Thieme E-Books & E-Journals - Zeitschrift für Gastroenterologie / Issue

L 1.01

Khanal, Rajendra; Yang, Taihua; Poenisch, Marion; Taubert, Richard; Engel, Bastian; Jaeckel, Elmar; Vogel, Arndt; Cantz, Tobias; Chevessier, Frédéric; Balakrishnan, Asha; Ott, Michael; Sharma, AmarDeep: mRNA therapeutics for liver diseases: HNF4A mRNA delivery via lipid nanoparticles attenuates liver fibrosis in preclinical models.

Abstract
HTML

L 1.02

Gaitantzi, Haristi; Birgin, Emrullah; Rasbach, Erik; Breitkopf-Heinlein, Katja; Rahbari, Nuh: Generation of human liver organoids – An in vitro model of liver diseases

Abstract
HTML

L 1.03

Gross, Simon; Danielyan, Lusine; Klein, Kathrin; Schwab, Matthias; Buechler, Christa; Melter, Michael; Weiss, ThomasS.: Expression of Amyloid Beta42 and its metabolizing proteins is altered in steatosis and non-alcoholic steatohepatitis (NASH)

Abstract
HTML

L 2.01

Klement, LukasJohannes; Jansakun, Chutima; Tuma-Keller, Sabine; Staffer, Simone; Altamura, Sandro; Muckenthaler, Martina; Merle, Uta; Chamulitrat, Walee: Macrophage-specific PLA2g6 deficiency exacerbates liver injury during bacterial sepsis via myelopoiesis activation in male mice

Abstract
HTML

L 2.02

Altenmüller, Johannes; Sebode, Marcial; Weiler-Normann, Christina; Wiegard, Christiane; Lohse, Ansgar; Schramm, Christoph: Ultraschall in der Erkennung und Beurteilung von Gallenblasenpolypen bei PSC: Cut-off von 8,5mm Größe eignet sich zur Prädiktion eines malignen Polypen

Abstract
HTML

L 2.03

Stindt, Jan; Behrendt, Annika; Stalke, Amelie; Dröge, Carola; Pfister, Eva-Doreen; Baumann, Ulrich; Gohlke, Holger; Lüdde, Tom; Keitel-Anselmino, Verena: In vitro and in silico characterization of a novel NR1H4/FXR mutation causing Progressive Familial Intrahepatic Cholestasis Type 5

Abstract
HTML

L 3.01

Ribback, Silvia; Peters, Kristin; Wilhelmi, Paula; Su, Qin; Dombrowski, Frank; Bannasch, Peter: Hepatocellular ballooning in liver cirrhosis is due to glycogenotic metabolic aberrations with facultative steatosis and ground glass formation

Abstract
HTML

L 3.02

Wieloch, Judith; Lemme, Mandy; Henkel, Janin; Püschel, GerhardP.: Direct impact of fructose on hepatic lipid and glycogen metabolism

Abstract
HTML

L 3.03

Deschler, Sebastian; Bauer, Ulrike; Ringelhan, Marc; Geisler, Fabian; Schmid, RolandM.; Knolle, PercyA.; Böttcher, Katrin: Free fatty acids induce impairment of mitochondrial function and cytokine expression in mucosal-associated invariant T (MAIT) cells in NAFLD

Abstract
HTML

L 4.01

Brandt, ElisaFabiana; Wirtz, TheresaHildegard; Li, Zhijian; Ibrahim, Mahmoud; Fischer, Petra; Beckers, Anika; Flaßhove, Alexander; Peters, Linsey; Costa, Ivan; Kramann, Rafael; van der Vorst, EmielP.C.; Liedtke, Christian; Sahin, Hacer; Trautwein, Christian; Berres, Marie-Luise: CXCR3 is a key regulator during macrophage differentiation and has a significant impact on tumor-associated macrophages

Abstract
HTML

L 4.02

Gerber, TiemoS.; Goeppert, Benjamin; Witzel, Hagen; Hausen, Anne; Fabian, Bartsch; Schindeldecker, Mario; Heuft, Lisa-Katharina; Ridder, Dirk; Gaida, MatthiasM.; Schirmacher, Peter; Lang, Hauke; Straub, BeateK.: N-cadherin distinguishes intrahepatic cholangiocarcinoma from ductal adenocarcinoma of the pancreas

Abstract
HTML

L 4.03

Julia, Piche; Antje, Mohs; Marius, MaximilianWoitok; Christian, Trautwein; Tobias, Otto: ACSL4-dependent ferroptosis is not a major tumor-suppressive mechanism during HCC initiation and progression

Abstract
HTML

L 5.01

Heim, Kathrin; Sagar, Sagar; Hofmann, Maike; Thimme, Robert: Enforced cytotoxic signature of HBV pol455-specific CD8 T cells in chronic HBV infection

Abstract
HTML

L 5.02

Langer, Mona-May; Sichelschmidt, Stefanie; Bauschen, Alina; Guckenbiehl, Sabrina; Bornemann, Lea; Gunzer, Matthias; Lange, Christian: Impaired neutrophil migration is association with adverse outcomes in patients with liver cirrhosis

Abstract
HTML

L 5.03

Wulf, Severin; Niehaus, Christian; Behrendt, Patrick; Maasoumy, Benjamin; Wedemeyer, Heiner; Krey, Thomas; Cornberg, Markus; Kraft, AnkeR.M.: Comprehensive characterization of Mucosal-Associated invariant T (MAIT) cells in patients with hepatitis E virus infection

Abstract
HTML

P 1.01

Voigt, Christoph; Buchner, Monika; Melter, Michael; Dayoub, Rania; Weiss, ThomasS.: Augmenter of Liver Regeneration (ALR) alters IL-6 signaling in liver cells by affecting IL-6 receptor subunits gp80 and gp130

Abstract
HTML

P 1.02

Straßmann, Jan; von Bülow, Verena; Wrobel, Sarah; Grevelding, Christoph; Quack, Thomas; Köhler, Kernt; Roderfeld, Martin; Roeb, Elke: Is the effectivity of Schistosoma mansoni infection dependent on the host’s age?

Abstract
HTML

P 1.03

Wu, Hanghang; Chen, Chaobo; Ye, Hui; Tortajada, Agustín; Rodríguez-Perales, Sandra; Torres-Ruiz, Raúl; Villanueva, Alberto; Vidal, August; Peligros, MariaIsabel; Reissing, Johanna; Bruns, Tony; Mohamed, MohamedRamadan; Zheng, Kang; Vaquero, Javier; Bañares, Rafael; Nelson, LeonardJ.; Trautwein, Christian; Davis, RogerJ.; Martinez-Naves, Eduardo; Nevzorova, YuliaA.; Avila, MatiasA.; Cubero, FranciscoJavier: Activation of the unfolded protein response (UPR) and fibrosis is associated withcholangiocellular injury in an experimental model of fibropolycystic liver disease

Abstract
HTML

P 1.04

Fischer, Natalie; Haderer, Marika; Neubert, Philip; Gschwendtner, Heidi; Kunst, Claudia: Aktive Rolle von Bakterien bei der spontan bakteriellen Peritonitis: Regulation der p53 Familie in Darmepithelzellen

Abstract
HTML

P 1.05

Kolligs, Frederik; Backu, Elisabeth; Gschwind, Dana; Gülow, Karsten; Kunst, Claudia; Müller-Schilling, Martina: IGFBP2 – ein neues Zielgen der p53-Familie mit anti-proliferativen Effekten in Hepatomzellen

Abstract
HTML

P 1.06

Brödel, Susan; Krawczyk, Marcin; Lammert, Frank; Weber, SusanneN.: C5aR deficiency rescues hepatic fibrosis but hampers fibrotic resolution

