller quantities of food. There were no metabolic differences following the period of dieting. Among the metabolic changes after bypass were an increase in glycerol and a decrease in insulin. The possible relationships between the metabolic and behavioral changes have been reviewed.

Key words

Weight Loss - Hypocaloric Diet - Intestinal Bypass - Metabolic and Behavioral Differences

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