(Chloromethyl)triisopropoxysilane Enables Highly Regioselective N1-Methylation of Pyrazoles

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Synfacts 2024; 20(06): 0649
DOI: 10.1055/s-0043-1773291

Innovative Drug Discovery and Development

Contributor(s):

Antonia F. Stepan (Roche)

,

Thomas R. Puleo (Pfizer)

pyrazoles - heterocycles - methylation - regioselectivity

Article published online:
14 May 2024

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany