Subscribe to RSS
DOI: 10.1055/s-0040-1715655
Application of Machine Learning Techniques for Enuresis Prediction in Children
Abstract
Introduction As a subset of artificial intelligence, machine learning techniques (MLTs) may evaluate very large and raw datasets. In this study, the aim is to establish a model by MLT for the prediction of enuresis in children.
Materials and Methods The study included 8,071 elementary school students. A total of 704 children had enuresis. For analysis of data with MLT, another group including 704 nonenuretic children was structured with stratified sampling. Out of 34 independent variables, 14 with high feature values significantly affecting enuresis were selected. A model of estimation was created by training the data.
Results Fourteen independent variables in order of feature importance value were starting age of toilet training, having urinary urgency, holding maneuvers to prevent voiding, frequency of defecation, history of enuresis in mother and father, having child's own room, parent's education level, history of enuresis in siblings, consanguineous marriage, incomplete bladder emptying, frequent voiding, gender, history of urinary tract infection, and surgery in the past. The best MLT algorithm for the prediction of enuresis was determined as logistic regression algorithm. The total accuracy rate of the model in prediction was 81.3%.
Conclusion MLT might provide a faster and easier evaluation process for studies on enuresis with a large dataset. The model in this study may suggest that selected variables with high feature values could be preferred with priority in any screening studies for enuresis. MLT may prevent clinical errors due to human cognitive biases and may help the physicians to be proactive in diagnosis and treatment of enuresis.
Keywords
enuresis - artificial intelligence - machine learning techniques - children - urinary incontinencePublication History
Received: 18 February 2020
Accepted: 01 July 2020
Article published online:
20 August 2020
© 2020. Thieme. All rights reserved.
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany
-
References
- 1 Nørgaard JP, Djurhuus JC, Watanabe H, Stenberg A, Lettgen B. Experience and current status of research into the pathophysiology of nocturnal enuresis. Br J Urol 1997; 79 (06) 825-835
- 2 Caldwell PH, Edgar D, Hodson E, Craig JC. 4. Bedwetting and toileting problems in children. Med J Aust 2005; 182 (04) 190-195
- 3 Bozlu M, Cayan S, Doruk E, Canpolat B, Akbay E. The epidemiology of nocturnal and diurnal enuresis in childhood and adolescence. Turk J Urol 2002; 28: 70-75
- 4 Kaisler SH, Armour F, Espinosa JA, Money W. . Big data: issues and challenges moving forward in: Proceedings of the 46th IEEE Annual Hawaii International Conference on System Sciences (HICC 2013), 2013: 995-1004 . Available at: https://doi.org/10.1109/HICSS.2013.645
- 5 Czarnowski I, Jędrzejowicz P. An approach to data reduction for learning from big datasets: integrating stacking, rotation, and agent population learning techniques. Complexity 2018; (01) 1-13 . Available at: https://doi.org/10.1155/2018/7404627
- 6 Perwej Y. An experiential study of the big data. Int Trans Electr Comp Engineer Syst 2017; 4: 14-25
- 7 Akbal C, Genc Y, Burgu B, Ozden E, Tekgul S. Dysfunctional voiding and incontinence scoring system: quantitative evaluation of incontinence symptoms in pediatric population. J Urol 2005; 173 (03) 969-973
- 8 Sidey-Gibbons JAM, Sidey-Gibbons CJ. Machine learning in medicine: a practical introduction. BMC Med Res Methodol 2019; 19 (01) 64
