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DOI: 10.1055/s-0041-1726325
Evaluation of Barrett's Esophagus
Abstract
Barrett's esophagus (BE) is the condition in which a metaplastic columnar epithelium that is predisposed to malignancy replaces the stratified squamous epithelium that normally lines the distal esophagus. BE develops as a consequence of chronic gastroesophageal reflux disease and predisposes to esophageal adenocarcinoma (EAC). Several societal guidelines recommend screening and surveillance for BE to reduce the risk of EAC and its related morbidity and mortality. Even among persons undergoing screening and surveillance, a substantial proportion of cases of EAC can be missed. Consequently, the armamentarium for the evaluation of BE has expanded rapidly over the past decade. In this article, we summarize the pathophysiology and diagnosis of BE. We also discuss the latest advancements in the evaluation of BE.
Publication History
Received: 09 October 2020
Accepted: 12 January 2021
Article published online:
18 March 2021
© 2021. Thieme. All rights reserved.
Thieme Medical Publishers, Inc.
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