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Eur J Pediatr Surg 2023; 33(04): 259-270
DOI: 10.1055/s-0042-1745779
Review Article

Systematic Review of Definitions and Outcome Measures for Postoperative Ileus and Return of Bowel Function after Abdominal Surgery in Children

Laurens D. Eeftinck Schattenkerk 
1   Department of Paediatric Surgery, Emma Children's Hospital, Amsterdam University Medical Center, University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, the Netherlands
2   Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Center, University of Amsterdam, the Netherlands
,
Igor J. Shirinskiy
1   Department of Paediatric Surgery, Emma Children's Hospital, Amsterdam University Medical Center, University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, the Netherlands
,
Gijsbert D. Musters
1   Department of Paediatric Surgery, Emma Children's Hospital, Amsterdam University Medical Center, University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, the Netherlands
,
Wouter J. de Jonge
2   Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Center, University of Amsterdam, the Netherlands
3   Department of General, Visceral, Thoracic and Vascular Surgery, University Hospital Bonn, Bonn, Germany
,
Ralph de Vries
4   Medical Library, Vrije Universiteit, Amsterdam, the Netherlands
,
L.W. Ernest van Heurn
1   Department of Paediatric Surgery, Emma Children's Hospital, Amsterdam University Medical Center, University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, the Netherlands
2   Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Center, University of Amsterdam, the Netherlands
,
Joep P.M. Derikx
1   Department of Paediatric Surgery, Emma Children's Hospital, Amsterdam University Medical Center, University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, the Netherlands
2   Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Center, University of Amsterdam, the Netherlands
› Author Affiliations Funding None.
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Abstract

This review aims to objectify which definitions and outcome measures are used for the return of bowel function and postoperative ileus in children. PubMed and Embase were systematically searched from inception to December 17, 2020. Prospective studies conducted in children (aged 0–18 years) undergoing gastrointestinal surgery which reported on definitions and/or outcome measures for post-operative ileus or return of bowel function were evaluated. Definitions and outcome measures were extracted. From 4,027 references, 71 articles were included. From the 17 articles mentioning postoperative ileus, 8 (47%) provided a definition. In total, 34 outcome measures were used and 12 were unique. “Abdominal distension” was the most reported (41%) measure. In 41%, the outcome measures only described the return of gastric motility, while 18% described the return of intestinal motility. The return of bowel function was mentioned in 67 articles, none provided a definition. In total, 133 outcome measures were used and 37 were unique. Time to oral intake was the most reported (14%) measure. In 49%, the outcome measures only described the return of gastric motility, while 10% described the return of intestinal motility. High variation in definitions and outcome measures has limited the generalizability of research into postoperative bowel function in children. Without standardization, it will be impossible to compare research results and evaluate treatments. In children, the return of gastric motility seemingly should get more focus compared to adults. Therefore, we believe that a definition of postoperative ileus with an accompanying core outcome set, developed by a multidisciplinary team, specifically for children is required.

Keywords

Abdominal surgery - postoperative ileus - return of bowel function - definitions - outcome measures