Abstract
HTML

P 1.07

Eisner, Ulrike; Sommer, Judith; Thasler, Wolfgang; Bosserhoff, Anja; Hellerbrand, Claus: Enhanced expression of bone morphogenetic protein endothelial cell-precursor derived regulator in liver fibrosis

Abstract
HTML

P 1.08

Rinner, Eva; Haderer, Marika; Kunst, Claudia; Gülow, Karsten; Müller-Schilling, Martina: Bacterial induced deradation of cell-to-cell contact proteins and loss of epithelial integrity in spontaneous bacterial peritonitis

Abstract
HTML

P 1.09

Seitz, Tatjana; Kremer, AndreasE.; Freese, Kim; Hellerbrand, Claus: Role of Fibroblast Growth Factor 9 in bile acid homeostasis

Abstract
HTML

P 1.10

Bewersdorf, Lisa; Luo, Yizhao; Schmitz, Annika; Cramer, Thorsten; Strnad, Pavel: The role of the mechanistic target of rapamycin (mTOR) in Alpha-1 Antitrypsin Deficiency

Abstract
HTML

P 1.11

Seitz, Tatjana; Freese, Kim; Thasler, WolfgangErwin; Hellerbrand, Claus: Enhanced Expression of Fibroblast Growth Factor 9 in Hepatic Fibrosis

Abstract
HTML

P 1.12

Nimphy, Jonas; Ibrahim, Sara; Melter, Michael; Dayoub, Rania; Weiss, ThomasS.: Expression of liver regeneration-associated protein ALR (Augmenter of Liver Regneration) is diminished by IL-1β

Abstract
HTML

P 1.13

Kasi, Amoon; Goreth, Alicia; Schlitt, HansJürgen; Geissler, Edward; Eggenhofer, Elke: Effects of regulated cell death (e. g. ferroptosis) on early hepatic ischemia reperfusion damage in steatotic donor organs

Abstract
HTML

P 1.14

Kraus, Nico; Moeslein, Magnus; Schierwagen, Robert; Ortiz, Cristina; Torres, Sandra; Tyc, Olaf; Hieber, Christoph; Meier, Caroline; Müller, Elena; Holz, Frederik; Gu, Wenyi; Brol, Maximilian; Zeuzem, Stefan; Trebicka, Jonel; Klein, Sabine; Uschner, FrankErhard: New Rat Model of Cholestatic Liver Cirrhosis Developing Acute-on-Chronic-Liver failure

Abstract
HTML

P 1.15

Kraus, Nico; Uschner, FrankErhard; Moeslein, Magnus; Schierwagen, Robert; Ortiz, Cristina; Torres, Sandra; Tyc, Olaf; Hieber, Christoph; Meier, Caroline; Gu, Wenyi; Müller, Elena; Brol, Maximilian; Zeuzem, Stefan; Trebicka, Jonel; Klein, Sabine: New Rat Model of Alcoholic Liver Cirrhosis Developing Acute-on-Chronic-Liver failure

Abstract
HTML

P 1.16

Kraus, Nico; Moeslein, Magnus; Schierwagen, Robert; Ortiz, Cristina; Torres, Sandra; Tyc, Olaf; Hieber, Christoph; Meier, Caroline; Müller, Elena; Holz, Frederik; Gu, Wenyi; Brol, Maximilian; Zeuzem, Stefan; Uschner, FrankErhard; Trebicka, Jonel; Klein, Sabine: New Rat Model of Advanced Non-Alcoholic-Steatohepatitis-Cirrhosis Developing Acute-on-Chronic-Liver failure

Abstract
HTML

P 1.17

Erdem, Merve; Cramer, Thorsten: Dietary carbohydrate restriction inhibits carbon tetrachloride-induced murine liver fibrosis

Abstract
HTML

P 1.18

Bogovic, Niklas; Schlitt, HansJ.; Werner, JensM.; Junger, Henrik: Profibrotic cytokines in nonalcoholic steatohepatitis (NASH) liver biopsies visualized and quantified by chromogenic in situ hybridization

Abstract
HTML

P 1.19

Feng, Rilu; Sticht, Carsten; Kan, Kejia; Munker, Stefan; Ebert, MatthiasP.; Dooley, Steven; Weng, Hong-Lei: Insulin-controlled C/EBPα expression determines the impact of TGF-β on HNF4α transcription in hepatocytes

Abstract
HTML

P 1.20

Li, Yujia; Pioronska, Weronika; Nwosu, Zeribe; Fan, Weiguo; Ebert, MatthiasP.A.; Dooley, Steven; Wang, Sai: Downregulation of ECM1 in hepatocytes as a damage response to liver injury

Abstract
HTML

P 1.21

Erdoesi, Pia; Buettner, Maren; Meyer-Bender, Matthias; Kamies, Rizqah; Deligiannis, IoannisK.; Menden, MichaelP.; Dooley, Steven; Martinez-Jimenez, CeliaP.; Ogris, Christoph; Hammad, Seddik: Multi-omics profiling identifies molecular signatures of acute-on-chronic liver failure in Abcb4KO mice upon chemical intoxication

Abstract
HTML

P 1.22

Schreiter, Thomas; Gieseler, RobertK.; Vílchez-Vargas, Ramiro; Jauregui, Ruy; Sowa, Jan-Peter; Klein-Scory, Susanne; Broering, Ruth; Croner, RolandS.; Treckmann, JürgenW.; Link, Alexander; Canbay, Ali: Age-related analysis of transcriptome-wide sequencing of human liver

Abstract
HTML

P 1.23

Mueller, Johannes; Wang, Shijin; Chen, Cheng; Elshaarawy, Omar; Rausch, Vanessa; Mueller, Sebastian: The role of PNPLA3, MBOAT7 and TM6SF2 during alcohol detoxification: different mechanisms of fibrosis and steatosis development

Abstract
HTML

P 1.24

Vollmuth, Selina; Schweigert, Alina; Reichert, Doreen; Luedde, Tom; Kordes, Claus: Mechanically stimulated hepatic stellate cells release WNT5A that triggers apoptosis in HCC cell lines

Abstract
HTML

P 1.25

Wolf, StephanieD.; Ehlting, Christian; Stühler, Kai; Poschmann, Gereon; Petzsch, Patrick; Lautwein, Tobias; Köhrer, Karl; Helm, Barbara; Klingmüller, Ursula; Luedde, Tom; Bode, JohannesG.: Interference of TGFb with the activation state of liver macrophages and consequences for liver injury and regeneration

Abstract
HTML

P 1.26

Stalke, Amelie; Sgodda, Malte; Cantz, Tobias; Skawran, Britta; Lainka, Elka; Hartleben, Björn; Baumann, Ulrich; Pfister, Eva-Doreen: KIF12 variants and disturbed hepatocyte polarity in children with a phenotypic spectrum of cholestatic liver disease

Abstract
HTML

P 2.01

Gairing, SimonJohannes; Anders, Julian; Kaps, Leonard; Nagel, Michael; Michel, Maurice; Kremer, WolfgangMaximilian; Hilscher, Max; Galle, PeterRobert; Schattenberg, JörnM.; Wörns, Marcus-Alexander; Labenz, Christian: Evaluation of Interleukin-6 for stepwise diagnosis of minimal hepatic encephalopathy in patients with liver cirrhosis

Abstract
HTML

P 2.02

Thomann, Stefan; Sprengel, SimonDavid; Liermann, Jakob; Tóth, Marcell; Sticht, Carsten; Schirmacher, Peter: Subclassification of human hepatic hemangiomas reveals cellular and functional heterogeneity

Abstract
HTML

P 2.03

Patrick, Huber; Asala, Nassar; Daniela, Stallmann; Diana, Sharipova; Muataz, AliHamad; Marlene, Reincke; Lukas, Sturm; Michael, Schultheiß; Daniel, Duerschmied; Robert, Thimme; Krystin, Krauel; Dominik, Bettinger: Platelet function testing in patients with liver cirrhosis and TIPS implantation

