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Synfacts 2008(10): 1090-1090  
DOI: 10.1055/s-2008-1078226
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Cu-Catalyzed Pd-Free Sonogashira-Type Reactions

Contributor(s): Paul Knochel, Andreas J. Wagner
F. Monnier*, F. Turtaut, L. Duroure, M. Taillefer*
École Nationale Supérieure de Chimie de Montpellier, France
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Publication History

Publication Date:
22 September 2008 (online)

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Significance

This work presents a new catalytic system using a readily available copper/ligand combination for a Sonogashira-type cross-coupling reaction between aryl iodides and phenyl- and hexylacetylene which affords disubstituted alkynes in good to excellent yields.