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Synfacts 2019; 15(11): 1225
DOI: 10.1055/s-0039-1691020
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Synthesis of Esketamine

Contributor(s):
Philip Kocienski
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Publication History

Publication Date:
18 October 2019 (online)

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Key words

esketamine - NMDA receptor antagonist - Noyori asymmetric transfer hydrogenation - [3,3]-sigmatropic shift - allylic cyanate rearrangement - quaternary centers