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Semin Thromb Hemost 2020; 46(05): 563-586
DOI: 10.1055/s-0039-1701019
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Recent Advances in the Molecular Imaging of Atherosclerosis

Mélusine Larivière
1   University of Tours, Tours, France
,
Samuel Bonnet
2   Centre de Résonance Magnétique des Systèmes Biologiques, UMR 5536, CNRS/Universite de Bordeaux, Bordeaux, France
,
Cyril Lorenzato
2   Centre de Résonance Magnétique des Systèmes Biologiques, UMR 5536, CNRS/Universite de Bordeaux, Bordeaux, France
,
Jeanny Laroche-Traineau
2   Centre de Résonance Magnétique des Systèmes Biologiques, UMR 5536, CNRS/Universite de Bordeaux, Bordeaux, France
,
Florence Ottonès
2   Centre de Résonance Magnétique des Systèmes Biologiques, UMR 5536, CNRS/Universite de Bordeaux, Bordeaux, France
,
Marie-Josée Jacobin-Valat
2   Centre de Résonance Magnétique des Systèmes Biologiques, UMR 5536, CNRS/Universite de Bordeaux, Bordeaux, France
,
Gisèle Clofent-Sanchez
2   Centre de Résonance Magnétique des Systèmes Biologiques, UMR 5536, CNRS/Universite de Bordeaux, Bordeaux, France
› Author Affiliations Funding This study was achieved within the context of the Laboratory of Excellence TRAIL ANR-10-LABX-0057 and was also supported by a public grant from the French “Agence Nationale de la Recherche” (ANR-13-BSV5–0018 SVSE5).
Further Information

Publication History

Publication Date:
30 June 2020 (online)

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Abstract

Atherosclerosis is the major underlying cause of cardiovascular diseases, the prevalence of which is continuously increasing, thus currently standing as the leading global cause of death. This pathology gradually develops over the course of 50 or more years throughout the life of an individual under the influence of a vast number of factors, both environmental and pathophysiological. This wealth of factors has elicited much research into molecular imaging, with purely diagnostic purposes or with the hope of engineering an efficient theranostic tool. To these ends, diverse nanomaterials with desirable, tunable properties have been explored by different teams, as described in this review.

Keywords

molecular imaging - atherosclerosis - theranostic - nanomaterials
 

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