Enantiomerically Pure Bis-β-diketones: Valuable Building Blocks for Metallosupramolecular Chemistry

Abstract

A series of enantiomerically pure bis-β-diketone derivatives was prepared by a Claisen-type condensation between protected tartaric acid diesters and several ketones. Hereby the tartaric acid unit is introduced as either a 2,2-dimethyldioxolane or as a 5,6-dimethoxy-5,6-dimethyl-1,4-dioxane derivative. The yields of the Claisen reaction are relatively low, but the starting materials are readily available, so that the one-step procedure leads to the bis-β-diketone derivatives in up to gram quantities.

Key words

Claisen condensation - β-diketone - chirality - ligand

References

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