DOI: 10.1055/s-00000131

Synfacts

Issue 11 · Volume 13 · November 2017 DOI: 10.1055/s-007-35124

Synform

A177
Zanda, Matteo: SYNFORM ISSUE 2017/11

Synthesis of Natural Products and Potential Drugs

z1111
All PDFs of this category
1111
Commercial Synthesis of BMS-663068
1112
Development of a Commercial Synthesis of BMS-663068
1113
Synthesis of Vismodegib via Directed C–H Chlorination
1114
Syntheses of Tetracenomycins C and X
1115
Total Synthesis of (±)-Hippolachnin A
1116
Synthesis of Letermovir via Asymmetric Hydrogen Bonding Catalysis
1117
Synthesis of Atorvastatin via NHC-Catalyzed Three-Component Coupling
1118
Enantioselective Synthesis of (–)-Vindorosine
1119
Total Synthesis of (–)-Crotogoudin
1120
Total Syntheses of Mulinane Diterpenoids
1121
Syntheses of Curcusone I and J
1122
Formal Synthesis of Omarigliptin
1123
Synthesis of (–)-Spiroxin C
1124
Synthesis of BRD3914 via Directed C(sp3)–H Arylation

Synthesis of Heterocycles

z1125
All PDFs of this category
1125
Oxidative C–H Sulfenylation of Carbonyls
1126
Difluoromethylation of Aryl- or Hetarylboronic Acids and Esters
1127
Enantioselective Modular Approach to 3-Azabicyclohexanes
1128
Synthesis of Pyrrolocoumarins and Substituted Pyrroles
1129
Oxetanones and Azetidinones for the Synthesis of 6-Azaspiro[4.3]octanes
1130
Synthesis of Indoles by Ruthenium-Catalyzed C–H Activation
1131
Synthesis of 2-Allyl-3-oxazolin-5-ones and Trisubstituted Pyridines
1132
Ethyl Tertiary Amines as a Carbon Source in Imidazopyridines Synthesis
1133
Rhodium-Catalyzed Cyclizations of Enoldiazoacetamides with Nitrosoarenes
1134
2′-Homoazanucleosides by Ring-Closing Metathesis
1135
Selective N-Methylation of Pyrimidone with Chloro(chloromethyl)dimethylsilane–KF
1136
Synthesis of Trifluoromethylated Pyrido[2,3-d]pyrimidinediones
1137
Synthesis of Trifluoromethylated Heterocycles from N-Carbamoyl Imines
1138
Synthesis of Quinazoline-2,4(1H,3H)-diones from 2-Iodoanilines
1139
Three-Component Synthesis of Benzopyrans from δ-Acetoxy Allenoates

Synthesis of Materials and Unnatural Products

z1141
All PDFs of this category
1141
Simple Selective Strategy to Stars
1142
A Radical Move Forward in Perfluoroalkoxylation
1143
Magic Additive for intermolecular Pauson–Khand Reactions
1144
Materials Liquefied by Light
1145
Making Diversity Click
1146
A ‘Swiss Army Knife’ Polymer
1147
Novel N-Heteroheptacenes for OFET Devices
1148
Fair Trade Synthesis: An ‘I’ for an ‘SO2’
1149
Extended Enantiospecific Helicenes
1150
Twisting up Peropyrene
1151
Toward Longer Phenacenes
1152
For Electronics – Acetylenic Linkage Length Matters

Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions

z1153
All PDFs of this category
1153
Ruthenium-Catalyzed Cycloaddition of Benzocyclobutenones with Diols
1154
Enantioselective Cyanation of Oxindoles
1155
Copper-Catalyzed Hydroarylation Reaction
1156
Indium-Catalyzed Enantioselective [4+2] Annulation
1157
A Gold-Catalyzed Rearrangement/Cyclization Cascade
1158
Chiral Gold(III) Complex-Catalyzed Kinetic Resolution of 1,5-Enynes
1159
Formation of Cyclobutanones by Cobalt-Catalyzed Hydroacylation
1160
Rhodium-Catalyzed Asymmetric Coupling of Indoles with Alkynes
1161
Zinc-Catalyzed Regio- and Enantioselective N-Alkylation of Indole
1162
Iridium-Catalyzed Asymmetric Synthesis of Cyclic Amines
1163
Intramolecular Desymmetrization by C–H Silylation with Iridium Catalysts
1164
Catalytic Asymmetric Michael Addition Reaction of Tertiary Enolates
1165
Rhodium-Catalyzed Asymmetric Synthesis of Phosphonic Acids
1166
Rhodium-Catalyzed Asymmetric Hydrogenation of Enones
1167
Nickel-Catalyzed Conjugate Addition of Silyl Ketene Imines to Indol-2-ones
1168
Asymmetric Ring Opening of Aziridines Using a Chiral Magnesium Complex
1169
Copper-Catalyzed Asymmetric Conjugate Addition of Alkylzirconium Reagents
1170
Rhodium-Catalyzed O–H Insertion into Carboxylic Acids or Alcohols
1171
Stereospecific Nickel-Catalyzed Suzuki–Miyaura Cross-Coupling Reaction
1172
Lewis Acid Catalyzed Enantioselective Photocycloaddition
1173
Nickel-Catalyzed Stereoselective Ring-Opening Reaction
1174
Synthesis of Tetrahydropyrrolo[1,2-a]pyr-azines by Asymmetric Hydrogenation
1175
Iron-Catalyzed Enantioselective Hydrogenation of 1,2-Diketones
1176
Synthesis of Chiral γ-Phosphono-α-Amino Acids by C–H Alkylation
1177
Manganese-Catalyzed Asymmetric Epoxidation of Electron-Deficient Alkynes
1178
Palladium-Catalyzed Synthesis of Carbocycles
1179
Stereoselective Synthesis of Allylamines from Trichloroacetimidates
1180
Asymmetric Synthesis of γ-Amino Esters by Palladium-Catalyzed Allylic Amination
1181
Cobalt-Catalyzed Regioselective C–H Activation of Amides with Alkynes
1182
Silver-Catalyzed Diastereoselective and Enantioselective Michael Addition

