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Thromb Haemost 1970; 23(01): 001-011
DOI: 10.1055/s-0038-1654113
Originalarbeiten – Original Articles – Travaux Originaux
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Virus Infection and Blood Coagulation[*]

Ch Gagel   1)
1   Department of Medicine and Department of Virology, Justus-Liebig- Universität, Gieβen, Germany
,
M Linder
1   Department of Medicine and Department of Virology, Justus-Liebig- Universität, Gieβen, Germany
,
G Müller-Berghaus
1   Department of Medicine and Department of Virology, Justus-Liebig- Universität, Gieβen, Germany
,
H. G Lasch   2)
1   Department of Medicine and Department of Virology, Justus-Liebig- Universität, Gieβen, Germany
› Author Affiliations
Further Information

Publication History

Publication Date:
24 July 2018 (online)

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Summary

By means of a new model, the fowl plague of chickens, further evidence is given that viruses may trigger blood coagulation. Macroscopically, hemorrhages were observed, whereas microscopic studies revealed platelet and fibrin thrombi in the small vessels of various organs. Hematologic studies demonstrated an increase in the clotting time and a decrease in the activities of clotting factors I, II, VIII and X, and drop in platelet counts. Heparin could diminish the hemorrhages but did not influence the survival time of the animals.

* Supported by Grant Mu 279/1 from the Deutsche Forschungsgemeinschaft, Bad Godesberg, Germany.


1) Medical Thesis by Christina Gagel.


2) Reprint request to : Prof. Lasch, Medizinische Klinik, 63 Gieβen, Germany.


 

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