Clin Colon Rectal Surg 2022; 35(03): 244-260
DOI: 10.1055/s-0041-1740045
Review Article

Colorectal Surgery in Critically Unwell Patients: A Multidisciplinary Approach

1   Department of Intensive Care Medicine, Peninsula Health, Frankston, Victoria, Australia
2   Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia
3   Department of Intensive Care, The Bays Healthcare, Mornington, Victoria, Australia
,
Robert Wengritzky
4   Department of Anaesthesia, Peninsula Health, Frankston, Victoria, Australia
,
Stewart Skinner
5   Department of Surgery, Peninsula Health, Frankston, Victoria, Australia
,
Kiran Shekar
6   Adult Intensive Care Services, the Prince Charles Hospital, Brisbane, Queensland, Australia
7   Queensland University of Technology, University of Queensland, Brisbane, Queensland, Australia
› Author Affiliations
Funding None.

Abstract

A proportion of patients require critical care support following elective or urgent colorectal procedures. Similarly, critically ill patients in intensive care units may also need colorectal surgery on occasions. This patient population is increasing in some jurisdictions given an aging population and increasing societal expectations. As such, this population often includes elderly, frail patients or patients with significant comorbidities. Careful stratification of operative risks including the need for prolonged intensive care support should be part of the consenting process. In high-risk patients, especially in setting of unplanned surgery, treatment goals should be clearly defined, and appropriate ceiling of care should be established to minimize care that is not in the best interest of the patient. In this article we describe approaches to critically unwell patients requiring colorectal surgery and how a multidisciplinary approach with proactive intensive care involvement can help achieve the best outcomes for these patients.



Publication History

Article published online:
09 February 2022

© 2022. Thieme. All rights reserved.

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  • References

  • 1 McGee S, Abernethy III WB, Simel DL. The rational clinical examination. Is this patient hypovolemic?. JAMA 1999; 281 (11) 1022-1029
  • 2 Sevransky J. Clinical assessment of hemodynamically unstable patients. Curr Opin Crit Care 2009; 15 (03) 234-238
  • 3 Varpula M, Tallgren M, Saukkonen K, Voipio-Pulkki LM, Pettilä V. Hemodynamic variables related to outcome in septic shock. Intensive Care Med 2005; 31 (08) 1066-1071
  • 4 Dellinger RP, Levy MM, Carlet JM. et al; International Surviving Sepsis Campaign Guidelines Committee, American Association of Critical-Care Nurses, American College of Chest Physicians, American College of Emergency Physicians, Canadian Critical Care Society, European Society of Clinical Microbiology and Infectious Diseases, European Society of Intensive Care Medicine, European Respiratory Society, International Sepsis Forum, Japanese Association for Acute Medicine, Japanese Society of Intensive Care Medicine, Society of Critical Care Medicine, Society of Hospital Medicine, Surgical Infection Society, World Federation of Societies of Intensive and Critical Care Medicine. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med 2008; 36 (01) 296-327
  • 5 Lima A, Jansen TC, van Bommel J, Ince C, Bakker J. The prognostic value of the subjective assessment of peripheral perfusion in critically ill patients. Crit Care Med 2009; 37 (03) 934-938
  • 6 Sandler G. The importance of the history in the medical clinic and the cost of unnecessary tests. Am Heart J 1980; 100 (6 Pt 1): 928-931
  • 7 Marik PE, Baram M, Vahid B. Does central venous pressure predict fluid responsiveness? A systematic review of the literature and the tale of seven mares. Chest 2008; 134 (01) 172-178
