Abstract
Reported here is a new procedure for the synthesis of α-arylpropionic acids 1 in the racemic form, starting from derivatives of aromatic carboxylic acids 2 (i.e., esters), via 1-aryl-2,2,2-tris(alkylsulfanyl)ethanones 4 -6 , S -alkyl (aryl)bis(alkylsulfanyl)thioacetates 7-9 , S -alkyl α-aryl-α-(alkylsulfanyl)thiopropionates 10 -12 and S -alkyl α-arylthiopropionates 13 -15 . Each stage takes place easily and yields are always high.
Key words
thioacetates - desulfurizations - thiols - arylpropionic acids - drugs
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