Semin intervent Radiol 2019; 36(03): 183-193
DOI: 10.1055/s-0039-1694714
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Trends in Percutaneous Thermal Ablation Therapies in the Treatment of T1a Renal Cell Carcinomas Rather than Partial Nephrectomy/Radical Nephrectomy

Sepideh Shakeri
1   Department of Radiology, University of California, Los Angeles
,
Steven S. Raman
1   Department of Radiology, University of California, Los Angeles
2   Department of Urology, University of California, Los Angeles
› Author Affiliations
Further Information

Publication History

Publication Date:
19 August 2019 (online)

Abstract

With the increased incidence of stage T1a renal cell carcinoma (RCC) has come the recognition that these lesions tend to be low grade and slow growing, with low probability of metastasis not necessarily requiring surgery. As alternatives to surgery, both active surveillance and ablation have been advocated for the management of selected patients with stage T1a renal cancers due to slow rate of tumor growth and low metastatic potential based on recent epidemiological studies. Thermal ablation also has consistently reported favorable complication and renal preservation rates compared with surgical approaches. However, most studies are single-center case series and meta-analysis of these series and comparative prospective series with long-term follow-up are lacking. The purpose of this article is to review the principal thermal ablation modalities and oncological outcomes for the treatment of stage T1 RCCs with long-term follow-up.