  • 8 Rivers E, Nguyen B, Havstad S. et al; Early Goal-Directed Therapy Collaborative Group. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001; 345 (19) 1368-1377
  • 9 Dellinger RP, Carlet JM, Masur H. et al; Surviving Sepsis Campaign Management Guidelines Committee. Surviving sepsis campaign guidelines for management of severe sepsis and septic shock. Crit Care Med 2004; 32 (03) 858-873
  • 10 Michard F, Teboul JL. Predicting fluid responsiveness in ICU patients: a critical analysis of the evidence. Chest 2002; 121 (06) 2000-2008
  • 11 Michard F, Lopes MR, Auler Jr JO. Pulse pressure variation: beyond the fluid management of patients with shock. Crit Care 2007; 11 (03) 131
  • 12 Michard F, Boussat S, Chemla D. et al. Relation between respiratory changes in arterial pulse pressure and fluid responsiveness in septic patients with acute circulatory failure. Am J Respir Crit Care Med 2000; 162 (01) 134-138
  • 13 Marik PE, Cavallazzi R, Vasu T, Hirani A. Dynamic changes in arterial waveform derived variables and fluid responsiveness in mechanically ventilated patients: a systematic review of the literature. Crit Care Med 2009; 37 (09) 2642-2647
  • 14 Biais M, Nouette-Gaulain K, Cottenceau V, Revel P, Sztark F. Uncalibrated pulse contour-derived stroke volume variation predicts fluid responsiveness in mechanically ventilated patients undergoing liver transplantation. Br J Anaesth 2008; 101 (06) 761-768
  • 15 Pinsky MR. Functional haemodynamic monitoring. Curr Opin Crit Care 2014; 20 (03) 288-293
  • 16 Marik PE, Monnet X, Teboul JL. Hemodynamic parameters to guide fluid therapy. Ann Intensive Care 2011; 1 (01) 1
  • 17 Rudski LG, Lai WW, Afilalo J. et al. Guidelines for the echocardiographic assessment of the right heart in adults: a report from the American Society of Echocardiography endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology, and the Canadian Society of Echocardiography. J Am Soc Echocardiogr 2010; 23 (07) 685-713 , quiz 786–788
  • 18 van Beest P, Wietasch G, Scheeren T, Spronk P, Kuiper M. Clinical review: use of venous oxygen saturations as a goal—a yet unfinished puzzle. Crit Care 2011; 15 (05) 232
  • 19 Nebout S, Pirracchio R. Should we monitor ScVO(2) in critically ill patients?. Cardiol Res Pract 2012; 2012: 370697
  • 20 Marik PE, Baram M. Noninvasive hemodynamic monitoring in the intensive care unit. Crit Care Clin 2007; 23 (03) 383-400
  • 21 Marik PE. Noninvasive cardiac output monitors: a state-of the-art review. J Cardiothorac Vasc Anesth 2013; 27 (01) 121-134
  • 22 De Backer D, Marx G, Tan A. et al. Arterial pressure-based cardiac output monitoring: a multicenter validation of the third-generation software in septic patients. Intensive Care Med 2011; 37 (02) 233-240
  • 23 Noritomi DT, Vieira ML, Mohovic T. et al. Echocardiography for hemodynamic evaluation in the intensive care unit. Shock 2010; 34 (Suppl. 01) 59-62
  • 24 De Backer D. Ultrasonic evaluation of the heart. Curr Opin Crit Care 2014; 20 (03) 309-314
  • 25 Creteur J, Carollo T, Soldati G, Buchele G, De Backer D, Vincent JL. The prognostic value of muscle StO2 in septic patients. Intensive Care Med 2007; 33 (09) 1549-1556
  • 26 Masip J, Mesquida J, Luengo C. et al. Near-infrared spectroscopy StO2 monitoring to assess the therapeutic effect of drotrecogin alfa (activated) on microcirculation in patients with severe sepsis or septic shock. Ann Intensive Care 2013; 3 (01) 30
  • 27 Gómez H, Torres A, Polanco P. et al. Use of non-invasive NIRS during a vascular occlusion test to assess dynamic tissue O(2) saturation response. Intensive Care Med 2008; 34 (09) 1600-1607
  • 28 Girard TD, Kress JP, Fuchs BD. et al. Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): a randomised controlled trial. Lancet 2008; 371 (9607): 126-134