Publication History

Received: 27 October 2021

Accepted: 11 February 2022

Article published online:
15 September 2022

© 2022. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

  • References

  • 1 Schattenkerk LDE, Musters GD, Nijssen DJ, de Jonge WJ, de Vries R, van Heurn E. The incidence of different forms of ileus following surgery for abdominal birth defects in infants: a systematic review with a meta-analysis method. Innov Surg Sci 2021; 6 (03) 3-11
    PubMedGoogle Scholar
  • 2 Kulaylat AN, Rocourt DV, Tsai AY. et al. Understanding readmissions in children undergoing surgery: a pediatric NSQIP analysis. J Pediatr Surg 2018; 53 (07) 1280-1287
    CrossrefPubMedGoogle Scholar
  • 3 Vather R, Trivedi S, Bissett I. Defining postoperative ileus: results of a systematic review and global survey. J Gastrointest Surg 2013; 17 (05) 962-972
    CrossrefPubMedGoogle Scholar
  • 4 Gero D, Gié O, Hübner M, Demartines N, Hahnloser D. Postoperative ileus: in search of an international consensus on definition, diagnosis, and treatment. Langenbecks Arch Surg 2017; 402 (01) 149-158
    CrossrefPubMedGoogle Scholar
  • 5 Felder S, Margel D, Murrell Z, Fleshner P. Usefulness of bowel sound auscultation: a prospective evaluation. J Surg Educ 2014; 71 (05) 768-773
    CrossrefPubMedGoogle Scholar
  • 6 Chapman SJ, Thorpe G, Vallance AE, Harji DP, Lee MJ, Fearnhead NS. Association of Coloproctology of Great Britain and Ireland Gastrointestinal Recovery Group. Systematic review of definitions and outcome measures for return of bowel function after gastrointestinal surgery. BJS Open 2018; 3 (01) 1-10
    CrossrefPubMedGoogle Scholar
  • 7 Cook-Sather SD, Litman RS. Modern fasting guidelines in children. Best Pract Res Clin Anaesthesiol 2006; 20 (03) 471-481
    CrossrefPubMedGoogle Scholar
  • 8 Frykholm P, Schindler E, Sümpelmann R, Walker R, Weiss M. Preoperative fasting in children: review of existing guidelines and recent developments. Br J Anaesth 2018; 120 (03) 469-474
    CrossrefPubMedGoogle Scholar
  • 9 Moher D, Liberati A, Tetzlaff J, Altman DG. PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ 2009; 339: b2535
    CrossrefPubMedGoogle Scholar
  • 10 Ouzzani M, Hammady H, Fedorowicz Z, Elmagarmid A. Rayyan—a web and mobile app for systematic reviews. Syst Rev 2016; 5 (01) 210
    CrossrefPubMedGoogle Scholar
  • 11 Abantanga FA. Nasogastric tube use in children after abdominal surgery—how long should it be kept in situ?. West Afr J Med 2012; 31 (01) 19-23
    PubMedGoogle Scholar
  • 12 Alexander F, Difiore J, Stallion A. Triangular tapered duodenoplasty for the treatment of congenital duodenal obstruction. J Pediatr Surg 2002; 37 (06) 862-864
    CrossrefPubMedGoogle Scholar
  • 13 Alshehri A, Emil S, Laberge JM, Skarsgard E. Canadian Pediatric Surgery Network. Outcomes of early versus late intestinal operations in patients with gastroschisis and intestinal atresia: results from a prospective national database. J Pediatr Surg 2013; 48 (10) 2022-2026
    CrossrefPubMedGoogle Scholar
  • 14 Amanollahi O, Azizi B. The comparative study of the outcomes of early and late oral feeding in intestinal anastomosis surgeries in children. Afr J Paediatr Surg 2013; 10 (02) 74-77
    CrossrefPubMedGoogle Scholar
  • 15 Ashjaei B, Ghamari Khameneh A, Darban Hosseini Amirkhiz G, Nazeri N. Early oral feeding versus traditional feeding after transanal endorectal pull-through procedure in Hirschsprung's disease. Medicine (Baltimore) 2019; 98 (10) e14829
    CrossrefPubMedGoogle Scholar
  • 16 Bailez MM, Dibenedetto V, Elmo G, Korman L. Laparoscopic sigmoid vaginal replacement. Pediatr Endosurg Innovative Tech. 2004; 8 (04) 295-301
    CrossrefPubMedGoogle Scholar
  • 17 Bethell GS, Long AM, Knight M, Hall NJ. BAPS-CASS. The impact of trisomy 21 on epidemiology, management, and outcomes of congenital duodenal obstruction: a population-based study. Pediatr Surg Int 2020; 36 (04) 477-483
