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Thromb Haemost 2011; 105(05): 820-827
DOI: 10.1160/TH10-08-0562
Theme Issue Article
Schattauer GmbH

Advances in imaging angiogenesis and inflammation in atherosclerosis

Lyubomir Zagorchev
1   Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA
3   Dartmouth Medical School, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA
4   Philips Research North America, Briarcliff, New York, USA
,
Mary Jo Mulligan-Kehoe
2   Department of Surgery, Vascular Section, Dartmouth Medical School, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA
› Author Affiliations Financial support: Supported in part by National Institutes of Health, National Heart, Lung, and Blood Institute Grant HL-69948 (M. J. Mulligan-Kehoe).
Further Information

Publication History

Received: 31 August 2010

Accepted after major revision: 28 January 2011

Publication Date:
28 November 2017 (online)

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Summary

Advances in imaging technology have provided powerful tools for dissecting the angiogenic and inflammatory aspects of atherosclerosis. Improved technology along with multi-modal approaches has expanded the utilisation of imaging. Recent advances provide the ability to better define structure and development of angiogenic vessels, identify relationships between inflammatory mediators and the vessel wall, validate biological effects of anti-inflammatory and anti-angiogenic drugs, delivery and/or targeting specific molecules to inflammatory regions of atherosclerotic plaques.

Keywords

Atherosclerosis - inflammation - angiogenesis - imaging
 

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