  • 29 Sessler CN, Gosnell MS, Grap MJ. et al. The Richmond Agitation-Sedation scale: validity and reliability in adult intensive care unit patients. Am J Respir Crit Care Med 2002; 166 (10) 1338-1344
  • 30 Wong-Baker FACES® Pain Rating Scale. 2015 . Accessed February 3rd, 2021). Available at: http://www.WongBakerFACES.org
  • 31 Barr J, Fraser GL, Puntillo K. et al; American College of Critical Care Medicine. Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit. Crit Care Med 2013; 41 (01) 263-306
  • 32 Ely EW, Margolin R, Francis J. et al. Evaluation of delirium in critically ill patients: validation of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU). Crit Care Med 2001; 29 (07) 1370-1379
  • 33 Tang B, Green C, Yeoh AC, Husain F, Subramaniam A. Post-operative outcomes in older patients: a single-centre observational study. ANZ J Surg 2018; 88 (05) 421-427
  • 34 Semler MW, Self WH, Rice TW. Balanced crystalloids versus saline in critically Ill adults. N Engl J Med 2018; 378 (20) 1951
  • 35 Meng L, Yu W, Wang T, Zhang L, Heerdt PM, Gelb AW. Blood pressure targets in perioperative care. Hypertension 2018; 72 (04) 806-817
  • 36 Retter A, Wyncoll D, Pearse R. et al; British Committee for Standards in Haematology. Guidelines on the management of anaemia and red cell transfusion in adult critically ill patients. Br J Haematol 2013; 160 (04) 445-464
  • 37 Muñoz M, Acheson AG, Auerbach M. et al. International consensus statement on the peri-operative management of anaemia and iron deficiency. Anaesthesia 2017; 72 (02) 233-247
  • 38 Poulton T, Murray D. National Emergency Laparotomy Audit (NELA) project team. Pre-optimisation of patients undergoing emergency laparotomy: a review of best practice. Anaesthesia 2019; 74 (Suppl. 01) 100-107
  • 39 James S, Jhanji S, Smith A, O'Brien G, Fitzgibbon M, Pearse RM. Comparison of the prognostic accuracy of scoring systems, cardiopulmonary exercise testing, and plasma biomarkers: a single-centre observational pilot study. Br J Anaesth 2014; 112 (03) 491-497
  • 40 Dillon ST, Vasunilashorn SM, Ngo L. et al. Higher C-reactive protein levels predict postoperative delirium in older patients undergoing major elective surgery: a longitudinal nested case-control study. Biol Psychiatry 2017; 81 (02) 145-153
  • 41 Wolters U, Wolf T, Stützer H, Schröder T. ASA classification and perioperative variables as predictors of postoperative outcome. Br J Anaesth 1996; 77 (02) 217-222
  • 42 Sankar A, Johnson SR, Beattie WS, Tait G, Wijeysundera DN. Reliability of the American Society of Anesthesiologists physical status scale in clinical practice. Br J Anaesth 2014; 113 (03) 424-432
  • 43 Peden C, Scott MJ. Anesthesia for emergency abdominal surgery. Anesthesiol Clin 2015; 33 (01) 209-221
  • 44 Levy MM, Artigas A, Phillips GS. et al. Outcomes of the surviving sepsis campaign in intensive care units in the USA and Europe: a prospective cohort study. Lancet Infect Dis 2012; 12 (12) 919-924
  • 45 Neuman MD, Silber JH, Elkassabany NM, Ludwig JM, Fleisher LA. Comparative effectiveness of regional versus general anesthesia for hip fracture surgery in adults. Anesthesiology 2012; 117 (01) 72-92
  • 46 Rigg JR, Jamrozik K, Myles PS. et al; MASTER Anaethesia Trial Study Group. Epidural anaesthesia and analgesia and outcome of major surgery: a randomised trial. Lancet 2002; 359 (9314): 1276-1282
  • 47 van Lier F, van der Geest PJ, Hoeks SE. et al. Epidural analgesia is associated with improved health outcomes of surgical patients with chronic obstructive pulmonary disease. Anesthesiology 2011; 115 (02) 315-321
  • 48 Baldini G, Fawcett WJ. Anesthesia for colorectal surgery. Anesthesiol Clin 2015; 33 (01) 93-123
