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Drug Res (Stuttg) 2017; 67(02): 70-76
DOI: 10.1055/s-0042-113383
Review
© Georg Thieme Verlag KG Stuttgart · New York

A Review on Potential Role of Silver Nanoparticles and Possible Mechanisms of their Actions on Bacteria

Bahar Khalandi
2   Department of Medical Nanotechnology, Faculty of Advanced Medical Science, Medical, University of Tabriz, Tabriz, Iran
3   Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
5   Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
,
Nahideh Asadi
2   Department of Medical Nanotechnology, Faculty of Advanced Medical Science, Medical, University of Tabriz, Tabriz, Iran
4   Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
5   Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
,
Morteza Milani
2   Department of Medical Nanotechnology, Faculty of Advanced Medical Science, Medical, University of Tabriz, Tabriz, Iran
,
Soodabeh Davaran
4   Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
2   Department of Medical Nanotechnology, Faculty of Advanced Medical Science, Medical, University of Tabriz, Tabriz, Iran
,
Azam Jafari Najaf Abadi
5   Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
,
Elham Abasi
4   Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
2   Department of Medical Nanotechnology, Faculty of Advanced Medical Science, Medical, University of Tabriz, Tabriz, Iran
,
Abolfazl Akbarzadeh
1   Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
2   Department of Medical Nanotechnology, Faculty of Advanced Medical Science, Medical, University of Tabriz, Tabriz, Iran
3   Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
› Author Affiliations
Further Information

Publication History

received 19 June 2016

accepted 18 July 2016

Publication Date:
07 November 2016 (online)

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Abstract

The antimicrobial property of silver is associated to the quantity of silver and the grade of silver released. The ionized silver is extremely sensitive, as it binds to tissue proteins and gets operational alterations in the bacterial cell wall and nuclear membrane leading to cell modification and death.Silver nanoparticles have the talent to anchor to the bacterial cell wall and consequently infiltrate it, so causing physical modifications in the cell membrane like the absorptivity of the cell membrane and death of the cell. There are numerous concepts on the act of silver nanoparticle on bacteria to reason the microbicidal influence.

Key words

antimicrobial property - silver nanoparticle - nuclear membrane - bacterial cell
 

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