Abstract
HTML

P 2.04

Kaps, Leonard; Hildebrand, Katharina; Nagel, Michael; Michel, Maurice; Kremer, WolfgangMaximilian; Hilscher, Max; Galle, Peter; Schattenberg, Jörn; Wörns, MarcusAlexander; Labenz, Christian: Anwendbarkeit des EncephalApp Stroop Tests als Screening Tool für minimale hepatische Enzephalopathie bei Patienten mit Leberzirrhose in Deutschland

Abstract
HTML

P 2.05

Kremer, WolfgangMaximilian; Vasiliki, Esmeralda; Ismail, Esmeralda; Hilscher, Max; Kaps, Leonard; Michel, Maurice; Schattenberg, JörnM.; Galle, PeterRobert; Sprinzl, Martin; Wörns, MarcusAlexander; Nagel, Michael; Labenz, Christian: Insights into the clinical course and patterns of bacterial infections in patients with liver cirrhosis

Abstract
HTML

P 2.06

Graf, Christiana; Arncken, Jeannette; Lange, ChristianM.; Willuweit, Katharina; Schattenberg, JörnM.; Seessle, Jessica; Lang-Meli, Julia; Böttler, Tobias; Dietz, Julia; Wetzstein, Nils; Mondorf, Antonia; Vermehren, Johannes; Rohde, Gernot; Zeuzem, Stefan; Pathil, Anita: Hepatic Sarcoidosis: Clinical Characteristics and Outcome

Abstract
HTML

P 2.07

Reincke, Marlene; Goetz, Christian; Sturm, Lukas; Huber, Patrick; Thimme, Robert; Schultheiß, Michael; Bettinger, Dominik: Hepatic decompensation after transarterial radioembolization (TARE) – a retrospective analysis of risk factors and outcome of patients with HCC

Abstract
HTML

P 2.08

Tauschek, LauraM.; Brennfleck, FrankW.; Schlitt, HansJ.; Brunner, StefanM.; Junger, Henrik: Novel in situ hybridization and multiplex immunofluorescence technology combined with whole-slide digital image analysis in liver tissue

Abstract
HTML

P 2.09

Junger, Henrik; Luerken, Lukas; Kees, Martin; Prasser, Christopher; Scharf, Gregor; Schlitt, Alexandra; Brennfleck, FrankW.; Dienemann, Thomas; Graf, BernhardM.; Stroszczynski, Christian; Schlitt, HansJ.; Brunner, StefanM.: Successful surgical-multimodal treatment for vaccine-induced complete splanchnic vein thrombosis after ChAdOx1 nCoV-19 vaccination

Abstract
HTML

P 2.10

Michel, Maurice; Hess, Cornelius; Kaps, Leonard; Kremer, WolfgangM.; Hilscher, Max; Galle, PeterR.; Moehler, Markus; Schattenberg, JörnM.; Wörns, Marcus-Alexander; Labenz, Christian; Nagel, Michael: Elevated serum levels of methylglyoxal are associated with impaired liver function in patients with liver cirrhosis

Abstract
HTML

P 2.11

Pavel, Vlad; Gößmann, Holger; Mester, Patricia; Gülow, Karsten; Kunst, Claudia; Müller-Schilling, Martina: Partial splenic embolization used for rescue treatment for variceal bleeding - monocentric experience over four years

Abstract
HTML

P 2.12

Tews, Hauke; Engelke, Carsten; Maaß, Carlos; Kraus, Martin; Dobbermann, Henrike; Marquardt, Jens; Kirstein, Martha: Klinischer Verlauf und Therapieadhärenz nach Ösophagusvarizenligaturen

Abstract
HTML

P 2.13

Langer, Mona-May; Bauschen, Alina; Guckenbiehl, Sabrina; Hoenes, Sebastian; Zwanziger, Denise; Moeller, Lars; Lange, ChristianM.: Thyroid hormone alterations are associated with decompensated liver cirrhosis and acute-on-chronic liver failure

Abstract
HTML

P 2.14

Tergast, TammoLambert; Schultalbers, Marie; Stockhoff, Lena; Simon, Nicolas; Wedemeyer, Heiner; Jaeckel, Elmar; Cornberg, Markus; Maasoumy, Benjamin: Getunnelte Peritonealkatheter als alternative Behandlungssmöglichkeit von therapierefraktärem Aszites bei Patienten mit Leberzirrhose

Abstract
HTML

P 2.15

Schregel, Ida; Eaton, John; Jones, Randall; Ramos, GuilhermePiovezani; Levy, Cynthia; Ioannou, Stephanie; Culver, Emma; Färkkilä, Martti; Chazouilleres, Olivier; Müller, Tobias; Nayagam, Jeremy; Joshi, Deepak; Zigmond, Ehud; Shibolet, Oren; Drenth, Joost; Hoentjen, Frank; Geerts, Anja; Weismüller, Tobias; Zhou, Taotao; Schramm, Christoph: Safety and efficacy of the JAK-inhibitor tofacitinib in patients with primary sclerosing cholangitis: a multicentre, retrospective study

Abstract
HTML

P 2.16

Ruether, Darius; Schaub, Golda; Düngelhoef, Paul; Haag, Friedrich; Wehmeyer, Malte; Fischer, Lutz; Addo, Marylyn; Lütgehetmann, Marc; Lohse, Ansgar; zur Wiesch, JulianSchulze; Sterneck, Martina: Risk factors for a suboptimal immune response to SARS-CoV-2 vaccination in liver transplant recipients

Abstract
HTML

P 2.17

Müller, SophieElisabeth; Ripoll, Cristina; Zipprich, Alexander; Bruns, Tony; Horn, Paul; Krawczyk, Marcin; Lammert, Frank; Reichert, MatthiasChristian: Machine learning models predicting decompensation in cirrhosis

Abstract
HTML

P 2.18

Wiest, Isabella; Serra, Carla; Demolo, Chiara; Zhang, Bo; Chen, Yunhao; Cui, Xin-Wu; Teufel, Andreas; Ebert, Matthias; Dietrich, ChristophF.: Sonographic Criteria of Budd-Chiari Syndrome

Abstract
HTML

P 2.19

Reissing, Johanna; Lutz, Philipp; Frissen, Mick; Ibidapo-Obe, Oluwatomi; Reuken, PhilippA.; Wirtz, TheresaH.; Stengel, Sven; Quickert, Stefanie; Rooney, Michael; Große, Karsten; Zimmermann, HenningWolfgang; Trautwein, Christian; Stallmach, Andreas; Bruns, Tony: The immunomodulatory receptor VSIG4 is released during spontaneous bacterial peritonitis and predicts short-term mortality

Abstract
HTML

P 2.20

Remih, Katharina; Durkalski-Mauldin, Valerie; Lee, WilliamM.; Su, Zemin; Krieg, Laura; Karkossa, Isabel; Schubert, Kristin; von Bergen, Martin; Fontana, RobertJohn; Strnad, Pavel: Serum proteomic characterisation in acute liver failure

Abstract
HTML

P 2.21

Janik, Maciej; Smyk, Wiktor; Kruk, Beata; Szczepankiewicz, Benedykt; Górnicka, Barbara; Lebiedzińska-Arciszewska, Magdalena; Potes, Yaiza; Simões, InêsC.M.; Weber, SusanneN.; Lammert, Frank; Więckowski, MariuszR; Milkiewicz, Piotr; Krawczyk, Marcin: MARC1 polymorphism is associated with decreased markers of liver injury and enhanced antioxidant capacity in patients with AIH

Abstract
HTML

P 2.22

Kremer, WolfgangMaximilian; Schwarz, Alexander; Kopf, Stephanie; Michel, Maurice; Labenz, Christian; Galle, PeterRobert; Sivanathan, Visvakanth; Sprinzl, MartinFrnaz: Comparative analysis of muscle quantification by sonography and computed tomography

