Subscribe to RSS
DOI: 10.1055/a-2343-4100
Zementaustritt nach Augmentation osteoporotischer Wirbelkörper
Article in several languages: deutsch | EnglishZusammenfassung
Einleitung
Der Zementaustritt ist die häufigste Komplikation bei der Zementaugmentation von Wirbelkörpern. In der vorliegenden Studie wurden die Zementaustrittsraten bei Zementaugmentationen an der Wirbelsäule untersucht und potenzielle Risikofaktoren für einen Zementaustritt identifiziert.
Methodik
Es wurden 140 Fälle von 131 Patienten und Patientinnen und 9 Verstorbenen ausgewertet. Insgesamt wurden 258 zementaugmentierte Wirbelkörper untersucht. Die Daten dafür stammen aus den Krankenhausdokumentationen von 131 Patienten und Patientinnen, die sich in 2 orthopädisch-unfallchirurgischen Kliniken in der BRD solchen Operationen unterzogen, sowie aus den Untersuchungen von 9 Sterbefällen im Institut für Rechtsmedizin der Universitätsklinikums Hamburg-Eppendorf.
Ergebnisse
Zementaustritte wurden in 64 der 140 Fälle (45,7%) ermittelt. Lokale Zementaustritte waren mit 73,4% (n = 47) die häufigste Austrittsart. Venöse Austritte wurden in 15 Fällen (23,4%) und Lungenzementembolisationen in 2 Fällen (3,1%) evaluiert. Innerhalb des Kollektivs der retrospektiv untersuchten Fälle (n = 131) erlitt lediglich 1 Patient (0,8%) einen symptomatischen Zementaustritt. Als Risikofaktoren für Zementaustritte konnten Zementaugmentationen von Frakturen an Lendenwirbelkörpern sowie eine hohe applizierte Zementmenge identifiziert werden.
Schlussfolgerung
Sowohl die Daten in der assoziierten Literatur als auch die Ergebnisse dieser Arbeit belegen eine hohe Inzidenz von Zementaustritten nach Wirbelkörperaugmentationen. Trotz des geringen prozentualen Anteils symptomatischer Fälle sollten bei der Planung und Durchführung von Zementaugmentationen an Wirbelkörpern die möglichen Einflussfaktoren für einen Zementaustritt berücksichtigt und in die OP-Planung einbezogen werden.
Publication History
Received: 28 September 2023
Accepted after revision: 07 June 2024
Article published online:
12 August 2024
© 2024. Thieme. All rights reserved.
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany
-
Literatur
- 1 Kanis JA, Norton N, Harvey NC. et al. SCOPE 2021: a new scorecard for osteoporosis in Europe. Arch Osteoporos 2021; 16: 82
- 2 Willers C, Norton N, Harvey NC. et al. Osteoporosis in Europe: a compendium of country-specific reports. SCOPE review panel of the IOF. Arch Osteoporos 2022; 17: 23
- 3 Layton KF, Thielen KR, Koch CA. et al. Vertebroplasty, first 1000 levels of a single center: evaluation of the outcomes and complications. AJNR Am J Neuroradiol 2007; 28: 683-689
- 4 Lee MJ, Dumonski M, Cahill P. et al. Percutaneous treatment of vertebral compression fractures: a meta-analysis of complications. Spine (Phila Pa 1976) 2009; 34: 1228-1232
- 5 Martín-Fernández M, López-Herradón A, Piñera AR. et al. Potential risks of using cement-augmented screws for spinal fusion in patients with low bone quality. Spine J 2017; 17: 1192-1199
- 6 Duffau P, Beylot-Barry M, Palussiere J. et al. Necrotic livedo after vertebroplasty. Br J Dermatol 2007; 156: 382-383
- 7 Lamparello NA, Jaswani V, DeSousa K. et al. Percutaneous retrieval of an embolized kyphoplasty cement fragment from the pulmonary artery: A case report and literature review. J Radiol Case Rep 2016; 10: 40-47
- 8 Chung SE, Lee SH, Kim TH. et al. Renal cement embolism during percutaneous vertebroplasty. Eur Spine J 2006; 15 (Suppl. 5) 590-594
- 9 Dash A, Brinster DR. Open heart surgery for removal of polymethylmethacrylate after percutaneous vertebroplasty. Ann Thorac Surg 2011; 91: 276-278
