Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000131.xml
Synfacts 2007(8): 0831-0831
DOI: 10.1055/s-2007-968728
DOI: 10.1055/s-2007-968728
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart · New York
Mixed Organobismuth/Dialkylzinc Reagents for Aryl Transfers
I. Sato*, Y. Toyota, N. Asakura
Kwansei Gakuin University, Hyogo, Japan
Further Information
Publication History
Publication Date:
24 July 2007 (online)
Significance
The authors have developed a mixed triarylbismuthane/dialkylzinc system for catalytic aryl transfer to aromatic aldehydes. The organobismuth and dialkylzinc reagents are needed in stoichiometric amounts and the catalytic component is a chiral β-amino alcohol. The reaction is under catalyst control, except in the case of benzaldehyde where the R-configuration is obtained with the S-catalyst. The scope encompasses simple substitutions of the aryl ring of the aldehydes with good to excellent yields and enantioselectivities observed.