Overstitch versus Endomina for endoscopic sleeve gastroplasty

Aims Endoscopic sleeve gastroplasty (ESG) is defined as safe and effective. Several devices for ESG are available, but these have not been compared in terms of weight loss outcomes. Aims were to compare outcomes between the Overstitch (Apollo Endosurgery, Austin, TX) and Endomina system (E-ESG, Endo Tools therapeutics, Belgium) in obese patients that underwent ESG.

Methods We reviewed 42 patients which underwent ESG at our unit from january 2020 to december 2021. Patients were matched between the two groups for age, sex, and body mass index (BMI).

Results The mean age and BMI were 48 years old and 34 kg/m². The majority were female (90.48%). All procedures were performed by the same endoscopic team to avoid operator-related bias. The TBWL% at 12 and 24 months with Overstich were 16% and 10.87% compared to 16.53% and 13.92% with Endomina. The EWL% at 12 and 24 months were 58.94% and 40.24% with Overstich compared to 66.74% and 55.45% with Endomina.

Conclusions Both devices have been shown to be effective for obesity treatment. Endomina appears to have bigger impact in maintaining body weight loss over the long term. Further studies on a larger patient population are needed to better evaluate this data.

Publication History

Article published online:
14 April 2023