Anästhesiol Intensivmed Notfallmed Schmerzther 2003; 38(9): 573-576
DOI: 10.1055/s-2003-41859
Aktuelle Medizin und Forschung
© Georg Thieme Verlag Stuttgart · New York

Extended spectrum beta-Laktamase (ESBL)-vermittelte Antibiotikaresistenz bei gramnegativen Erregern: Was ist in der Intensivmedizin zu beachten?

Extended Spectrum Beta-Lactamse (ESBL)-Induced Antibiotics Resistance in Gram-Negative Agents: What Should be Watched in Intensive Care Medicine?A.  Kola1 , P.  Gastmeier1
  • 1Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Medizinische Hochschule Hannover
Further Information

Publication History

Publication Date:
16 September 2003 (online)

Zusammenfassung

Bei der Therapie von Infektionen, die durch gramnegative Erreger verursacht werden, spielen 3. Generations-Cephalosporine eine wichtige Rolle. Extended spectrum beta-Lactamasen (ESBL) sind in der Lage, diese zu inaktivieren. Da die Zahl der ESBL-produzierenden Erreger weltweit stetig zunimmt, ist es wichtig, das Auftreten von ESBL-Bildnern rechtzeitig zu erkennen, um geeignete Maßnahmen zur Prävention und Therapie ergreifen zu können.

Abstract

Third-generation cephalosporins have an important part in the therapy of infections due to gram-negative bacteria. Extended spectrum beta-lactamases (ESBL) are able to hydrolize these antibiotics. As the number of ESBL-producing bacteria is increasing worldwide, detection of ESBL-producers is important for the both of prevention and therapy.

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Dr. med. Axel Kola

Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Medizinische Hochschule Hannover

Carl-Neuberg-Straße 1

30625 Hannover

Email: kola.axel@mh-hannover.de