  • 49 Working P. Association of Anaesthetists of Great B, Ireland, Obstetric Anaesthetists A, Regional Anaesthesia UK. Regional anaesthesia and patients with abnormalities of coagulation: the Association of Anaesthetists of Great Britain & Ireland The Obstetric Anaesthetists' Association Regional Anaesthesia UK. Anaesthesia 2013; 68: 966-972
  • 50 Lai HC, Chan SM, Lu CH, Wong CS, Cherng CH, Wu ZF. Planning for operating room efficiency and faster anesthesia wake-up time in open major upper abdominal surgery. Medicine (Baltimore) 2017; 96 (07) e6148
  • 51 Dunn LK, Durieux ME. Perioperative use of intravenous lidocaine. Anesthesiology 2017; 126 (04) 729-737
  • 52 Nelson H, Sargent DJ, Wieand HS. et al; Clinical Outcomes of Surgical Therapy Study Group. A comparison of laparoscopically assisted and open colectomy for colon cancer. N Engl J Med 2004; 350 (20) 2050-2059
  • 53 Buunen M, Veldkamp R, Hop WC. et al; Colon Cancer Laparoscopic or Open Resection Study Group. Survival after laparoscopic surgery versus open surgery for colon cancer: long-term outcome of a randomised clinical trial. Lancet Oncol 2009; 10 (01) 44-52
  • 54 Lacy AM, García-Valdecasas JC, Delgado S. et al. Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial. Lancet 2002; 359 (9325): 2224-2229
  • 55 Kennedy RH, Francis EA, Wharton R. et al. Multicenter randomized controlled trial of conventional versus laparoscopic surgery for colorectal cancer within an enhanced recovery programme: EnROL. J Clin Oncol 2014; 32 (17) 1804-1811
  • 56 Bonjer HJ, Hop WC, Nelson H. et al; Transatlantic Laparoscopically Assisted vs Open Colectomy Trials Study Group. Laparoscopically assisted vs open colectomy for colon cancer: a meta-analysis. Arch Surg 2007; 142 (03) 298-303
  • 57 Jackson TD, Kaplan GG, Arena G, Page JH, Rogers Jr SO. Laparoscopic versus open resection for colorectal cancer: a metaanalysis of oncologic outcomes. J Am Coll Surg 2007; 204 (03) 439-446
  • 58 Choi S, Yang SY, Choi GJ, Kim BG, Kang H. Comparison of pressure- and volume-controlled ventilation during laparoscopic colectomy in patients with colorectal cancer. Sci Rep 2019; 9 (01) 17007
  • 59 Sharma KC, Brandstetter RD, Brensilver JM, Jung LD. Cardiopulmonary physiology and pathophysiology as a consequence of laparoscopic surgery. Chest 1996; 110 (03) 810-815
  • 60 Rauh R, Hemmerling TM, Rist M, Jacobi KE. Influence of pneumoperitoneum and patient positioning on respiratory system compliance. J Clin Anesth 2001; 13 (05) 361-365
  • 61 Grabowski JE, Talamini MA. Physiological effects of pneumoperitoneum. J Gastrointest Surg 2009; 13 (05) 1009-1016
  • 62 Hardacre JM, Talamini MA. Pulmonary and hemodynamic changes during laparoscopy—are they important?. Surgery 2000; 127 (03) 241-244
  • 63 Choi SB, Park HK, Hong JH, Kim BG, Kang H. Postoperative respiratory complications and peak airway pressure during laparoscopic colectomy in patients with colorectal cancer. Surg Laparosc Endosc Percutan Tech 2015; 25 (01) 83-88
  • 64 Futier E, Constantin JM, Paugam-Burtz C. et al; IMPROVE Study Group. A trial of intraoperative low-tidal-volume ventilation in abdominal surgery. N Engl J Med 2013; 369 (05) 428-437
  • 65 Lam SM, Lau AC, Chan KK. Intraoperative low-tidal-volume ventilation. N Engl J Med 2013; 369 (19) 1861-1862
  • 66 Futier E, Jaber S. Lung-protective ventilation in abdominal surgery. Curr Opin Crit Care 2014; 20 (04) 426-430
  • 67 Futier E, Godet T, Millot A, Constantin JM, Jaber S. Mechanical ventilation in abdominal surgery. Ann Fr Anesth Reanim 2014; 33 (7-8): 472-475
  • 68 Wakeling HG, McFall MR, Jenkins CS. et al. Intraoperative oesophageal Doppler guided fluid management shortens postoperative hospital stay after major bowel surgery. Br J Anaesth 2005; 95 (05) 634-642