    CrossrefPubMedGoogle Scholar
  • 18 Blanco-Rodríguez G, Penchyna-Grub J, Porras-Hernández JD, Trujillo-Ponce A. Transluminal endoscopic electrosurgical incision of fenestrated duodenal membranes. Pediatr Surg Int 2008; 24 (06) 711-714
    CrossrefPubMedGoogle Scholar
  • 19 Bolmers MD, van Rossem CC, Gorter RR, Bemelman WA, van Geloven AAW, Heij HA. Snapshot Appendicitis Collaborative Study group. Imaging in pediatric appendicitis is key to a low normal appendix percentage: a national audit on the outcome of appendectomy for appendicitis in children. Pediatr Surg Int 2018; 34 (05) 543-551
    CrossrefPubMedGoogle Scholar
  • 20 Cavuşoğlu YH, Azili MN, Karaman A. et al. Does gum chewing reduce postoperative ileus after intestinal resection in children? A prospective randomized controlled trial. Eur J Pediatr Surg 2009; 19 (03) 171-173
    Article in Thieme ConnectPubMedGoogle Scholar
  • 21 Chen LE, Minkes RK, Langer JC. Laparoscopic versus open surgery for malrotation without volvulus. Pediatr Endosurg Innovative Tech 2003; 7 (04) 433-438
    CrossrefPubMedGoogle Scholar
  • 22 Chittmittrapap S, Kitisin P, Navicharern P. One layer continuous anastomosis of the alimentary tract with absorbable polydioxanone suture. J Med Assoc Thai 1993; 76 (05) 264-270
    PubMedGoogle Scholar
  • 23 Chowdhary SK, Kandpal DK, Agarwal D. et al. Endoscopic esophageal substitution for pure esophageal atresia and wide gap esophageal atresia: a report of five cases with minimum follow-up of twelve months. J Pediatr Surg 2016; 51 (03) 360-363
    CrossrefPubMedGoogle Scholar
  • 24 Curran TJ, Raffensperger JG. Laparoscopic Swenson pull-through: a comparison with the open procedure. J Pediatr Surg 1996; 31 (08) 1155-1156 , discussion 1156–1157
    CrossrefPubMedGoogle Scholar
  • 25 Curry JI, Lander AD, Stringer MDA. BAPS Multicentre Research Committee. A multicenter, randomized, double-blind, placebo-controlled trial of the prokinetic agent erythromycin in the postoperative recovery of infants with gastroschisis. J Pediatr Surg 2004; 39 (04) 565-569
    CrossrefPubMedGoogle Scholar
  • 26 Davila-Perez R, Bracho-Blanchet E, Galindo-Rocha F. et al. Early feeding vs 5-day fasting after distal elective bowel anastomoses in children. A randomized controlled trial. Surg Sci 2013; 04 (01) 4
    CrossrefPubMedGoogle Scholar
  • 27 Davila-Perez R, Bracho-Blanchet E, Tovilla-Mercado JM, Hernandez-Plata JA, Reyes-Lopez A, Nieto-Zermeño J. Unnecessary gastric decompression in distal elective bowel anastomoses in children: a randomized study. World J Surg 2010; 34 (05) 947-953
    CrossrefPubMedGoogle Scholar
  • 28 Deepak J, Agarwal P, Bagdi RK. et al. Laparoscopic appendicectomy is a favorable alternative for complicated appendicitis in children. J Indian Assoc Pediatr Surg 2008; 13 (03) 97-100
    CrossrefPubMedGoogle Scholar
  • 29 Diao M, Li L, Cheng W. Single-incision laparoscopic hepaticojejunostomy for children with perforated choledochal cysts. Surg Endosc 2018; 32 (07) 3402-3409
    CrossrefPubMedGoogle Scholar
  • 30 Diao M, Li L, Cheng W. Single-incision laparoscopic repair for iatrogenic duodenal injury in children with choledochal cysts. J Laparoendosc Adv Surg Tech A 2019; 29 (06) 869-872
    CrossrefPubMedGoogle Scholar
  • 31 Dutta S, Rothenberg SS, Chang J, Bealer J. Total intracorporeal laparoscopic resection of Crohn's disease. J Pediatr Surg 2003; 38 (05) 717-719
    CrossrefPubMedGoogle Scholar
  • 32 Ekingen G, Ceran C, Guvenc BH, Tuzlaci A, Kahraman H. Early enteral feeding in newborn surgical patients. Nutrition 2005; 21 (02) 142-146
    CrossrefPubMedGoogle Scholar
  • 33 El-Deeb A, El-Morsy GZ, Ghanem AAA, Elsharkawy AA, Elmetwally AS. The effects of intravenous lidocaine infusion on hospital stay after major abdominal pediatric surgery. A randomized double-blinded study. Egypt J Anaesth 2013; 29 (03) 225-230
