DOI: 10.1055/s-00000175

Arzneimittelforschung

Ausgabe 02 · Volume 50 · Februar 2000 DOI: 10.1055/s-002-22697

CNS-active Drugs · Hypnotics · Psychotropics · Sedatives

99
Lintz, Wolfgang; Becker, Reinhard; Gerloff, Joachim; Terlinden, Rolf: Pharmacokinetics of Tramadol and Bioavailability of Enteral Tramadol Formulations
4th Communication: Drops (without ethanol)

Anticoagulants · Antithrombotics · Antivaricosis Drugs Blood Flow Stimulants

109
Kiesewetter, Holger; Koscielny, Jürgen; Kalus, Ulrich; Vix, Jean-Michel; Peil, Hubertus; Petrini, Orlando; Toor, Bert S J van; Mey, Christian de: Efficacy of Orally Administered Extract of Red Vine Leaf AS 195 (folia vitis viniferae) in Chronic Venous Insufficiency (Stages l-ll)

Lipid Reducers

118
Tsutsumi, Kazuhiko; Inoue, Yasuhide; Murase, Toshio: Effects of NO-1886, a Lipoprotein Lipase Promoting Agent, on Homozygous and Heterozygous Watanabe Heritable Hyperlipidaemic Rabbits

Antidiabetics

122
Koreca, Rudolf; Senschb, Karl Heinz; Zoukasb, Thomas: Effects of the Neoflavonoid Coutareagenin, One of the Antidiabetic Active Substances of Hintonia latiflora, on Streptozotocin-induced Diabetes mellitus in Rats

Liver Therapeutics

129
Scaliaa, Santo; Scagliarinib, Raffaella; Pazzib, Paolo: Evaluation of Ursodeoxycholic Acid Bioavailability from Immediate- and Sustained-release Preparations Using Gas Chromatography-Mass Spectrometry and High-performance Liquid Chromatography

Analgesics · Antiphlogistics · Antirheumatic Drugs

135
Graßmanna, Johanna; Hippelia, Susanne; Dornischa, Kerstin; Rohnerta, Ute; Beuscherb, Norbert; Elstnera, Erich F: Antioxidant Properties of Essential Oils

Originalarbeit

140
Bruno, Olga; Schenone, Silvia; Ranise, Angelo; Barocelli, Elisabetta; Chiavarini, Milena; Ballabeni, Vigilio; Bertoni, Simona: Synthesis and Pharmacological Screening of Novel Non-acidic Gastroprotective Antipyretic Anti-inflammatory Agents with Anti-platelet Properties
148
Omata, Takeshi; Itokazu, Yoshihiko; Inoue, Naonori; Segawa, Yoshihide: Effects of Chondroitin Sulfate-C on Articular Cartilage Destruction in Murine Collagen-induced Arthritis
158
Enanga, Bertin; Ndong, Jerôme Mezui Me; Boudra, Hamid; Debrauwer, Laurent; Dubreuil, Guy; Bouteille, Bernard; Chauvière, Gérard; Labat, Christian; Dumas, Michel; Périé, Jacques; Houin, Georges: Pharmacokinetics, Metabolism and Excretion of Megazol in a Trypanosoma brucei gambiense Primate Model of Human African Trypanosomiasis
163
Khalifa, Latifa; Rosales, Maria-José; Mascaro, Carmen; Karolak-Wojciechowska, Janina; Bsiri, Nadia; Brouant, Pierre; Barbe, Jacques: Inhibition of Cryptosporidium parvum in vitro by 9-(Alkylthio)acridine Derivatives
167
Gürsoy, Aysel; Karalı, Nilgün: 4-(3-Coumarinyl)-4-thiazolin-2-one Benzylidene-hydrazones with Antituberculosis Activity
173
Nessim, Nevine G; Demerdash, Zeinab: Correlation between Infection Intensity, Serum Immunoglobulin Profile, Cellular Immunity and the Efficacy of Treatment with Praziquantel in Murine Schistosomiasis mansoni
191
Scriba, Peter C: Einführung in das Thema
193
Manger, Bernhard: Cyclosporin A in der Therapie von Autoimmunerkrankungen des rheumatischen Formenkreises
194
Smolen, Josef S: Leflunomid bei der rheumatoiden Arthritis
196
Ruzicka, Thomas: Tacrolimus in Immune-mediated Skin Diseases
197
Kalden, Joachim R: Anti-Tumor-Nekrose-Faktor-Therapie bei der rheumatoiden Arthritis
198
Zeitz, Martin: Anti-Tumor-Nekrose-Faktor-Antikörper bei Patienten mit Morbus Crohn
200
Endres, Stefan; Siegmund, Britta; Hartmann, Gunther; Eigler, Andreas: Pharmakologische Suppression der Synthese von Tumor-Nekrose-Faktor
203
Schudt, Christian: Selektive Phosphodiesterase-Hemmer als potentielle Suppressoren chronischer Entzündungen
205
Kurrle, Roland: Interleukin-1 Converting Enzyme (ICE) als therapeutischer Angriffspunkt
206
Mayet, Werner J: Neue Therapiekonzepte bei Morbus Wegener
208
Lehr, Claus-Michael: Kontrolle von Wirkstofftransport über biologische Barrieren
210
Wildner, Gerhild: Orale Toleranzinduktion bei Autoimmunuveitis
212
Dahlke, Frank: Interferon-β-Behandlung der Multiplen Sklerose
214
Pap, Thomas; Gay, E; Gay, Steffen: Stand der Gentherapie bei Rheumatoid Arthritis
215
Eigler, Andreas; Dauer, Marc; Schulze, Johannes: Klinische Pharmakogenetik: Polymorphismus der Thiopurinmethyltransferase und Therapie mit Azathioprin
216
Fokko, Woude J van der: New Concepts for Chronic Rejection after Solid Organ Transplantation
217
Brinkmann, Volker: FTY720, a Novel Class Immunosuppressant that Modulates Lymphocyte Recirculation
219
Müller, Peter; Rothlein, Robert: Potential of Leukocyte Adhesion Antagonists as Immunosuppressives
220
Haller, Hermann: Anti-ICAM-1-Antisense-Therapie bei Nierentransplantation
221
Neuhaus, Peter; Langrehr, Jan M: Unterschiedliche Immunsuppressionsschemata bei der Lebertransplantation
223
Claus, Hammer: Xenotransplantation: Hoffnung oder Irrweg?
225
Anschriften der Referenten
226
Book Reviews

Antibacterials · Antibiotics · Chemotherapeutics · Cytostatics

154
Ayhan-Kilcigil, Gülgün; Altanlar, Nurten: Synthesis of 3-Substituted Phenacyl-5-[2-phenyl-4H-4-oxo-1-benzopyran-6-yl)methylenyl]-thiazolidine-2,4-diones and Evaluation of Their Antimicrobial Activity

Immunomodulators · Immunostimulants · Immunosuppressants

178
Borghardt, Jürgen; Rosien, Bernd; Görtelmeyer, Roman; Lindemann, Svenja; Hartleb, Martin; Klingmüller, Martin: Effects of a Spleen Peptide Preparation as Supportive Therapy in Inoperable Head and Neck Cancer Patients

Information on Patents

185
Habernickel, Dr.Valentin J: The Pharma Market as Reflected by Patents