Abstract
HTML

P 2.23

Dehlke, Karolin; Krause, Linda; Tyufekchieva, Silvana; Murtha-Lemekhova, Anastasia; Mayer, Philipp; Vlasov, Artyom; Buechler, Markus; Klingmueller, Ursula; Mueller, Nikola: Predicting liver regeneration after major resection

Abstract
HTML

P 2.24

Heumann, Philipp; Kandulski, Arne; Schlosser, Sophie; Müller-Schilling, Martina: Phosphatschwankungen bei einem Patienten mit metastasiertem Hepatitis-B-Virus-assoziierten Cholangiozellulären Karzinom (CCC) mit FGFR2-Fusion unter Therapie mit Tenofovir und Pemigatinib

Abstract
HTML

P 2.25

Muth, Vanessa; Gassner, JosephM.G.V.; Michelotto, Julian; Strobl, Felix; Knaub, Kristina; Zimmer, Maximilian; Mossburner, Simon; Pratschke, Johann; Sauer, IgorM.; Raschzok, Nathanael: Bile as parameter for quality assessment during normothermic ex vivo rat liver machine perfusion

Abstract
HTML

P 2.26

Dezfouli, SepehrAbbasi; El Rafidi, Ahmad; Ramouz, Ali; Al-Saeedi, Mohammad; Khajeh, Elias; Mieth, Markus; Stojkovic, Marija; Weber, TimFrederik; Hoffmann, Kathrin; Büchler, MarkusW.; Mehrabi, Arianeb: Intraoperative Drains and Surgical Management of Biliary Complications After Endocystectomy for Hepatic Cystic Echinococcosis are Beneficial

Abstract
HTML

P 2.27

Strobl, Felix; Michelotto, Julian; Muth, Vanessa; Knaub, Kristina; Zimmer, Maximilian; Moosburner, Simon; Pratschke, Johann; Sauer, IgorM.; Raschzok, Nathanael; Gaßner, JosephM.G.V.: Optimising a rodent model of normothermic ex-vivo liver machine perfusion to mimic clinical application

Abstract
HTML

P 2.28

Dezfouli, SepehrAbbasi; Mehrabi, Arianeb; Schlosser, Fabian; Ramouz, Ali; Khajeh, Elias; Ali-Hasan-Al-Saegh, Sadeq; Loos, Martin; Strobel, Oliver; Müller-Stich, Beat; Ünal, UmutKaan; Mieth, Markus; Klauss, Miriam; Chang, De-Hua; Wielpütz, MarkO.; Büchler, MarkusW.; Hackert, Thilo: Validation of the ISGLS classification of bile leakage after pancreatic surgery: A rare but severe complication

Abstract
HTML

P 2.29

Wang, Sai; Feng, Rilu; Wang, Shanshan; Liu, Hui; Shao, Chen; Li, Yujia; Frederik, Link; Munker, Stefan; Liebe, Roman; Meyer, Christoph; Burgermeister, Elke; Ebert, Matthias; Dooley, Steven; Ding, Huiguo; Weng, Honglei: FOXA2 inhibits hyperbilirubinemia through maintaining apical MRP2 expression in acute liver failure

Abstract
HTML

P 2.30

Götz, Markus; Jurczyk, Maria; Grothues, Dirk; Knoppke, Birgit; Junger, Henrik; Melter, Michael; Schlitt, HansJürgen; Brunner, Stefan; Brennfleck, Frank: Biological abdominal wall expansion in pediatric liver recipients after transplantation with large-for-size organs.

Abstract
HTML

P 2.31

Brunner, StefanM.; Knoppke, Birgit; Zuber-Jerger, Ina; Hackl, Christina; Dobsch, Philipp; Weigand, Kilian; Melter, Michael; Schlitt, Hans-Jürgen; Müller-Schilling, Martina; Kandulski, Arne: Intraoperative Cholangioskopie mit dem SpyGlass DS II und SpyGlass Dicover: Technische Machbarkeit und Bedeutung für das chirurgische und klinische Management bei komplexen hepatobiliären Eingriffen

Abstract
HTML

P 2.32

Kreimeyer, Henriette; Sowa, Jan-Peter; Canbay, Ali: Limax as a prognostic marker for survival in acute liver failure

Abstract
HTML

P 2.33

Franz, Anika; Reuken, Philipp; Ripoll, Cristina; Aschenbach, Rene; Teichgraeber, Ulf; Stallmach, Andreas; Zipprich, Alexander: Lack of porto-caval gradient (PCG) increase after transjugular intrahepatic portosystemic shunt (TIPS) implantation under deep sedation is associated to poor survival

Abstract
HTML

P 2.34

Fründt, Thorben; Müller-Rahmel, Luisa; Hübener, Peter; Huber, Samuel; Lohse, Ansgar; Schrader, Jörg: Impact of coagulation parameters and spleen size on bleeding complications in patients with primary liver diseases undergoing mini-laparoscopic liver puncture.

Abstract
HTML

P 2.35

Mueller, Johannes; Wang, Shijin; Chen, Cheng; Elshaarawy, Omar; Mueller, Sebastian: Survival in a 10 year prospective cohort of heavy drinkers: Liver stiffness is the best long-term prognostic parameter

Abstract
HTML

P 2.36

Düngelhoef, Paul-Maria; Hartl, Johannes; Rüther, DariusFerenc; Steinmann, Silja; Kaur, Manmeet; Glaser, FabianVincent; Sterneck, Martina; Sebode, Marcial; Weiler-Normann, Christina; Lütgehetmann, Marc; Schramm, Christoph; zur Wiesch, JulianSchulze; Lohse, Ansgar: Low antibody titers after second SARS-CoV-2 vaccination in patients with autoimmune hepatitis

Abstract
HTML

P 3.01

Tapking, Christian; Kilian, Katja; Hundeshagen, Gabriel; Haug, Valentin; Teufel, Andreas; Houschyar, Khosrow; Kneser, Ulrich; Hirche, Christoph: Hepatic functional pathophysiology and morphological damage following severe burns: a systematic review and meta-analysis

Abstract
HTML

P 3.02

Wirth, Victoria; von Bülow, Verena; Hehr, Laura; Russ, Lena; Baier, Anne; Schramm, Gabriele; Quack, Thomas; Grevelding, ChristophG.; Roderfeld, Martin; Roeb, Elke: Insulin-like growth factor 1 receptor and insulin receptor mediate AP-1-activation in enterocytes stimulated with parasite antigens

Abstract
HTML

P 3.03

Li, Huili; Staffer, Simone; Tuma-Kellner, Sabine; Merle, Uta; Chamulitrat, Walee: Mechanisms of increased triglyceride synthesis and lipolysis induced by Fatty acid Transport Protein 4 deficiency in hepatocytes

Abstract
HTML

P 3.04

Ott, Fritzi; Hochmuth, Luise; Körner, Christiane; Volke, Daniela; Cokan, KajaBlagotinšek; Juvan, Peter; Brosch, Mario; Hofmann, Ute; Hoffmann, Ralf; Rozman, Damjana; Berg, Thomas; Matz-Soja, Madlen: Metabolic dynamics of sexual dimorphism in primary mouse hepatocytes in vitro

Abstract
HTML

P 3.05

Tessenyi, Maximilian; Weber, SusanneN; Reichert, Matthias; Karatayli, SenemC.; Hall, RabeaA; Bruns, Tony; Qiao, Sen; Boehm, Ulrich; Dooley, Steven; Lammert, Frank; Karatayli, Ersin: Circulating miR-148a is a precipitant independent biomarker of acute-on-chronic liver failure (ACLF)