 
  • References

  • 1 Kidney Cancer. Version 4.2019, NCCN Clinical Practice Guidelines in Oncology. https://jnccn.org/view/journals/jnccn/17/5.5/article-p587.xml?rskey=TCZhHZ&result=2 . Accessed July 29, 2019
  • 2 Finelli A, Ismaila N, Russo P. Management of small renal masses: American Society of Clinical Oncology Clinical Practice Guideline Summary. J Oncol Pract 2017; 13 (04) 276-278
  • 3 Motzer RJ, Jonasch E, Agarwal N. , et al. Kidney Cancer, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw 2017; 15 (06) 804-834
  • 4 Ahmad AE, Finelli A. Renal function outcomes following radical or partial nephrectomy for localized renal cell carcinoma: should urologists rely on preoperative variables to predict renal function in the long term?. Eur Urol 2019; 75 (05) 773-774
  • 5 SEER Cancer Stat Facts. Kidney and Renal Pelvis Cancer, Bethesda, MD: National Cancer Institute. Available at: https://seer.cancer.gov/statfacts/html/kidrp.html . Published 2018. Accessed July 20, 2019
  • 6 Atwell TD, Schmit GD, Boorjian SA. , et al. Percutaneous ablation of renal masses measuring 3.0 cm and smaller: comparative local control and complications after radiofrequency ablation and cryoablation. AJR Am J Roentgenol 2013; 200 (02) 461-466
  • 7 Hasegawa T, Yamanaka T, Gobara H. , et al. Radiofrequency ablation versus cryoablation for T1b renal cell carcinoma: a multi-center study. Jpn J Radiol 2018; 36 (09) 551-558
  • 8 McClure T, Pantuck A, Sayer J, Raman S. Efficacy of percutaneous radiofrequency ablation may vary with clear cell renal cell cancer histologic subtype. Abdom Radiol (NY) 2018; 43 (06) 1472-1477
  • 9 Sandbergen L, Guven S, Laguna MP. Can ablation win against partial nephrectomy and become first line therapy in cT1a renal tumours?. Curr Opin Urol 2019; 29 (01) 70-77
  • 10 Krokidis ME, Kitrou P, Spiliopoulos S, Karnabatidis D, Katsanos K. Image-guided minimally invasive treatment for small renal cell carcinoma. Insights Imaging 2018; 9 (03) 385-390
  • 11 Young HH. The early diagnosis and radical cure of carcinoma of the prostate. Being a study of 40 cases and presentation of a radical operation which was carried out in four cases. 1905. J Urol 2002; 168 (03) 914-921
  • 12 Davenport MS, Hu EM, Zhang A. , et al; SAR Disease-Focused Panel on RCC. Standardized report template for indeterminate renal masses at CT and MRI: a collaborative product of the SAR Disease-Focused Panel on Renal Cell Carcinoma. Abdom Radiol (NY) 2019; 44 (04) 1423-1429
  • 13 Guðmundsson E, Hellborg H, Lundstam S, Erikson S, Ljungberg B. ; Swedish Kidney Cancer Quality Register Group. Metastatic potential in renal cell carcinomas ≤7 cm: Swedish Kidney Cancer Quality Register data. Eur Urol 2011; 60 (05) 975-982
  • 14 Ahmed M, Brace CL, Lee Jr FT, Goldberg SN. Principles of and advances in percutaneous ablation. Radiology 2011; 258 (02) 351-369
  • 15 Gervais DA. Cryoablation versus radiofrequency ablation for renal tumor ablation: time to reassess?. J Vasc Interv Radiol 2013; 24 (08) 1135-1138
  • 16 Goldberg SN, Grassi CJ, Cardella JF. , et al; Society of Interventional Radiology Technology Assessment Committee and the International Working Group on Image-guided Tumor Ablation. Image-guided tumor ablation: standardization of terminology and reporting criteria. J Vasc Interv Radiol 2009; 20 (7, Suppl): S377-S390
  • 17 Goldberg SN, Gazelle GS, Mueller PR. Thermal ablation therapy for focal malignancy: a unified approach to underlying principles, techniques, and diagnostic imaging guidance. AJR Am J Roentgenol 2000; 174 (02) 323-331
  • 18 Reyes J, Canter D, Putnam S. , et al. Thermal ablation of the small renal mass: case selection using the R.E.N.A.L.-Nephrometry Score. Urol Oncol 2013; 31 (07) 1292-1297
  • 19 Woldrich JM, Palazzi K, Stroup SP. , et al. Trends in the surgical management of localized renal masses: thermal ablation, partial and radical nephrectomy in the USA, 1998-2008. BJU Int 2013; 111 (08) 1261-1268
  • 20 Ahmed M. ; Technology Assessment Committee of the Society of Interventional Radiology. Image-guided tumor ablation: standardization of terminology and reporting criteria--a 10-year update: supplement to the consensus document. J Vasc Interv Radiol 2014; 25 (11) 1706-1708