  • 69 Brandstrup B. Fluid therapy for the surgical patient. Best Pract Res Clin Anaesthesiol 2006; 20 (02) 265-283
  • 70 Myles PS, Bellomo R, Corcoran T. et al; Australian and New Zealand College of Anaesthetists Clinical Trials Network and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Restrictive versus liberal fluid therapy for major abdominal surgery. N Engl J Med 2018; 378 (24) 2263-2274
  • 71 Miller TE, Pearse RM. Perioperative fluid management: moving toward more answers than questions-a commentary on the RELIEF study. Perioper Med (Lond) 2019; 8: 2
  • 72 Kurz A, Sessler DI, Lenhardt R. Study of Wound Infection and Temperature Group. Perioperative normothermia to reduce the incidence of surgical-wound infection and shorten hospitalization. N Engl J Med 1996; 334 (19) 1209-1215
  • 73 Lenhardt R, Marker E, Goll V. et al. Mild intraoperative hypothermia prolongs postanesthetic recovery. Anesthesiology 1997; 87 (06) 1318-1323
  • 74 Kurz A, Sessler DI, Narzt E, Lenhardt R, Lackner F. Morphometric influences on intraoperative core temperature changes. Anesth Analg 1995; 80 (03) 562-567
  • 75 Rajagopalan S, Mascha E, Na J, Sessler DI. The effects of mild perioperative hypothermia on blood loss and transfusion requirement. Anesthesiology 2008; 108 (01) 71-77
  • 76 Valeri CR, Khabbaz K, Khuri SF. et al. Effect of skin temperature on platelet function in patients undergoing extracorporeal bypass. J Thorac Cardiovasc Surg 1992; 104 (01) 108-116
  • 77 Wolberg AS, Meng ZH, Monroe III DM, Hoffman M. A systematic evaluation of the effect of temperature on coagulation enzyme activity and platelet function. J Trauma 2004; 56 (06) 1221-1228
  • 78 Cirocco WC, Golub RW. Endoscopic treatment of postoperative hemorrhage from a stapled colorectal anastomosis. Am Surg 1995; 61 (05) 460-463
  • 79 Malik AH, East JE, Buchanan GN, Kennedy RH. Endoscopic haemostasis of staple-line haemorrhage following colorectal resection. Colorectal Dis 2008; 10 (06) 616-618
  • 80 Martínez-Serrano MA, Parés D, Pera M. et al. Management of lower gastrointestinal bleeding after colorectal resection and stapled anastomosis. Tech Coloproctol 2009; 13 (01) 49-53
  • 81 Borgman MA, Spinella PC, Perkins JG. et al. The ratio of blood products transfused affects mortality in patients receiving massive transfusions at a combat support hospital. J Trauma 2007; 63 (04) 805-813
  • 82 Srivastava A, Kelleher A. Point-of-care coagulation testing. Contin Educ Anaesth Crit Care Pain 2012; 13: 12-16
  • 83 Nair AS, Naik VM, Rayani BK. FAST HUGS BID: modified mnemonic for surgical patient. Indian J Crit Care Med 2017; 21 (10) 713-714
  • 84 van der Leeden M, Huijsmans R, Geleijn E. et al. Early enforced mobilisation following surgery for gastrointestinal cancer: feasibility and outcomes. Physiotherapy 2016; 102 (01) 103-110
  • 85 Schaller SJ, Anstey M, Blobner M. et al; International Early SOMS-guided Mobilization Research Initiative. Early, goal-directed mobilisation in the surgical intensive care unit: a randomised controlled trial. Lancet 2016; 388 (10052): 1377-1388
  • 86 Lipshutz AK, Gropper MA. Acquired neuromuscular weakness and early mobilization in the intensive care unit. Anesthesiology 2013; 118 (01) 202-215
  • 87 Bartlett MA, Mauck KF, Stephenson CR, Ganesh R, Daniels PR. Perioperative venous thromboembolism prophylaxis. Mayo Clin Proc 2020; 95 (12) 2775-2798
  • 88 Thompson RE, Broussard EK, Flum DR, Wisse BE. Perioperative glycemic control during colorectal surgery. Curr Diab Rep 2016; 16 (03) 32
  • 89 Vincent JL. Give your patient a fast hug (at least) once a day. Crit Care Med 2005; 33 (06) 1225-1229
  • 90 Vincent III WR, Hatton KW. Critically ill patients need “FAST HUGS BID” (an updated mnemonic). Crit Care Med 2009; 37 (07) 2326-2327 , author reply 2327