Abstract
HTML

P 3.06

Sydor, Svenja; Engin, Ender; Manka, Paul; Özcürümez, Mustafa; Figge, Anja; Pospiech, Josef; Jähnert, Andreas; Canbay, Ali; Bechmann, Lars: Effects of a one-month religious fast on metabolism and steatotic liver injury in type 2 diabetes

Abstract
HTML

P 3.07

Manka, Paul; Schänzer, Julia; Best, Jan; Vilchez-Vargas, Ramiro; Link, Alexander; Figge, Anja; Jähnert, Andreas; Cubero, Javier; Kahraman, Alisan; Kim, Moon-Sung; Kälsch, Julia; Kinner, Sonja; Faber, KlaasNico; Moshage, Han; Gerken, Guido; Canbay, Ali; Bechmann, Lars; Sydor, Svenja: A potential role for bile acid signalling in celiac disease-associated fatty liver

Abstract
HTML

P 3.08

Ubieto, RaquelBenedé; Estévez-Vázquez, Olga; Dumartin, Marine; Reissing, Johanna; Bruns, Tony; Vaquero, Javier; Liedtke, Christian; Trautwein, Christian; Bañares, Rafael; Cubero, FranciscoJavier; Nevzorova, YuliaA.: Gender-related differences in response to DUAL diet in murine model of steatohepatitis

Abstract
HTML

P 3.09

Cadenas, Cristina; Gianmoena, Kathrin; Gasparoni, Nina; Jashari, Adelina; Gabrys, Philipp; Ghallab, Ahmed; Grgas, Katharina; Walter, Jörn; Hengstler, Jan: Epigenomic and transcriptional profiling identifies impaired glyoxylate detoxification in NAFLD as a risk factor for hyperoxaluria

Abstract
HTML

P 3.10

Gehrke, Nadine; Hofmann, Lea; Galle, PeterR.; Schattenberg, JörnM.: Exploring the role of IL-1, IL-33, and IL-36 signaling in hepatocytes and metabolic liver disease

Abstract
HTML

P 3.11

Sommer, Judith; Hellerbrand, Claus: Four-and-a-half LIM-domain protein (FHL2) affects diet induced obesity, diabetes and hepatic steatosis and inflammation

Abstract
HTML

P 3.12

Kalinowski, Piotr; Smyk, Wiktor; Nowosad, Małgorzata; Paluszkiewicz, Rafał; Michałowski, Łukasz; Ziarkiewicz-Wróblewska, Bogna; Weber, SusanneN.; Lammert, Frank; Zieniewicz, Krzysztof; Krawczyk, Marcin: Common MARC1 and HSD17B13 polymorphism have protective effects on liver injury in obese patients undergoing bariatric surgery

Abstract
HTML

P 3.13

Kasper, Philipp; Martin, Anna; Schwabedissen, AlbrechtMeyerzu; Scherdel, Julia; Lang, Sonja; Goeser, Tobias; Demir, Muenevver; Steffen, Hans-Michael: Uncontrolled hypertension: a neglected risk in patients with NAFLD

Abstract
HTML

P 3.14

Murtha-Lemekhova, Anastasia; Fuchs, Juri; Feiler, Svenja; Schulz, Erik; Teroerde, Miriam; Kalkum, Eva; Klotz, Rosa; Billeter, Adrian; Probst, Pascal; Hoffmann, Katrin: Metabolic syndrome and hepatectomy - a meta-analysis with subgroup analysis for NAFLD

Abstract
HTML

P 3.15

Henkel-Oberländer, Janin; Buchheim-Dieckow, Katja; Castro, JosèP.; Laeger, Thomas; Jöhrens, Korinna; Püschel, GerhardP.: Role of endurance training in diet-induced steatohepatitis in rats

Abstract
HTML

P 3.16

Rau, Monika; Schmitt, Theresa; Krawczyk, Marcin; Lütjohann, Dieter; Monte, MariaJ.; Marin, JoseJ.G.; Geier, Andreas: Elevated serum bile acids in NASH patients with fibrosis in the context of their cholestatic genetic predisposition

Abstract
HTML

P 3.17

Fleissner, Janik; Garbisch, Janine; Lederer, Philipp; Butt, Elke; Zernecke-Madsen, Alma; Geier, Andreas; Hermanns, Heike: Loss of Oncostatin M receptor aggravates dyslipidemia, hepatic lipid accumulation and adipose tissue inflammation in Apoe-deficient mice fed a Western diet

Abstract
HTML

P 3.18

Chen, Cheng; Wang, Shijin; Mueller, Johannes; Mueller, Sebastian: H2O2-mediated autophagy during ethanol metabolism

Abstract
HTML

P 3.19

Wang, Shijin; Chen, Cheng; Mueller, Johannes; Mueller, Sebastian: Liver iron overload in alcoholic liver disease: Crosstalk between endothelial cells and hepatocytes in iron regulation

Abstract
HTML

P 3.20

Wang, Shijin; Chen, Cheng; Mueller, Johannes; Mueller, Sebastian: Evidence for alcohol-mediated masked hemolysis in ALD patients and a vicious cycle of hemolysis and iron-mediated liver damage

Abstract
HTML

P 3.21

Chen, Cheng; Wang, Shijin; Mueller, Johannes; Mueller, Sebastian: In vitro erythrophagocytosis model to study alcohol-mediated heme turnover

Abstract
HTML

P 3.22

Wolf, StephanieD.; Malms, Moritz; Simon, Mascha; Beckmann, Andre; Hustedt, Tobias; Ehlting, Christian; Luedde, Tom; Bode, JohannesG.: Deletion of the thrombin receptor PAR4 reduces diet-induced liver damage

Abstract
HTML

P 3.23

Itzel, Timo; Falconer, Thomas; Daza, Jimmy; Park, Jimyung; Wiest, Isabella; Ebert, Matthias; Hripcsak, George; Teufel, Andreas: Vaccination against upper respiratory infections is a matter of survival in Alcoholic Liver Disease

Abstract
HTML

P 3.24

Schöler, David; Köhler, JanPhilipp; May, Petra; Luedde, Tom; vom Dahl, Stephan: Adult cholesteryl ester storage disease (CESD): Three case reports

Abstract
HTML

P 3.25

Schöler, David; Köhler, JanPhilipp; May, Petra; Thimm, Eva; Mayatepek, Ertan; Luedde, Tom; vom Dahl, Stephan: Niemann-Pick type B as ultra-rare differential diagnosis in hepatomegaly, steatohepatitis, low HDL and increased plasma chitotriosidase activity: three case reports

Abstract
HTML

P 3.26

Wang, Surui; Cendrowski, Jaroslaw; Rekar, Revathi; Motzler, Karsten; Kwon, Yun; Seitz, Susanne; Roden, Michael; Maida, Adriano; Herzig, Stephan; Miaczynska, Marta; Zeigerer, Anja: Liver-specific depletion of an endosomal regulator causes apoptosis, cell death and liver failure

Abstract
HTML

P 3.27

Nalbach, Karsten; Sekar, Revathi; Alfaro, AnaJimena; de Angelis, MartinHrabe; Herzig, Stephan; Roden, Michael; Behrends, Christian; Krahmer, Natalie; Zeigerer, Anja; Motzler, Karsten: Novel function for endosomal trafficking adaptors in hepatic metabolic disease

Abstract
HTML

P 4.01

Peschl, Vanessa; Seitz, Tatjana; Bosserhoff, Anja; Hellerbrand, Claus: Bone morphogenetic protein 13 is expressed by activated hepatic stellate cells and promotes tumorigenicity of hepatocellular carcinoma

Abstract
HTML

P 4.02

Wilhelm, Fabian; Klieser, Eckhard; Neumayer, Bettina; Winkelmann, Paul; Jäger, Tarkan; Pachmayr, Johanna; Ardelt, Maximilian; Huber-Cantonati, Petra; Ablinger, Celina; Pancis, Irina; Ritter, Markus; Kiesslich, Tobias; Mayr, Christian; Neureiter, Daniel: Cdk5 as a possible new target in biliary tract cancer: preliminary in-situ findings