  • 21 Campbell S, Uzzo RG, Allaf ME. , et al. Renal mass and localized renal cancer: AUA guideline. J Urol 2017; 198 (03) 520-529
  • 22 Sanchez-Salas R, Desai M. Image-guided therapies for prostate and kidney cancers. World J Urol 2019; 37 (03) 395-396
  • 23 El Dib R, Touma NJ, Kapoor A. Cryoablation vs radiofrequency ablation for the treatment of renal cell carcinoma: a meta-analysis of case series studies. BJU Int 2012; 110 (04) 510-516
  • 24 Kunkle DA, Uzzo RG. Cryoablation or radiofrequency ablation of the small renal mass : a meta-analysis. Cancer 2008; 113 (10) 2671-2680
  • 25 Janzen NK, Perry KT, Han KR. , et al. The effects of intentional cryoablation and radio frequency ablation of renal tissue involving the collecting system in a porcine model. J Urol 2005; 173 (04) 1368-1374
  • 26 Atwell TD, Carter RE, Schmit GD. , et al. Complications following 573 percutaneous renal radiofrequency and cryoablation procedures. J Vasc Interv Radiol 2012; 23 (01) 48-54
  • 27 Atwell TD, Farrell MA, Callstrom MR. , et al. Percutaneous cryoablation of large renal masses: technical feasibility and short-term outcome. AJR Am J Roentgenol 2007; 188 (05) 1195-1200
  • 28 Schmit GD, Thompson RH, Kurup AN. , et al. Usefulness of R.E.N.A.L. nephrometry scoring system for predicting outcomes and complications of percutaneous ablation of 751 renal tumors. J Urol 2013; 189 (01) 30-35
  • 29 Schmit GD, Thompson RH, Kurup AN. , et al. Percutaneous cryoablation of solitary sporadic renal cell carcinomas. BJU Int 2012; 110 (11, Pt B): E526-E531
  • 30 McGahan JP, Brock JM, Tesluk H, Gu WZ, Schneider P, Browning PD. Hepatic ablation with use of radio-frequency electrocautery in the animal model. J Vasc Interv Radiol 1992; 3 (02) 291-297
  • 31 Ward RD, Tanaka H, Campbell SC, Remer EM. 2017 AUA Renal Mass and Localized Renal Cancer Guidelines: imaging implications. Radiographics 2018; 38 (07) 2021-2033
  • 32 Yu NC, Raman SS, Kim YJ, Lassman C, Chang X, Lu DS. Microwave liver ablation: influence of hepatic vein size on heat-sink effect in a porcine model. J Vasc Interv Radiol 2008; 19 (07) 1087-1092
  • 33 Best SL, Park SK, Youssef RF. , et al. Long-term outcomes of renal tumor radio frequency ablation stratified by tumor diameter: size matters. J Urol 2012; 187 (04) 1183-1189
  • 34 Frey GT, Sella DM, Atwell TD. Image-guided renal intervention. Radiol Clin North Am 2015; 53 (05) 1005-1019
  • 35 Sun Y, Wang Y, Ni X. , et al. Comparison of ablation zone between 915- and 2,450-MHz cooled-shaft microwave antenna: results in in vivo porcine livers. AJR Am J Roentgenol 2009; 192 (02) 511-514
  • 36 Bai J, Hu Z, Guan W. , et al. Initial experience with retroperitoneoscopic microwave ablation of clinical T(1a) renal tumors. J Endourol 2010; 24 (12) 2017-2022
  • 37 Floridi C, De Bernardi I, Fontana F. , et al. Microwave ablation of renal tumors: state of the art and development trends. Radiol Med (Torino) 2014; 119 (07) 533-540
  • 38 Chen CN, Liang P, Yu J. , et al. Contrast-enhanced ultrasound-guided percutaneous microwave ablation of renal cell carcinoma that is inconspicuous on conventional ultrasound. Int J Hyperthermia 2016; 32 (06) 607-613
  • 39 Fan W, Li X, Zhang L, Jiang H, Zhang J. Comparison of microwave ablation and multipolar radiofrequency ablation in vivo using two internally cooled probes. AJR Am J Roentgenol 2012; 198 (01) W46-W50
  • 40 Guan W, Bai J, Liu J. , et al. Microwave ablation versus partial nephrectomy for small renal tumors: intermediate-term results. J Surg Oncol 2012; 106 (03) 316-321
  • 41 Ierardi AM, Puliti A, Angileri SA. , et al. Microwave ablation of malignant renal tumours: intermediate-term results and usefulness of RENAL and mRENAL scores for predicting outcomes and complications. Med Oncol 2017; 34 (05) 97
  • 42 Kim SH, Joung JY, Seo HK, Lee KH, Chung J. The effect of predisposing atheroembolic risk factors on renal functional recovery between laparoscopy and open technique in patients with T1-stage renal cell carcinoma who underwent partial nephrectomy: a retrospective comparison study. Jpn J Clin Oncol 2017; 47 (09) 876-882