  • 91 Papadimos TJ, Hensley SJ, Duggan JM. et al. Implementation of the “FASTHUG” concept decreases the incidence of ventilator-associated pneumonia in a surgical intensive care unit. Patient Saf Surg 2008; 2: 3
  • 92 Weibel S, Jelting Y, Pace NL. et al. Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery in adults. Cochrane Database Syst Rev 2018; 6: CD009642
  • 93 Abdallah FW, Chan VW, Brull R. Transversus abdominis plane block: a systematic review. Reg Anesth Pain Med 2012; 37 (02) 193-209
  • 94 Johns N, O'Neill S, Ventham NT, Barron F, Brady RR, Daniel T. Clinical effectiveness of transversus abdominis plane (TAP) block in abdominal surgery: a systematic review and meta-analysis. Colorectal Dis 2012; 14 (10) e635-e642
  • 95 Lumb A, Biercamp C. Chronic obstructive pulmonary disease and anaesthesia. Contin Educ Anaesth Crit Care Pain 2014; 14: 1-5
  • 96 Kayilioglu SI, Dinc T, Sozen I, Bostanoglu A, Cete M, Coskun F. Postoperative fluid management. World J Crit Care Med 2015; 4 (03) 192-201
  • 97 Lobo DN, Bostock KA, Neal KR, Perkins AC, Rowlands BJ, Allison SP. Effect of salt and water balance on recovery of gastrointestinal function after elective colonic resection: a randomised controlled trial. Lancet 2002; 359 (9320): 1812-1818
  • 98 Ruscic KJ, Grabitz SD, Rudolph MI, Eikermann M. Prevention of respiratory complications of the surgical patient: actionable plan for continued process improvement. Curr Opin Anaesthesiol 2017; 30 (03) 399-408
  • 99 Scheeren TW, Wiesenack C, Gerlach H, Marx G. Goal-directed intraoperative fluid therapy guided by stroke volume and its variation in high-risk surgical patients: a prospective randomized multicentre study. J Clin Monit Comput 2013; 27 (03) 225-233
  • 100 Myburgh JA, Higgins A, Jovanovska A, Lipman J, Ramakrishnan N, Santamaria J. CAT Study investigators. A comparison of epinephrine and norepinephrine in critically ill patients. Intensive Care Med 2008; 34 (12) 2226-2234
  • 101 Annane D, Vignon P, Renault A. et al; CATS Study Group. Norepinephrine plus dobutamine versus epinephrine alone for management of septic shock: a randomised trial. Lancet 2007; 370 (9588): 676-684
  • 102 De Backer D, Biston P, Devriendt J. et al; SOAP II Investigators. Comparison of dopamine and norepinephrine in the treatment of shock. N Engl J Med 2010; 362 (09) 779-789
  • 103 Venkatesh B, Finfer S, Cohen J. et al; ADRENAL Trial Investigators and the Australian–New Zealand Intensive Care Society Clinical Trials Group. Adjunctive glucocorticoid therapy in patients with septic shock. N Engl J Med 2018; 378 (09) 797-808
  • 104 Adanir T, Nazli O, Kara C. et al. The relationship between vasopressor dose and anastomotic leak in colon surgery: an experimental trial. Int J Surg 2010; 8 (03) 221-224
  • 105 Zakrison T, Nascimento Jr BA, Tremblay LN, Kiss A, Rizoli SB. Perioperative vasopressors are associated with an increased risk of gastrointestinal anastomotic leakage. World J Surg 2007; 31 (08) 1627-1634
  • 106 Deng C, Bellomo R, Myles P. Systematic review and meta-analysis of the perioperative use of vasoactive drugs on postoperative outcomes after major abdominal surgery. Br J Anaesth 2020; 124 (05) 513-524
  • 107 Allegranzi B, Bischoff P, de Jonge S. et al; WHO Guidelines Development Group. New WHO recommendations on preoperative measures for surgical site infection prevention: an evidence-based global perspective. Lancet Infect Dis 2016; 16 (12) e276-e287
  • 108 Bratzler DW, Dellinger EP, Olsen KM. et al; American Society of Health-System Pharmacists (ASHP), Infectious Diseases Society of America (IDSA), Surgical Infection Society (SIS), Society for Healthcare Epidemiology of America (SHEA). Clinical practice guidelines for antimicrobial prophylaxis in surgery. Surg Infect (Larchmt) 2013; 14 (01) 73-156