- 9 De S, Teixeira-Pinto A, Sewell JR, Caldwell PH. Prevalence, patient and consultation characteristics of enuresis in Australian paediatric practice. J Paediatr Child Health 2018; 54 (06) 620-624
- 10 Gür E, Turhan P, Can G. et al. Enuresis: prevalence, risk factors and urinary pathology among school children in Istanbul, Turkey. Pediatr Int 2004; 46 (01) 58-63
- 11 Erdogan A, Akkurt H, Boettjer NK, Yurtseven E, Can G, Kiran S. Prevalence and behavioural correlates of enuresis in young children. J Paediatr Child Health 2008; 44 (05) 297-301
- 12 Butler RJ, Heron J. The prevalence of infrequent bedwetting and nocturnal enuresis in childhood. A large British cohort. Scand J Urol Nephrol 2008; 42 (03) 257-264
- 13 Sahin AH, Sahin H, Budak YU, Sancar S, Tatar H. Prevalence of nocturnal enuresis among primary school children in Bursa, Turkey. Turk Silahli Kuvvetleri Koruyucu Hekim Bul 2012; 11: 139-144
- 14 Weissbach A, Leiberman A, Tarasiuk A, Goldbart A, Tal A. Adenotonsilectomy improves enuresis in children with obstructive sleep apnea syndrome. Int J Pediatr Otorhinolaryngol 2006; 70 (08) 1351-1356
- 15 Acar IC, Zümrütbas AE, Eskicorapci S, Tegin C, Sinik Z, Kara CO. The effects of adenoidectomy and tonsillectomy on monosymptomatic enuresis nocturna. Pamukkale Med J 2011; 4: 9-13
- 16 Khazaie H, Eghbali F, Amirian H, Moradi MR, Ghadami MR. Risk factors of nocturnal enuresis in children with attention deficit hyperactivity disorder. Shanghai Jingshen Yixue 2018; 30 (01) 20-26
- 17 Gunes A, Gunes G, Acik Y, Akilli A. The epidemiology and factors associated with nocturnal enuresis among boarding and daytime school children in southeast of Turkey: a cross sectional study. BMC Public Health 2009; 9: 357
- 18 Somoza Argibay I, Méndez Gallart R, Casal Beloy I, García González M. Urinary incontinence and lower urinary tract dysfunction prevalence in schoolchildren: risk factors [in Spanish]. Cir Pediatr 2019; 32 (03) 145-149
- 19 Fuyama M, Ikeda H, Oyake C, Onuki Y, Watanabe T, Isoyama K. Clinical features of, and association of bladder ultrasound and uroflowmetry with, overactive bladder recovery period in children. Pediatr Int (Roma) 2018; 60 (06) 569-575
- 20 Barone JG, Jasutkar N, Schneider D. Later toilet training is associated with urge incontinence in children. J Pediatr Urol 2009; 5 (06) 458-461
- 21 Söderstrom U, Hoelcke M, Alenius L, Söderling AC, Hjern A. Urinary and faecal incontinence: a population-based study. Acta Paediatr 2004; 93 (03) 386-389
- 22 Penbegül N, Çelik H, Palancı Y. et al. Prevalence of enuresis nocturna among a group of primary school children living in Diyarbakır. Turk J Urol 2013; 39 (02) 101-105
- 23 Gümüş B, Vurgun N, Lekili M, Işcan A, Müezzinoğlu T, Büyuksu C. Prevalence of nocturnal enuresis and accompanying factors in children aged 7-11 years in Turkey. Acta Paediatr 1999; 88 (12) 1369-1372
- 24 Ozden C, Ozdal OL, Altinova S, Oguzulgen I, Urgancioglu G, Memis A. Prevalence and associated factors of enuresis in Turkish children. Int Braz J Urol 2007; 33 (02) 216-222
- 25 Miller DD, Brown EW. Artificial intelligence in medical practice: the question to the answer?. Am J Med 2018; 131 (02) 129-133
- 26 Goodfellow I, Bengio Y, Courville A. Deep Learning. Cambridge, MA, London, UK: The MIT Press; 2016: 96-161
- 27 Rahman SN, Monaghan TF, Weiss JP. Development and validation of a machine learning algorithm for predicting response to anticholinergic medications for overactive bladder syndrome. Obstet Gynecol 2020; 135 (02) 483