  • 43 Tourojman M, Kirmiz S, Boelkins B. , et al. Impact of reduced glomerular filtration rate and proteinuria on overall survival of patients with renal cancer. J Urol 2016; 195 (03) 588-593
  • 44 Xing M, Kokabi N, Zhang D, Ludwig JM, Kim HS. Comparative effectiveness of thermal ablation, surgical resection, and active surveillance for T1a renal cell carcinoma: A Surveillance, Epidemiology, and End Results (SEER)-Medicare-linked Population Study. Radiology 2018; 288 (01) 81-90
  • 45 Palumbo C, Cyr SJ, Mazzone E. , et al. Impact of tumor size on cancer specific mortality after local tumor ablation in T1a renal cell carcinoma. J Endourol 2019; 33 (07) 606-613
  • 46 Zhou W, Herwald SE, McCarthy C, Uppot RN, Arellano RS. Radiofrequency ablation, cryoablation, and microwave ablation for T1a renal cell carcinoma: a comparative evaluation of therapeutic and renal function outcomes. J Vasc Interv Radiol 2019; 30 (07) 1035-1042
  • 47 Patel HD, Pierorazio PM, Johnson MH. , et al. Renal functional outcomes after surgery, ablation, and active surveillance of localized renal tumors: a systematic review and meta-analysis. Clin J Am Soc Nephrol 2017; 12 (07) 1057-1069
  • 48 Pierorazio PM, Patel HD, Johnson MH. , et al. Distinguishing malignant and benign renal masses with composite models and nomograms: a systematic review and meta-analysis of clinically localized renal masses suspicious for malignancy. Cancer 2016; 122 (21) 3267-3276
  • 49 Yin X, Cui L, Li F, Qi S, Yin Z, Gao J. Radiofrequency ablation versus partial nephrectomy in treating small renal tumors: a systematic review and meta-analysis. Medicine (Baltimore) 2015; 94 (50) e2255
  • 50 Katsanos K, Mailli L, Krokidis M, McGrath A, Sabharwal T, Adam A. Systematic review and meta-analysis of thermal ablation versus surgical nephrectomy for small renal tumours. Cardiovasc Intervent Radiol 2014; 37 (02) 427-437
  • 51 McClure TD, Chow DS, Tan N, Sayre JA, Pantuck AJ, Raman SS. Intermediate outcomes and predictors of efficacy in the radiofrequency ablation of 100 pathologically proven renal cell carcinomas. J Vasc Interv Radiol 2014; 25 (11) 1682-1688 , quiz 1689
  • 52 Pan XW, Cui XM, Huang H. , et al. Radiofrequency ablation versus partial nephrectomy for treatment of renal masses: a systematic review and meta-analysis. Kaohsiung J Med Sci 2015; 31 (12) 649-658
  • 53 Tanagho YS, Roytman TM, Bhayani SB. , et al. Laparoscopic cryoablation of renal masses: single-center long-term experience. Urology 2012; 80 (02) 307-314
  • 54 Uhlig J, Kokabi N, Xing M, Kim HS. Ablation versus resection for stage 1A renal cell carcinoma: national variation in clinical management and selected outcomes. Radiology 2018; 288 (03) 889-897
  • 55 Moreland AJ, Ziemlewicz TJ, Best SL. , et al. High-powered microwave ablation of T1a renal cell carcinoma: safety and initial clinical evaluation. J Endourol 2014; 28 (09) 1046-1052
  • 56 Shakeri S, Afshari Mirak S, Mohammadian Bajgiran A. , et al. The effect of tumor size and location on efficacy and safety of US- and CT- guided percutaneous microwave ablation in renal cell carcinomas. Abdom Radiol (NY) 2019; 44 (06) 2308-2315
  • 57 Pantelidou M, Challacombe B, McGrath A. , et al. Percutaneous radiofrequency ablation versus robotic-assisted partial nephrectomy for the treatment of small renal cell carcinoma. Cardiovasc Intervent Radiol 2016; 39 (11) 1595-1603
  • 58 Andrews JR, Atwell T, Schmit G. , et al. Oncologic outcomes following partial nephrectomy and percutaneous ablation for cT1 renal masses. Eur Urol 2019; 76 (02) 244-251
  • 59 Choi SH, Kim JW, Kim JH, Kim KW. Efficacy and safety of microwave ablation for malignant renal tumors: an updated systematic review and meta-analysis of the Literature Since 2012. Korean J Radiol 2018; 19 (05) 938-949
  • 60 Rivero JR, De La Cerda III J, Wang H. , et al. Partial nephrectomy versus thermal ablation for clinical stage T1 renal masses: systematic review and meta-analysis of more than 3,900 patients. J Vasc Interv Radiol 2018; 29 (01) 18-29