  • 109 Nelson RL, Gladman E, Barbateskovic M. Antimicrobial prophylaxis for colorectal surgery. Cochrane Database Syst Rev 2014; (05) CD001181
  • 110 Solomkin JS, Mazuski JE, Bradley JS. et al. Diagnosis and management of complicated intra-abdominal infection in adults and children: guidelines by the Surgical Infection Society and the Infectious Diseases Society of America. Surg Infect (Larchmt) 2010; 11 (01) 79-109
  • 111 Grant SB, Modi PK, Singer EA. Futility and the care of surgical patients: ethical dilemmas. World J Surg 2014; 38 (07) 1631-1637
  • 112 Rawal G, Yadav S, Kumar R. Post-intensive care syndrome: an overview. J Transl Int Med 2017; 5 (02) 90-92
  • 113 Celli BR, Cote CG, Marin JM. et al. The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease. N Engl J Med 2004; 350 (10) 1005-1012
  • 114 Menezes AM, Wehrmeister FC, Perez-Padilla R. et al. The PLATINO study: description of the distribution, stability, and mortality according to the Global Initiative for Chronic Obstructive Lung Disease classification from 2007 to 2017. Int J Chron Obstruct Pulmon Dis 2017; 12: 1491-1501
  • 115 Hlatky MA, Boineau RE, Higginbotham MB. et al. A brief self-administered questionnaire to determine functional capacity (the Duke Activity Status Index). Am J Cardiol 1989; 64 (10) 651-654
  • 116 Coutinho-Myrrha MA, Dias RC, Fernandes AA. et al. Duke Activity Status Index for cardiovascular diseases: validation of the Portuguese translation. Arq Bras Cardiol 2014; 102 (04) 383-390
  • 117 Forrest P. Anaesthesia and right ventricular failure. Anaesth Intensive Care 2009; 37 (03) 370-385
  • 118 McGlothlin D, Ivascu N, Heerdt PM. Anesthesia and pulmonary hypertension. Prog Cardiovasc Dis 2012; 55 (02) 199-217
  • 119 Cuker A, Burnett A, Triller D. et al. Reversal of direct oral anticoagulants: guidance from the anticoagulation forum. Am J Hematol 2019; 94 (06) 697-709
  • 120 Carson JL, Stanworth SJ, Alexander JH. et al. Clinical trials evaluating red blood cell transfusion thresholds: an updated systematic review and with additional focus on patients with cardiovascular disease. Am Heart J 2018; 200: 96-101
  • 121 Seltman AK. Surgical management of Clostridium difficile colitis. Clin Colon Rectal Surg 2012; 25 (04) 204-209
  • 122 Juo YY, Sanaiha Y, Jabaji Z, Benharash P. Trends in diverting loop ileostomy vs total abdominal colectomy as surgical management for Clostridium difficile colitis. JAMA Surg 2019; 154 (10) 899-906
  • 123 Cheng KP, Roslani AC, Sehha N. et al. ALEXIS O-Ring wound retractor vs conventional wound protection for the prevention of surgical site infections in colorectal resections(1). Colorectal Dis 2012; 14 (06) e346-e351
  • 124 Odutayo A, Desborough MJ, Trivella M. et al. Restrictive versus liberal blood transfusion for gastrointestinal bleeding: a systematic review and meta-analysis of randomised controlled trials. Lancet Gastroenterol Hepatol 2017; 2 (05) 354-360
  • 125 Villanueva C, Colomo A, Bosch A. et al. Transfusion strategies for acute upper gastrointestinal bleeding. N Engl J Med 2013; 368 (01) 11-21
  • 126 Arezzo A. Malignant colonic obstruction: to stent or not to stent?. Cir Esp 2017; 95 (03) 121-122
  • 127 Arezzo A, Passera R, Lo Secco G. et al. Stent as bridge to surgery for left-sided malignant colonic obstruction reduces adverse events and stoma rate compared with emergency surgery: results of a systematic review and meta-analysis of randomized controlled trials. Gastrointest Endosc 2017; 86 (03) 416-426
  • 128 Hajizadeh N, Goldfeld K, Crothers K. What happens to patients with COPD with long-term oxygen treatment who receive mechanical ventilation for COPD exacerbation? A 1-year retrospective follow-up study. Thorax 2015; 70 (03) 294-296