    CrossrefPubMedGoogle Scholar
  • 34 Eltayeb AA, Mostafa MM, Ibrahim NH, Eltayeb AA. The role of surgery in management of necrotizing enterocolitis. Int J Surg 2010; 8 (06) 458-461
    CrossrefPubMedGoogle Scholar
  • 35 Emil S, Gaied F, Lo A. et al. Gangrenous appendicitis in children: a prospective evaluation of definition, bacteriology, histopathology, and outcomes. J Surg Res 2012; 177 (01) 123-126
    CrossrefPubMedGoogle Scholar
  • 36 Greason KL, Allshouse MJ, Thompson WR, Rappold JF, Downey EC. A prospective, randomized evaluation of laparoscopic versus open pyloromyotomy in the treatment of infantile hypertrophic pyloric stenosis. Pediatr Endosurg Innovative Tech 1997; 1 (03) 175-179
    CrossrefPubMedGoogle Scholar
  • 37 Gundeti MS, Acharya SS, Zagaja GP, Shalhav AL. Paediatric robotic-assisted laparoscopic augmentation ileocystoplasty and Mitrofanoff appendicovesicostomy (RALIMA): feasibility of and initial experience with the University of Chicago technique. BJU Int 2011; 107 (06) 962-969
    CrossrefPubMedGoogle Scholar
  • 38 Gunnarsdóttir A, Larsson LT, Arnbjörnsson E. Transanal endorectal vs. Duhamel pull-through for Hirschsprung's disease. Eur J Pediatr Surg 2010; 20 (04) 242-246
    Article in Thieme ConnectPubMedGoogle Scholar
  • 39 Haid B, Karl A, Koen M, Mottl W, Haid A, Oswald J. Enhanced recovery after surgery protocol for pediatric urological augmentation and diversion surgery using small bowel. J Urol 2018; 200 (05) 1100-1106
    CrossrefPubMedGoogle Scholar
  • 40 Hong L, Wu Y, Yan Z, Xu M, Chu J, Chen QM. Laparoscopic surgery for choledochal cyst in children: a case review of 31 patients. Eur J Pediatr Surg 2008; 18 (02) 67-71
    Article in Thieme ConnectPubMedGoogle Scholar
  • 41 Ibrahim MM, Abd El Razik M, Abdelkader AM. Laparoscopic rectopexy: is it useful for persistent rectal prolapse in children?. World J Lap Surg 2014; 7 (02) 92-96
    PubMedGoogle Scholar
  • 42 Jona JZ. The ‘gentle touch’ technique in the treatment of gastroschisis. J Pediatr Surg 2003; 38 (07) 1036-1038
    CrossrefPubMedGoogle Scholar
  • 43 Khan NA, Choudhury SR, Yadav PS, Prakash R, Patel JN. Role of nasogastric tube in children undergoing elective distal bowel surgery. Pediatr Surg Int 2017; 33 (02) 229-234
    CrossrefPubMedGoogle Scholar
  • 44 Kokesova A, Coufal S, Frybova B, Kverka M, Rygl M. The intestinal fatty acid-binding protein as a marker for intestinal damage in gastroschisis. PLoS One 2019; 14 (01) e0210797
    CrossrefPubMedGoogle Scholar
  • 45 Kumar R, Mackay A, Borzi P. Laparoscopic Swenson procedure—an optimal approach for both primary and secondary pull-through for Hirschsprung's disease. J Pediatr Surg 2003; 38 (10) 1440-1443
    CrossrefPubMedGoogle Scholar
  • 46 Lander A, Redkar R, Nicholls G. et al. Cisapride reduces neonatal postoperative ileus: randomised placebo controlled trial. Arch Dis Child Fetal Neonatal Ed 1997; 77 (02) F119-F122
    CrossrefPubMedGoogle Scholar
  • 47 Lejus C, Delile L, Plattner V. et al. Randomized, single-blinded trial of laparoscopic versus open appendectomy in children: effects on postoperative analgesia. Anesthesiology 1996; 84 (04) 801-806
    CrossrefPubMedGoogle Scholar
  • 48 Li AW, Zhang WT, Li FH, Cui XH, Duan XS. A new modification of transanal Soave pull-through procedure for Hirschsprung's disease. Chin Med J (Engl) 2006; 119 (01) 37-42
    CrossrefPubMedGoogle Scholar
  • 49 Little DC, Custer MD, May BH, Blalock SE, Cooney DR. Laparoscopic appendectomy: an unnecessary and expensive procedure in children?. J Pediatr Surg 2002; 37 (03) 310-317
    CrossrefPubMedGoogle Scholar
  • 50 Liu Q, Hao F, Chen B, Li L, Liu Q, Guo C. Multi-center prospective study of restrictive post-operative antibiotic treatment of children with complicated appendicitis. Surg Infect (Larchmt) 2020; 21 (09) 778-783