- 10 Fadili Hassani S, Cormier E, Shotar E. et al. Intracardiac cement embolism during percutaneous vertebroplasty: incidence, risk factors and clinical management. Eur Radiol 2019; 29: 663-673
- 11 Anselmetti GC, Manca A, Hirsch J. et al. Percutaneous vertebroplasty in osteoporotic patients: an institutional experience of 1,634 patients with long-term follow-up. J Vasc Interv Radiol 2011; 22: 1714-1720
- 12 Lee JK, Jeong HW, Joo IH. et al. Percutaneous balloon kyphoplasty for the treatment of very severe osteoporotic vertebral compression fractures: a case-control study. Spine J 2018; 18: 962-969
- 13 Kim JH, Ahn DK, Shin WS. et al. Clinical effects and complications of pedicle screw augmentation with bone cement: comparison of fenestrated screw augmentation and vertebroplasty augmentation. Clin Orthop Surg 2020; 12: 194-199
- 14 Chotivichit A, Korwutthikulrangsri E, Churojana A. et al. Complications in vertebroplasty. J Med Assoc Thai 2012; 95 (Suppl. 9) S75-S81
- 15 Hsieh MK, Kao FC, Chiu PY. et al. Risk factors of neurological deficit and pulmonary cement embolism after percutaneous vertebroplasty. J Orthop Surg Res 2019; 14: 406
- 16 Kim YJ, Lee JW, Park KW. et al. Pulmonary cement embolism after percutaneous vertebroplasty in osteoporotic vertebral compression fractures: incidence, characteristics, and risk factors. Radiology 2009; 251: 250-259
- 17 Ulusoy OL, Kahraman S, Karalok I. et al. Pulmonary cement embolism following cement-augmented fenestrated pedicle screw fixation in adult spinal deformity patients with severe osteoporosis (analysis of 2978 fenestrated screws). Eur Spine J 2018; 27: 2348-2356
- 18 Butscheidt S, Rolvien T, Ritter J. Pulmonary cement embolism is not associated with the cause of death in a post-mortem cohort of cement-augmented interventions in the spine. Eur Spine J 2018; 27: 2593-2601
- 19 Chen W, Xie W, Xiao Z. et al. Incidence of cement leakage between unilateral and bilateral percutaneous vertebral augmentation for osteoporotic vertebral compression fractures: a meta-analysis of randomized controlled trials. World Neurosurg 2019; 122: 342-348
- 20 Guo HZ, Tang YC, Guo DQ. et al. The cement leakage in cement-augmented pedicle screw instrumentation in degenerative lumbosacral diseases: a retrospective analysis of 202 cases and 950 augmented pedicle screws. Eur Spine J 2019; 28: 1661-1669
- 21 Ishak B, Bajwa AA, Schneider T. et al. Early complications and cement leakage in elderly patients who have undergone intraoperative computed tomography (CT)-guided cement augmented pedicle screw placement: eight-year single-center experience. World Neurosurg 2019; 128: e975-e981
- 22 Kim BS, Hum B, Park JC. et al. Retrospective review of procedural parameters and outcomes of percutaneous vertebroplasty in 673 patients. Interv Neuroradiol 2014; 20: 564-575
- 23 Shi X, Cui Y, Pan Y. et al. Prediction of early vascular cement leakage following percutaneous vertebroplasty in spine metastases: the Peking University First Hospital Score (PUFHS). BMC Cancer 2021; 21: 764
- 24 Zhan Y, Jiang J, Liao H. et al. Risk factors for cement leakage after vertebroplasty or kyphoplasty: a meta-analysis of published evidence. World Neurosurg 2017; 101: 633-642
- 25 Gu CN, Brinjikji W, Evans AJ. et al. Outcomes of vertebroplasty compared with kyphoplasty: a systematic review and meta-analysis. J Neurointerv Surg 2016; 8: 636-642
- 26 Jing Z, Dong J, Li Z. et al. Single balloon versus double balloon bipedicular kyphoplasty: a systematic review and meta-analysis. Eur Spine J 2018; 27: 2550-2564
- 27 Wei H, Dong C, Zhu Y. et al. Analysis of two minimally invasive procedures for osteoporotic vertebral compression fractures with intravertebral cleft: a systematic review and meta-analysis. J Orthop Surg Res 2020; 15: 401