Metal-Mediated Synthesis

z1183
1183
β,γ-Dicarbofunctionalization of Alkenyl Carbonyl Compounds
1184
Synthesis of Aldehydes with All-Carbon α-Quaternary Centers
1185
Addition of Halolithium Carbenoids to Weinreb Amides and N-Acylpyrroles
1186
α-Perfluoroalkyl-β-Alkynylation of Alkenes
1187
Electrophilic Amination with Nitroarenes
1188
Copper-Catalyzed Synthesis of 2,3-Allenols and Alkenes by Using Propargyl Epoxides
1189
Suzuki–Miyaura Cross-Coupling of Amides and Esters
1190
Palladium-Catalyzed α,β-Dehydrogenation of Carboxylic Acids
1191
Intermolecular Exchange between C–C and C–Si σ-Bonds
1192
Synthesis of α-Quarternary Carboxylic Acid Derivatives
1193
Asymmetric Synthesis of Tertiary Alcohols and Thiols
1194
Silver-Catalyzed Decarboxylative Trifluoromethylation
1195
Cyclizations and Cyclization Cascades of Samarium Ketyl Radicals
1196
Nickel-Catalyzed Cross-Coupling of 9-BBN-Borates
1197
Decarboxylative Alkynylation of N-Hydroxyphthalimide Esters

Organo- and Biocatalysis

z1199
All PDFs of this category
1199
Cyclobutadienes via an Organocascade
1200
Flavin-Dependent Ene-Reductase-Catalyzed Hydrogen Atom Transfer
1201
Simple Nucleophiles for α,β-Unsaturated Acyl Ammonium Catalysis
1202
Chiral Biphenyl-Based Thiourea/Amine Catalyst for the Henry Reaction
1203
Enantioselective cis-Aziridination of α,β-Unsaturated Aldehydes
1204
Methanobenzo[7]annulene Synthesis by Asymmetric [3+2] Cycloaddition
1205
Oxidative Photoredox-Catalyzed Imino-Functionalizations of Olefins
1206
Enantioselective Synthesis of Nitriles by Enzymatic Dehydration of Oximes
1207
Elucidating the Biosynthetic Mechanism toward the Quinaldic Acid Moiety

Polymer-Supported Synthesis

z1209
All PDFs of this category
1209
Reductive Amination of Carbonyl Compounds on Nb2O5-Supported Ruthenium
1210
Mild Hydrogenation of Amides to Amines on Platinum–Vanadium Nanoparticles
1211
1,4-Addition of Glycine Derivatives to α,β-Unsaturated Esters by Using CsF·Al2O3
1212
Synthesis of Isoxazole-5-(4H)-ones with Sulfated Polyborate
1213
Photocatalytic Epoxidation of Alkenes on TiN-Supported Cu Nanoparticles
1214
Carbonylative Amidation Catalyzed by Palladium Nanoparticles Formed in situ
1215
Selective Photooxidation of Alcohols on a Covalent Triazine Framework
1216
Silica-Supported Tungstic Acid Catalyst for a Three-Component Condensation
1217
Cobalt Nanoparticle-Catalyzed Transfer Hydrogenation of N-Heteroarenes
1218
Palladium-Catalyzed Aminocarbonylation of Aryl Iodides
1219
One-Pot Synthesis of Coumarin-Fused Triazolopyrimidines with P-MCM-41
1220
Suzuki–Miyaura Coupling on Fe3O4@SiO2-Supported Palladium
1221
Hydrosilylation of Olefins on a Silica-Supported Rhodium/Amine Catalyst
1222
Aerobic Photooxidation of Alcohols on a Palladium/Titanium Cluster Catalyst
1223
Palladium-Catalyzed β-Amino Alcohol Synthesis from Anilines and Ethylene Glycol
1224
Preparation of Monoalkynylpiperidines by Mild Hydrogenation