    CrossrefPubMedGoogle Scholar
  • 51 López-Jaimez G, Cuello-García CA. Use of chewing gum in children undergoing an appendectomy: a randomized clinical controlled trial. Int J Surg 2016; 32: 38-42
    CrossrefPubMedGoogle Scholar
  • 52 Mabula JB, Kayange NM, Manyama M, Chandika AB, Rambau PF, Chalya PL. Hirschsprung's disease in children: a five year experience at a university teaching hospital in northwestern Tanzania. BMC Res Notes 2014; 7: 410
    CrossrefPubMedGoogle Scholar
  • 53 Mamatha B, Alladi A. Early oral feeding in pediatric intestinal anastomosis. Indian J Surg 2015; 77 (Suppl. 02) 670-672
    CrossrefPubMedGoogle Scholar
  • 54 Mandee S, Butmangkun W, Aroonpruksakul N, Tantemsapya N, von Bormann B, Suraseranivongse S. Effects of a restrictive fluid regimen in pediatric patients undergoing major abdominal surgery. Paediatr Anaesth 2015; 25 (05) 530-537
    CrossrefPubMedGoogle Scholar
  • 55 Maroof SA, Khan MJ, Khan Y, Uzair M. Surgical management of omphalomesenteric duct remnants in children. JPMI 2009; 23 (02) 179-183
    PubMedGoogle Scholar
  • 56 Mattioli G, Palomba L, Avanzini S. et al. Fast-track surgery of the colon in children. J Laparoendosc Adv Surg Tech A 2009; 19 (Suppl. 01) S7-S9
    CrossrefPubMedGoogle Scholar
  • 57 Miyano G, Urao M, Lane GJ, Kato Y, Okazaki T, Yamataka A. A prospective analysis of endoloops and endostaples for closing the stump of the appendix in children. J Laparoendosc Adv Surg Tech A 2011; 21 (02) 177-179
    CrossrefPubMedGoogle Scholar
  • 58 Padankatti LR, Pramod RK, Gupta A, Ramachandran P. Laparoscopic versus open appendicectomy for complicated appendicitis: a prospective study. J Indian Assoc Pediatr Surg 2008; 13 (03) 104-106
    CrossrefPubMedGoogle Scholar
  • 59 Razzaq A, Safdar CA, Ali S. Erythromycin establishes early oral feeding in neonates operated for congenital intestinal atresias. Pediatr Surg Int 2009; 25 (04) 361-364
    CrossrefPubMedGoogle Scholar
  • 60 Reismann M, Arar M, Hofmann A, Schukfeh N, Ure B. Feasibility of fast-track elements in pediatric surgery. Eur J Pediatr Surg 2012; 22 (01) 40-44
    Article in Thieme ConnectPubMedGoogle Scholar
  • 61 Reismann M, Dingemann J, Wolters M, Laupichler B, Suempelmann R, Ure BM. Fast-track concepts in routine pediatric surgery: a prospective study in 436 infants and children. Langenbecks Arch Surg 2009; 394 (03) 529-533
    CrossrefPubMedGoogle Scholar
  • 62 Reismann M, von Kampen M, Laupichler B, Suempelmann R, Schmidt AI, Ure BM. Fast-track surgery in infants and children. J Pediatr Surg 2007; 42 (01) 234-238
    CrossrefPubMedGoogle Scholar
  • 63 Rove KO, Brockel MA, Saltzman AF. et al. Prospective study of enhanced recovery after surgery protocol in children undergoing reconstructive operations. J Pediatr Urol 2018; 14 (03) 252.e1-252.e9
    CrossrefPubMedGoogle Scholar
  • 64 Sangkhathat S, Patrapinyokul S, Tadyathikom K. Early enteral feeding after closure of colostomy in pediatric patients. J Pediatr Surg 2003; 38 (10) 1516-1519
    CrossrefPubMedGoogle Scholar
  • 65 Santos-Jasso KA, Lezama-Del Valle P, Arredondo-Garcia JL, García-De la Puente S, Martinez-Garcia MC. Efficacy and safety of an abbreviated perioperative care bundle versus standard perioperative care in children undergoing elective bowel anastomoses: a randomized, noninferiority trial. J Pediatr Surg 2020; 55 (10) 2042-2047
    CrossrefPubMedGoogle Scholar
  • 66 Sato S, Nishijima E, Muraji T, Tsugawa C, Kimura K. Jejunoileal atresia: a 27-year experience. J Pediatr Surg 1998; 33 (11) 1633-1635
    CrossrefPubMedGoogle Scholar
  • 67 Seqsaqa M, Rozeik AE, Khalifa M, Ashri HNA. Laparoscopic versus open appendectomy in complicated appendicitis in children: a single center study. Egypt Pediatr Assoc Gaz 2020; 68 (01) 20-25
    PubMedGoogle Scholar