- 28 Yin P, Ji Q, Wang Y. et al. Percutaneous kyphoplasty for osteoporotic vertebral compression fractures via unilateral versus bilateral approach: A meta-analysis. J Clin Neurosci 2019; 59: 146-154
- 29 Schmidt R, Cakir B, Mattes T. et al. Cement leakage during vertebroplasty: an underestimated problem?. Eur Spine J 2005; 14: 466-473
- 30 Tomé-Bermejo F, Piñera AR, Duran-Álvarez C. et al. Identification of risk factors for the occurrence of cement leakage during percutaneous vertebroplasty for painful osteoporotic or malignant vertebral fracture. Spine (Phila Pa 1976) 2014; 39: E693-E700
- 31 Abousayed M, Boktor JG, Sultan AM. et al. Augmentation of fenestrated pedicle screws with cement in patients with osteoporotic spine. J Craniovertebr Junction Spine 2018; 9: 20-25
- 32 Coniglio A, Rava A, Fusini F. et al. Effectiveness and reliability of cannulated fenestrated screws augmented with polymethylmethacrylate cement in the surgical treatment of osteoporotic vertebral fractures. J Craniovertebr Junction Spine 2021; 12: 33-37
- 33 Gaik C, Schmitt N, Wiesmann T. [Bone cement implantation syndrome – pathophysiology, diagnostics & treatment options]. Anästh Intensivmed 2019; 60: 124-133
- 34 Hård Af Segerstad M, Olsen F, Erik Houltz E. et al. Inhaled prostacyclin for the prevention of increased pulmonary vascular resistance in cemented hip hemiarthroplasty – A randomised trial. Acta Anaesthesiol Scand 2019; 63: 1152-1161
- 35 Zhan Y, Jiang J, Liao H. et al. Risk factors for cement leakage after vertebroplasty or kyphoplasty: a meta-analysis of published evidence. World Neurosurg 2017; 101: 633-642
- 36 Ding J, Zhang Q, Zhu J. et al. Risk factors for predicting cement leakage following percutaneous vertebroplasty for osteoporotic vertebral compression fractures. Eur Spine 2016; 25: 3411-3417
- 37 Zhu SY, Zhong ZM, Wu Q. et al. Risk factors for bone cement leakage in percutaneous vertebroplasty: a retrospective study of four hundred and eighty five patients. Int Orthop 2016; 40: 1205-1210
- 38 Nieuwenhuijse MJ, Bollen L, van Erkel AR. et al. Optimal intravertebral cement volume in percutaneous vertebroplasty for painful osteoporotic vertebral compression fractures. Spine (Phila Pa 1976) 2012; 37: 1747-1755
- 39 Duan ZK, Zou JF, He XL. et al. Bone-filling mesh container versus percutaneous kyphoplasty in treating Kümmell’s disease. Arch Osteoporos 2019; 14: 109
- 40 Zhang B, Chen G, Yang X. et al. Percutaneous kyphoplasty versus percutaneous vertebroplasty for neurologically intact osteoporotic Kümmell’s disease: a systematic review and meta-analysis. Global Spine J 2022; 12: 308-322
- 41 Limthongkul W, Karaikovic EE, Savage JW. et al. Volumetric analysis of thoracic and lumbar vertebral bodies. Spine J 2010; 10: 153-158
- 42 Griessenauer CJ, Raborn J, Foreman P. et al. Venous drainage of the spine and spinal cord: a comprehensive review of its history, embryology, anatomy, physiology, and pathology. Clin Anat 2015; 28: 75-87
- 43 Tobinick E, Vega CP. The cerebrospinal venous system: anatomy, physiology, and clinical implications. MedGenMed 2006; 8: 53
- 44 Nieuwenhuijse MJ, van Erkel AR, Dijkstra PDS. et al. Cement leakage in percutaneous vertebroplasty for osteoporotic vertebral compression fractures: identification of risk factors. Spine J 2011; 11: 839-848
- 45 Anselmetti GC, Zoarski G, Manca A. et al. Percutaneous vertebroplasty and bone cement leakage: clinical experience with a new high-viscosity bone cement and delivery system for vertebral augmentation in benign and malignant compression fractures. Cardiovasc Intervent Radiol 2008; 31: 937-947