Abstract
HTML

P 4.03

Innes, Hamish; Nischalke, HansDieter; Weiss, KarlHeinz; Gotthardt, Daniel; Guha, Neil; Barnes, Eleanor; Irving, Will; Fischer, Janett; Rosendahl, Jonas; Casper, Markus; Lammert, Frank; Lutz, PhilipL; Mueller, Sebastian; Semmler, Georg; Eyer, Florian; von Felden, Johann; Link, Alexander; Vogel, Arndt; Marquardt, JensU; Sulk, Stefan; Datz, Christian; Reiberger, Thomas; Schafmayer, Clemens; Berg, Thomas; Hampe, Jochen; Stickel, Felix; Buch, Stephan: Variants APOE (rs429358) and TM6SF2 (rs187429064) modify the risk of hepatocellular carcinoma

Abstract
HTML

P 4.04

Cosma, Lidia-Sabina; Weigand, Kilian; Müller-Schilling, Martina; Kandulski, Arne: Lenvatinib as First-line Treatment of Hepatocellular Carcinoma in Patients with Impaired Liver Function in Advanced Liver Cirrhosis: Real World Data and Experience of a Tertiary Hepatobiliary Center

Abstract
HTML

P 4.05

Michalski, Marlen; Schroeder, Anne; Gunkel, Manuela; Müller-Schilling, Martina; Gülow, Karsten: Dimethyl fumarate (DMF) inhibits proliferation and migration and induce cell death in solid tumor cells

Abstract
HTML

P 4.06

Tümen, Deniz; Teubner, Jan-Peter; Aschenbrenner, Elisabeth; Gülow, Karsten; Müller-Schilling, Martina: Introduction of an novel exon-specific isoform expression reporter system (EXSISERS) into p53 for the study of differential protein-isoform expression

Abstract
HTML

P 4.07

Bauer, Magdalena; Michalski, Marlen; Müller-Schilling, Martina; Gülow, Karsten: Combination of Mcl-1 (Myeloid-Cell Leukemia 1) and Bcl-2 (B-Cell Lymphoma 2) inhibition – A novel treatment approach for Hepatocellular Carcinoma (HCC)

Abstract
HTML

P 4.08

Fuchs, Juri; Murtha-Lemekhova, Anastasia; Kessler, Markus; Guenther, Patrick; Fichtner, Alexander; Pfeiffenberger, Jan; Probst, Pascal; Hoffmann, Katrin: Biliary Rhabdomyosarcoma in Pediatric Patients: A Systematic Review and Meta-Analysis of Individual Patient Data

Abstract
HTML

P 4.09

Wirtz, TheresaHildegard; Brandt, ElisaFabiana; Fischer, Petra; Holland, Christian; Röth, Anjali; Baues, Maike; May, Jan-Niklas; Koehncke, Janine; Ritz, Thomas; Lammers, Twan; Longerich, Thomas; Trautwein, Christian; Berres, Marie-Luise: Novel short-termed mouse model of intrahepatic cholangiocarcinoma by orthotopic transplantation of Hep-55.1C in mice with human homology

Abstract
HTML

P 4.10

Ament, Cindy; Steinmann, Sara; Evert, Matthias; Utpatel, Kirsten; Calvisi, Diego; Evert, Katja: Pathogenetic role of aberrant fucosylation in intrahepatic cholangiocarcinoma

Abstract
HTML

P 4.11

Hajduk, Jovana; Becker, Diana; Heinrich, Sophia; Czauderna, Carolin; Castven, Darko; Straub, Beate; Grimminger, Peter; Galle, Peter; Weinmann, Arndt; Marquardt, Jens: 14-3-3 scaffold protein family as a potential molecular driver of sorafenib resistance in HCC patients

Abstract
HTML

P 4.12

Albrecht, Thomas; Goeppert, Benjamin; Brinkmann, Fritz; Charbel, Alphonse; Zhang, Qiangnu; Schreck, Johannes; Singer, Stephan; Köhler, BrunoChristian; Springfeld, Christoph; Mehrabi, Arianeb; Schirmacher, Peter; Kühl, AnjaAndrea; Vogel, MonikaNadja; Utku, Nalân; Roessler, Stephanie: Intraepithelial TIRC7+ immune cells are positive prognosticators in cholangiocarcinoma and represent a potential target for immunotherapy

Abstract
HTML

P 4.13

Eisner, Ulrike; Sommer, Judith; Thasler, Wolfgang; Bosserhoff, Anja; Hellerbrand, Claus: Role of enhanced bone morphogenetic protein-endothelial cell-precursor derived regulator in hepatocellular carcinoma

Abstract
HTML

P 4.14

Schlosser, Sophie; Aichner, Elisabeth; Ruttmann, Kirstin; Albaladejo-Fuertes, Sheila; Gülow, Karsten; Kunst, Claudia; Müller-Schilling, Martina: Interprofessionelle Ausbildungsstation Regensburg (A-STAR) mit gastroenterologisch-hepatologischem Schwerpunkt – Versorgungsqualität aus Sicht der Patienten

Abstract
HTML

P 4.15

Luo, Xufeng; Liang, Yaojie; Zhang, Rui; Schefczyk, Stefan; Liu, Shi; Baba, HideoA.; Lange, Christian; Wedemeyer, Heiner; Lu, Mengji; Bröring, Ruth: Hepatitis B surface antigen induces nuclear accumulation of YAP, thereby driving BMI1-associated hepatocarcinogenesis

Abstract
HTML

P 4.16

Ganjian, Noujan; Abadi, Zahra; Trompak, Omelyan; Geffers, Robert; Zender, Lars; Pellegrino, Rossella; Longerich, Thomas: Identification and validation of a plasticity driver of Combined Hepatocellular-Cholangiocarcinoma using functional interspecies comparison

Abstract
HTML

P 4.17

Liang, Yaojie; Luo, Xufeng; Schefczyk, Stefan; Baba, HideoA.; Hardtke-Wolenski, Matthias; Schmidt, Hartmut; Bröring, Ruth: Hepatitis B surface antigen induces endoplasmic reticulum stress, impairs autophagy and promotes proliferation, thereby driving hepatocarcinogenesis

Abstract
HTML

P 4.18

Keßler, AnnikaSophia; Nader, Luisa; Scherr, Anna-Lena; Schmitt, Nathalie; Breuhahn, Kai; Weiler, Sofia; Luiken, Sarah; Rössler, Stephanie; Gärtner, Ulrike; Schirmacher, Peter; Heikenwälder, Mathias; Goeppert, Benjamin; Jäger, Dirk; Köhler, BrunoChristian: Non-canonical NF-κB signaling induces proliferation in primary liver cancer

Abstract
HTML

P 4.19

Scheiter, Alexander; Evert, Matthias; Calvisi, Diego; Evert, Katja; Utpatel, Kirsten: Galectin-1 upregulation in PIK3CA induced hepatocarcinogenesis- therapeutic cooperativity

Abstract
HTML

P 4.20

Seitz, Tatjana; Freese, Kim; Sommer, Judith; Thasler, WolfgangErwin; Hellerbrand, Claus: Expression of fibroblast growth factor receptors in hepatocellular carcinoma

Abstract
HTML

P 4.21

Seitz, Tatjana; John, Nora; Bosserhoff, AnjaK.; Hellerbrand, Claus: Crosstalk of hepatic stellate cells and uveal melanoma cells in the liver metastatic niche

Abstract
HTML

P 4.22

Fründt, Thorben; Casar, Christian; von Felden, Johan; Krause, Jenny; Gil-Ibanez, Ines; Schöler, Ulrike; Priebe, Maximillian; Adam, Gerhard; Huber, Samuel; Lohse, Ansgar; Wege, Henning; Schulze, Kornelius: Equal overall survival in elderly patients with hepatocellular carcinoma and liver cirrhosis receiving palliative treatment.

