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Thromb Haemost 1977; 38(03): 0696-0700
DOI: 10.1055/s-0038-1651885
Original Article
Schattauer GmbH

Heparin Neutralizing Activity (HNA) and Antithrombin III in Coronary Artery Disease

G Cella   *
1   Istituto di Semeiotica Medica, Cattedra di Fisiopat. Cardiocircolat., University of Padua Medical School, Padua, Italy
,
R Russo
1   Istituto di Semeiotica Medica, Cattedra di Fisiopat. Cardiocircolat., University of Padua Medical School, Padua, Italy
› Author Affiliations
Further Information

Publication History

Received 31 January 1977

Accepted 02 June 1977

Publication Date:
04 July 2018 (online)

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Summary

Plasma from 14 patients with severe and diffuse coronary atherosclerosis has been compared with that obtained from a normal control group. While a decreased he parin-thrombin clotting time was demonstrated in the patient group, suggesting an increased level of circulating platelet factor 4, there was no significant alteration in plasma antithrombin III level. These results do not support a recent suggestion of a mild chronic intravascular coagulation in atherosclerosis.

* Present Address Thrombosis Unit Research, King’s College Hospital Medical School, Denmark Hill, London, Great Britain


 

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