Synlett 2005(9): 1450-1452  
DOI: 10.1055/s-2005-868493
LETTER
© Georg Thieme Verlag Stuttgart · New York

Tishchenko Reaction Using an Iridium-Ligand Bifunctional Catalyst

Takeyuki Suzuki*, Taichiro Yamada, Tomohito Matsuo, Kazuhiro Watanabe, Tadashi Katoh*
Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-Ku, Sendai, Miyagi 981-8558, Japan
Fax: +81(22)2752013; e-Mail: suzuki-t@tohoku-pharm.ac.jp; e-Mail: katoh@tohoku-pharm.ac.jp;
Further Information

Publication History

Received 8 March 2005
Publication Date:
25 April 2005 (online)

Zoom Image

Abstract

Tishchenko reaction of aldehydes in the presence of an amino alcohol-based Ir bifunctional catalyst was developed. The reaction proceeds with 1 mol% of the catalyst and 20-30 mol% of K2CO3 in acetonitrile at room temperature to give the corresponding dimeric esters in good yield.