Abstract
HTML

P 4.23

John, Katharina; Busche, Stephanie; Wandrer, Franziska; Wedemeyer, Heiner; Schulze-Osthoff, Klaus; Bantel, Heike: Apoptosis sensitivity of hepatocellular carcinoma to sorafenib-based treatment combinations depends on the expression pattern of BH3-only proteins

Abstract
HTML

P 4.24

Sommer, Judith; Hellerbrand, Claus: Expression of growth differentiation factor 5 in liver disease and cancer

Abstract
HTML

P 4.25

von Bubnoff, Fabian; Wesener, Marie; Schmitt, Jennifer; Ruppert, Thomas; Schirmacher, Peter; Breuhahn, Kai; Weiler, Sofia: Direct interaction of the oncogenes YAP and TAZ with the transcription factor HNF1B in hepatocellular carcinoma

Abstract
HTML

P 4.26

Sagmeister, Paula; Daza, Jimmy; Ofner, Andrea; Ziesch, Andreas; Ye, Liangtao; Ben-Khaled, Najib; Reiter, FlorianP; Ebert, Matthias; Mayerle, Julia; Teufel, Andreas; De Toni, EnricoN.; Munker, StefanM: Comparative response of HCC cells to sorafenib, lenvatinib, cabozantinib and regorafenib; descriptive expression analysis

Abstract
HTML

P 4.27

Rupp, Carina; Rösner, Thomas; Bauer, Ulrike; Kohnke-Ertel, Birgit; Lechler, Christian; Manmadhan, Saumya; Steiger, Katja; Mogler, Carolin; Becker, Diana; Marquardt, Jens; Engleitner, Thomas; Rad, Roland; Saur, Dieter; Schmid, Roland; Ehmer, Ursula: Relevance of MEK/ERK signaling in biliary differentiation in murine liver cancer

Abstract
HTML

P 4.28

Lin, Tao; Liu, Heng; Lindquist, Jon; Mertens, Peter; Ebert, Matthias; Dooley, Steven; Li, Jun; Munker, Stefan; Weng, Honglei: Cold shock protein YB-1 upregulates MDR1 transcription and thus contributes to cholangiocarcinoma chemoresistance to cisplatin

Abstract
HTML

P 4.29

de Castro, Tiago; Jochheim, Leonie; Bathon, Melanie; Welland, Sabrina; Jeschke, Matthias; Ludwig, JohannesM.; Lange, ChristianM.; Saborowski, Anna; Vogel, Arndt: Atezolizumab and bevacizumab in patients with advanced hepatocellular carcinoma with impaired liver function and prior systemic therapy – a real-world experience

Abstract
HTML

P 4.30

Janzen, Jakob; Ranvir, VikasPrakasch; Ramos, TaniaAraujo; Pfister, Dominik; Frick, Lukas; Garcia-Beccaria, Maria; Rubio, Karla; Barreto, Guillermo; Rössler, Stephanie; Goeppert, Benjamin; Rahbari, Nuh; Golriz, Mohammad; Mehrabi, Arianeb; Helm, Dominic; Poschet, Gernot; Klinke, GlynisFiona; Tschaharganeh, Darjus; Weber, Achim; Heikenwälder, Mathias; Singh, Indrabahadur: In-depth analysis of High-mobility group A proteins in NASH-HCC

Abstract
HTML

P 4.31

Henriquez, JoaquinAraos; Cai, Chen; Zhou, Qianwen; Zheng, Yuwei; Gaitantzi, Haristi; Itzel, Timo; Teufel, Andreas; JAC, LukasHawinkels; Birgin, Emrullah; Ebert, Matthias; Rahbari, Nuh; Breitkopf-Heinlein, Katja: Tumour-suppressive BMP-9 signalling in HCC

Abstract
HTML

P 4.32

Qian, Yuquan; Itzel, Timo; Ebert, MatthiasP.A.; Teufel, Andreas: Deep view on HCC gene signatures: and their comparison with other cancers

Abstract
HTML

P 5.01

Wrobel, Sarah; Russ, Lena; von Bülow, Verena; Quack, Thomas; Grevelding, ChristophG.; Roderfeld, Martin; Roeb, Elke: Infection grade determines intestinal immune reaction in Schistosomiasis

Abstract
HTML

P 5.02

Tran, CongSi; Kersten, Julia; Diehl, Stefan; Breinig, Marco; Colasanti, Ombretta; Fleischmann-Mundt, Bettina; Peter, Malin; Heuss, Christian; Faure-Dupuy, Suzanne; Riedl, Tobias; Mutz, Pascal; Poth, Tanja; Schirmacher, Peter; Bartenschlager, Ralf; Kühnel, Florian; Heikenwälder, Mathias; Tschaharganeh, Darjus; Lohmann, Volker: Contribution of the Cellular Lipid Kinase PI4KA to HCV-induced Liver Pathogenesis

Abstract
HTML

P 5.03

Knodel, MarkusM.; Nägel, Arne; Grillo, Alfio; Herrmann, Eva; Wittum, Gabriel: 3D spatially resolved HCV replication models simulated at realistic cell geometries

Abstract
HTML

P 5.04

Ohlendorf, Valerie; Wübbolding, Maximilian; Bremer, Birgit; Siederdissen, ChristophHönerzu; Wedemeyer, Heiner; Cornberg, Markus; Maasoumy, Benjamin: Association between low anti-HBc level and lower risk of virological relapse after nucleos(t)ide analogue cessation in HBe antigen negative chronic hepatitis B patients

Abstract
HTML

P 5.05

Schefczyk, Stefan; Merz, Simon; Luo, Xufeng; Trippler, Martin; Hardtke-Wolenski, Matthias; Schmidt, Hartmut; Bröring, Ruth: Production and release of hepatitis B virus particles in a 1.4-transgenic mouse model lead to increased phagocytic activity in Kupffer cells

Abstract
HTML

P 5.06

Schefczyk, Stefan; Luo, Xufeng; Trippler, Martin; Walkenfort, Bernd; Hasenberg, Mike; Lu, Mengji; Schmidt, Hartmut; Bröring, Ruth: Hepatitis B virus-replicating transgenic mice exhibit a functional but altered responsiveness to Tlr3 and Rig-I activation

Abstract
HTML

P 5.07

Zigmond, Ehud; Zecher, BrittaFranziska; Bartels, Anna-Lena; Ziv-Baran, Tomer; Rösch, Thomas; Schachschal, Guido; Lohse, AnsgarW.; Ehlken, Hanno; Schramm, Christoph: Colonisation of bile ducts with Enterococcus sp. associates with the prognosis of Primary Sclerosing Cholangitis

Abstract
HTML

P 5.08

Gottwick, Cornelia; Krzikalla, Daria; Mesquita, LígiaMargaridaMarques; Mancini, Federica; Fanzutti, Marco; Digigow, Reinaldo; Lohse, AnsgarW.; Carambia, Antonella; Herkel, Johannes: Liver fibrosis does not impair tolerance induction by liver sinusoidal endothelial cells in vivo

Abstract
HTML

P 5.09

Esegh, AmjadAlhyari; Gehring, Sonja; Knapp, Niklas; Gress, ThomasMathias: Acute Cytomegalovirus (CMV) Hepatitis in an Immunocompetent Female, A Case Report and Review of Literature

Abstract
HTML

P 5.10

Basic, Michael; Wu, Qingyan; Schollmeier, Anja; Sarrazin, Christoph; Zeuzem, Stefan; Hildt, Eberhard; Peiffer, Kai-Henrik: Comprehensive analysis of different phases of chronic Hepatitis B Infection

