Synlett 2007(7): 1043-1046  
DOI: 10.1055/s-2007-973875
LETTER
© Georg Thieme Verlag Stuttgart · New York

Synthesis of 3-Sulfonyloxypyridines: Oxidative Ring Expansion of α-Furyl­sulfonamides and N→O Sulfonyl Transfer

Robert Hodgsona, Andrew Kennedyb, Adam Nelson*a, Alexis Perry*a
a Department of Chemistry, University of Leeds, Leeds, LS2 9JT, UK
Fax: +44(113)3436565; e-Mail: a.s.nelson@leeds.ac.uk; e-Mail: oldralph@hotmail.co.uk;
b Synthetic Chemistry, Chemical Development, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK
Further Information

Publication History

Received 4 December 2006
Publication Date:
13 April 2007 (online)

Abstract

N-Sulfonyl pyridinones derived from α-furylsulfon­amides may be aromatised with concomitant N→O sulfonyl transfer to produce 3-sulfonyloxypyridines.