  • 129 Caprini JA. Thrombosis risk assessment as a guide to quality patient care. Dis Mon 2005; 51 (2-3): 70-78
  • 130 Bahl V, Hu HM, Henke PK, Wakefield TW, Campbell Jr DA, Caprini JA. A validation study of a retrospective venous thromboembolism risk scoring method. Ann Surg 2010; 251 (02) 344-350
  • 131 Venclauskas L, Maleckas A, Arcelus JI, Force EVGT. ESA VTE Guidelines Task Force. European guidelines on perioperative venous thromboembolism prophylaxis: Surgery in the obese patient. Eur J Anaesthesiol 2018; 35 (02) 147-153
  • 132 Weimann A. Influence of nutritional status on postoperative outcome in patients with colorectal cancer—the emerging role of the microbiome. Innov Surg Sci 2017; 3 (01) 55-64
  • 133 Weimann A, Braga M, Carli F. et al. ESPEN guideline: clinical nutrition in surgery. Clin Nutr 2017; 36 (03) 623-650
  • 134 Hurt RT, McClave SA, Martindale RG. et al. Summary points and consensus recommendations from the international protein summit. Nutr Clin Pract 2017; 32 (Suppl. 01) 142S-151S
  • 135 Kimura Y, Oki E, Ando K, Saeki H, Kusumoto T, Maehara Y. Incidence of venous thromboembolism following laparoscopic surgery for gastrointestinal cancer: a single-center, prospective cohort study. World J Surg 2016; 40 (02) 309-314
  • 136 Krag M, Perner A, Wetterslev J. et al; SUP-ICU Collaborators. Stress ulcer prophylaxis in the intensive care unit: an international survey of 97 units in 11 countries. Acta Anaesthesiol Scand 2015; 59 (05) 576-585
  • 137 Toews I, George AT, Peter JV. et al. Interventions for preventing upper gastrointestinal bleeding in people admitted to intensive care units. Cochrane Database Syst Rev 2018; 6: CD008687
  • 138 Young PJ, Bagshaw SM, Forbes AB. et al; PEPTIC Investigators for the Australian and New Zealand Intensive Care Society Clinical Trials Group, Alberta Health Services Critical Care Strategic Clinical Network, and the Irish Critical Care Trials Group. Effect of stress ulcer prophylaxis with proton pump inhibitors vs histamine-2 receptor blockers on in-hospital mortality among ICU Patients receiving invasive mechanical ventilation: the PEPTIC Randomized Clinical Trial. JAMA 2020; 323 (07) 616-626
  • 139 Heidelbaugh JJ, Kim AH, Chang R, Walker PC. Overutilization of proton-pump inhibitors: what the clinician needs to know. Therap Adv Gastroenterol 2012; 5 (04) 219-232
  • 140 Sedaghat Siyahkal M, Khatami F. Short stay in general intensive care units: is it always necessary?. Med J Islam Repub Iran 2014; 28: 143
  • 141 Barkun A, Bardou M. Proton-pump inhibitor prophylaxis in the ICU—benefits worth the risks?. N Engl J Med 2018; 379 (23) 2263-2264
  • 142 Krag M, Perner A, Wetterslev J. et al; SUP-ICU co-authors. Prevalence and outcome of gastrointestinal bleeding and use of acid suppressants in acutely ill adult intensive care patients. Intensive Care Med 2015; 41 (05) 833-845
  • 143 Vaezi MF, Yang YX, Howden CW. Complications of proton pump inhibitor therapy. Gastroenterology 2017; 153 (01) 35-48
  • 144 Wijarnpreecha K, Thongprayoon C, Chesdachai S, Panjawatanana P, Ungprasert P, Cheungpasitporn W. Associations of proton-pump inhibitors and h2 receptor antagonists with chronic kidney disease: a meta-analysis. Dig Dis Sci 2017; 62 (10) 2821-2827
  • 145 Yang Y, George KC, Shang WF, Zeng R, Ge SW, Xu G. Proton-pump inhibitors use, and risk of acute kidney injury: a meta-analysis of observational studies. Drug Des Devel Ther 2017; 11: 1291-1299
  • 146 Kwon S, Thompson R, Dellinger P, Yanez D, Farrohki E, Flum D. Importance of perioperative glycemic control in general surgery: a report from the Surgical Care and Outcomes Assessment Program. Ann Surg 2013; 257 (01) 8-14