Abstract
HTML

P 5.11

Russ, Lena; von Bülow, Verena; Hehr, Laura; Wrobel, Sarah; Wirth, Victoria; Tabatabai, Kuscha; Schramm, Gabriele; Quack, Thomas; Grevelding, ChristophG.; Roderfeld, Martin; Roeb, Elke: Th2 immune response correlates inversely with the egg load in S. mansoni infection

Abstract
HTML

P 5.12

Christoph, Sandra; Gerken, Guido; Schmidt, Hartmut; Kahraman, Alisan: A patient with congenital hepatic fibrosis, after living-donor liver transplantation, developed a systemic IgG4-related disease following infection with SARS-CoV-2

Abstract
HTML

P 5.13

Winkler, Frances; Hipp, Anna; Martin, Bianca; Gorka, Oliver; Groß, Olaf; Hofmann, Maike; Thimme, Robert; Bengsch, Bertram: Enolase represents a metabolic checkpoint controlling the differential exhaustion of virus-specific CD8+ T cells in viral hepatitis

Abstract
HTML

P 5.14

Bahn, Jonas; Kunzmann, LillyK.; Steinmann, Silja; Müller, Christian; Sebode, Marcial; Lohse, AnsgarW.; Huber, Samuel; Schwinge, Dorothee; Schramm, Christoph; Poch, Tobias: A polymorphism at the BACH2 locus associates with skewed T cell differentiation in patients with primary sclerosing cholangitis

Abstract
HTML

P 5.15

Khanal, Rajendra; Heinen, Natalie; Bogomolova, Alexandra; Wedemeyer, Heiner; Ott, Michael; Pfaender, Stephanie; Sharma, AmarDeep: MicroRNAs modulate SARS-CoV-2 infection in primary human hepatocytes by regulating the entry factors ACE2 and TMPRSS2

Abstract
HTML

P 5.16

Killer, Alexander; Bock, Hans; Lüdde, Tom; Ghavami, Mahyar; Timm, Jörg; Lübke, Nadine; Walker, Andreas: Reality Check: Bulevirtide for HBV/HDV coinfection, dynamics of virological parameters and liver-stiffness

Abstract
HTML

P 5.17

Guillot, Adrien; Winkler, Marc; Kohlhepp, MarleneSophia; Tacke, Frank: Exploring the potential of multiplex immunohistochemistry to unravel histological and immunological changes during non-alcoholic steatohepatitis and primary sclerosing cholangitis in human and mouse liver

Abstract
HTML

P 5.18

Dudek, Michael; Knolle, Percy; Pfister, Dominik; Heikenwälder, Mathias; Donakonda, Sainitin; Laschinger, Melanie; Hartmann, Daniel; Hüser, Norbert; Sebode, Marcial; Filpe, Pamela; Rad, Roland; Öllinger, Rupert; Roth, Susanne; Mallm, Jan-Philipp; Müller-Stich, Beat; Billeter, Adrian; Tilg, Herbert; Reider, Simon: Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH

Abstract
HTML

P 5.19

Jonin, Fitriasari; Rumer, Charlotte; Tiegs, Gisa; Neumann, Katrin: Expression of inflammatory, immune regulatory and tissue restorative genes by both Ly6Chi and Ly6Cint/- monocyte/macrophage subsets in acute and chronic liver injury in mice

Abstract
HTML

P 5.20

Peiseler, Moritz; Demske, Catharina; Werner, Wiebke; Hammerich, Linda; Tacke, Frank; Heymann, Felix: Tim4high expression identifies a Kupffer cell subset with enhanced catching proficiency

Abstract
HTML

P 5.21

Wachtendorf, Selina; Tiegs, Gisa; Neumann, Katrin: The IL-33/amphiregulin axis mediates immunoregulation in acute and chronic liver disease

Abstract
HTML

P 5.22

Hartl, Johannes; Kroll, Claudia; Stahl, Felix; Lohse, AnsgarW.; Christoph, Schramm; Sebode, Marcial: Serological and clinical features of primary biliary cholangitis in first degree relatives: a prospective cohort study.

Abstract
HTML

P 5.23

Kellerer, Mareike; Horst, Andrea: CD5-mediated mTOR inhibition on T cells through binding of soluble CEACAM1

Abstract
HTML

P 5.24

Bruneau, Alix; Lurje, Isabella; Hammerich, Linda; Guillot, Adrien; Tacke, Frank: Immune cell composition in cholangiopathies: Target and modulator of gut-to-liver signals in cholestatic liver injury

Abstract
HTML

P 5.25

Csernalabics, Benedikt; Boettler, Tobias; Salié, Henrike; Luxenburger, Hendrik; Wischer, Lara; Zoldan, Kathrarina; Krimmel, Laurenz; Bronsert, Peter; Schwabenland, Marius; Prinz, Marco; Mogler, Carolin; Neumann-Haefelin, Christoph; Thimme, Robert; Hofmann, Maike; Bengsch, Bertram: Immune-mediated Hepatitis associated with SARS-CoV-2 mRNA vaccination

Abstract
HTML

P 5.26

Bosch, Miriam; Kallin, Nina; Donakonda, SainitinDonakondaSainitin; Protzer, Ulrike; Zehn, Dietmar; Wohlleber, Dirk; Knolle, Percy: Dysfunctional liver-resident CXCR6+ CD8 T cells during persistent viral liver infection

Abstract
HTML

P 5.27

Volz, Tassilo; Lempp, Florian; Cameroni, Elisabetta; Passini, Nadia; Urban, Stephan; Corti, Davide; Schmid, MichaelA.; Dandri, Maura: Pre-clinical characterization of an HBsAg-specific monoclonal antibody preventing HBV spreading and reducing HBV, HDV and HBsAg in serum of humanized mice

Abstract
HTML

P 5.28

Oltmanns, Carlos; Mischke, Jasmin; Tauwaldt, Jan; Kraft, AnkeR.M.; Wedemeyer, Heiner; Cornberg, Markus; Xu, Cheng-Jian: Reverse Inflammaging: Biological age is accelerated in chronic HCV patients and decelerates after HCV cure

Abstract
HTML

P 5.29

Du, Yanqin; Khera, Tanvi; Strunz, Benedikt; Deterding, Katja; Todt, Daniel; Hardtke, Svenja; Port, Kerstin; Ponzetta, Andrea; Steinmann, Eike; Cornberg, Markus; Hengst, Julia; Björkström, NiklasK.; Wedemeyer, Heiner: Imprint of unconventional T cell response in acute hepatitis C persists despite successful early antiviral treatment

Abstract
HTML

P 5.30

Lang-Meli, Julia; Luxenburger, Hendrik; Karl, Vivien; Alizei, ElaheSalimi; Csernalabics, Benedikt; Oberhardt, Valerie; Bengsch, Bertram; Böttler, Tobias; Thimme, Robert; Hofmann, Maike; Neumann-Haefelin, Christoph: SARS-CoV-2-specific adaptive immune response after mRNA vaccination in liver transplanted patients

Abstract
HTML

P 5.31

Calaminus, Moritz; Giersch, Katja; Volz, Tassilo; Pirosu, Andrea; Lütgehetmann, Marc; Dandri, Maura; Allweiss, Lena: Therapeutic shutdown of HBV transcripts promotes reappearance of the SMC5/6 complex and cccDNA silencing in vivo without affecting posttranslational modifications of cccDNA-bound histones

Abstract
HTML

P 5.32

Stindt, Sabine; Luedde, Tom; Bode, JohannesG.: HCV modifies the expression of the ErbB ligands NRG1 and EGF in a Sp1-dependent manner

Abstract
HTML

P 5.33

Zehentmeier, Maria; Ambike, Shubhankar; Protzer, Ulrike; Michler, Thomas: Unravelling the role of hepatocytes in hepatitis B virus specific immunotolerance

Abstract
HTML

Subscribe to RSS

Zeitschrift für Gastroenterologie