  • 68 Shakya VC, Agrawal CS, Adhikary S. Initial experience with Soave's transabdominal pull-through: an observational study. Int J Surg 2010; 8 (03) 225-228
    CrossrefPubMedGoogle Scholar
  • 69 Sholadoye TT, Suleiman AF, Mshelbwala PM, Ameh EA. Early oral feeding following intestinal anastomoses in children is safe. Afr J Paediatr Surg 2012; 9 (02) 113-116
    CrossrefPubMedGoogle Scholar
  • 70 Shores DR, Alaish SM, Aucott SW. et al. Postoperative enteral nutrition guidelines reduce the risk of intestinal failure-associated liver disease in surgical infants. J Pediatr 2018; 195: 140-147.e1
    CrossrefPubMedGoogle Scholar
  • 71 Shrestha MK, Sherchan M, Dhaubhadel BK, Basnet RB. Early experience with single-stage transanal endorectal pull through for rectosigmoid Hirschsprung's disease. J Nepal Paediatr Soc 2014; 34 (03) 188-194
    CrossrefPubMedGoogle Scholar
  • 72 Somri M, Matter I, Parisinos CA. et al. The effect of combined spinal-epidural anesthesia versus general anesthesia on the recovery time of intestinal function in young infants undergoing intestinal surgery: a randomized, prospective, controlled trial. J Clin Anesth 2012; 24 (06) 439-445
    CrossrefPubMedGoogle Scholar
  • 73 St Peter SD, Adibe OO, Juang D. et al. Single incision versus standard 3-port laparoscopic appendectomy: a prospective randomized trial. Ann Surg 2011; 254 (04) 586-590
    CrossrefPubMedGoogle Scholar
  • 74 Tannuri ACA, Silva LM, Leal AJG, Moraes AC, Tannuri U. Does administering albumin to postoperative gastroschisis patients improve outcome?. Clinics (São Paulo) 2012; 67 (02) 107-111
    CrossrefPubMedGoogle Scholar
  • 75 Tian X, Yang P, Su T. et al. Intraperitoneal ropivacaine and early postoperative pain and postsurgical outcomes after laparoscopic herniorrhaphy in toddlers: a randomized clinical trial. Paediatr Anaesth 2016; 26 (09) 891-898
    CrossrefPubMedGoogle Scholar
  • 76 Walter-Nicolet E, Rousseau V, Kieffer F. et al. Neonatal outcome of gastroschisis is mainly influenced by nutritional management. J Pediatr Gastroenterol Nutr 2009; 48 (05) 612-617
    CrossrefPubMedGoogle Scholar
  • 77 Wiernicka A, Matuszczyk M, Szlagatys-Sidorkiewicz A. et al. Tolerability and safety of early enteral nutrition in children after percutaneous endoscopic gastrostomy placement: a multicentre randomised controlled trial. Clin Nutr 2019; 38 (04) 1544-1548
    CrossrefPubMedGoogle Scholar
  • 78 Xiao H, Huang R, Chen L, Diao M, Li L. The application of a shorter loop in Kasai portoenterostomy reconstruction for Ohi Type III biliary atresia: a prospective randomized controlled trial. J Surg Res 2018; 232: 492-496
    CrossrefPubMedGoogle Scholar
  • 79 Yadav PS, Choudhury SR, Grover JK, Gupta A, Chadha R, Sigalet DL. Early feeding in pediatric patients following stoma closure in a resource limited environment. J Pediatr Surg 2013; 48 (05) 977-982
    CrossrefPubMedGoogle Scholar
  • 80 Yehya A, Gamaan I, Abdelrazek M, Shahin M, Seddek A, Abdelhafez M. Laparoscopic suture versus mesh rectopexy for the treatment of persistent complete rectal prolapse in children: a comparative randomized study. Minim Invasive Surg 2020; 2020: 3057528
    PubMedGoogle Scholar
  • 81 Zhang Q, Zhao P. Influence of gum chewing on return of gastrointestinal function after gastric abdominal surgery in children. Eur J Pediatr Surg 2008; 18 (01) 44-46
    Article in Thieme ConnectPubMedGoogle Scholar
  • 82 Chusilp S, Yamoto M, Vejchapipat P, Ganji N, Pierro A. Nasogastric decompression after intestinal surgery in children: a systematic review and meta-analysis. Pediatr Surg Int 2021; 37 (03) 377-388
    CrossrefPubMedGoogle Scholar
  • 83 van Bree SH, Bemelman WA, Hollmann MW. et al. Identification of clinical outcome measures for recovery of gastrointestinal motility in postoperative ileus. Ann Surg 2014; 259 (04) 708-714
    CrossrefPubMedGoogle Scholar