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Synlett 2007(5): 0741-0744
DOI: 10.1055/s-2007-970778
DOI: 10.1055/s-2007-970778
LETTER
© Georg Thieme Verlag Stuttgart · New York
Synthesis of 2-Aza-1-cyano-4-hydroxyanthraquinones
Further Information
Received
28 December 2006
Publication Date:
08 March 2007 (online)
Publication History
Publication Date:
08 March 2007 (online)
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Abstract
Phthalide annulation of 2-alkylpyridin-3-ones results in the formation of the unexpected 2-aza-1-cyano-4-hydroxy-anthraquinones, the cyano moiety originating from the 3-cyanophthalide. These compounds hold great potential against Epstein-Barr Virus Early Antigen (EBV-EA) activation and as antimicrobial compounds
Key words
quinones - annulations - antiviral - phthalide - aza-anthraquinones
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