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Synfacts 2008(11): 1175-1175
DOI: 10.1055/s-0028-1083452
DOI: 10.1055/s-0028-1083452
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag
Stuttgart ˙ New York
Iridium-Catalyzed Hydrogenation of 7,8-Dihydro-quinolin-5(6H)-ones
X.-B. Wang, W. Zeng, Y.-G. Zhou*
Dalian Institute of Chemical Physics, P. R. of China
Further Information
Publication History
Publication Date:
23 October 2008 (online)
Significance
Asymmetric hydrogenation of pyridine derivatives is a relatively new area. The current work represents one of the few methods to achieve excellent enantiomeric excesses for these reactions. The authors also pointed out some of the more challenging substrates for hydrogenation.