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Methods Inf Med 1994; 33(01): 129-133
DOI: 10.1055/s-0038-1634972
Original Article
Schattauer GmbH

Interactions between Respiratory, Cardiac and Stepping Rhythms in Decerebrated Cats: Functional Hierarchical Structures of Biological Oscillators

K. Kawahara
1   Department of Electrical and Information Engineering, Faculty of Engineering, Yamagata University, Japan
,
Y. Yamauchi
1   Department of Electrical and Information Engineering, Faculty of Engineering, Yamagata University, Japan
,
K. Niizeki
1   Department of Electrical and Information Engineering, Faculty of Engineering, Yamagata University, Japan
,
T. Yoshioka
1   Department of Electrical and Information Engineering, Faculty of Engineering, Yamagata University, Japan
› Author Affiliations
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Publication History

Publication Date:
08 February 2018 (online)

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Abstract:

Interactions are described of central origin between respiratory, cardiac and stepping rhythms during fictive locomotion in paralyzed, vagotomized, and decerebrated cats. Fictive locomotion was induced by tonic electrical stimulation of the mesencephalic locomotor region (MLR). The coherence between heart beat fluctuation, the efferent discharges of the phrenic, and the lateral gastrocnemius nerves was used to evaluate the strength of the coupling between those three rhythms. The heart beat rhythm was modulated by the centrally generated respiratory and stepping rhythms. The central respiratory rhythm was modulated by the centrally generated stepping rhythm. Based on the present findings, we have proposed a new model concerning the functional hierarchical structures of the three biological oscillators.

Keywords

Fictive Locomotion - Fictive Respiration - Central Pattern Generators - Coherence function
 

  • REFERENCES

  • 1 Kitney Rf, Rompelman O. The study of Heart Rate Variability. Oxford: Oxford University Press; 1980
    Google Scholar
  • 2 Akselrod S, Gordon D, Ubel FA, Shannon DC, Barger AC, Cohen RJ. Power spectrum analysis of heart rate fluctuation: a quantitative probe of beat-to-beat cardiovascular control. Science 1981; 213: 220-2.
    CrossrefPubMedGoogle Scholar
  • 3 Kawahara K, Yamauchi Y. Spectral analysis on fluctuation of heart period in paralyzed, vagotomized, and unanesthetized decerebrate cats. Biol Cybern 1990; 63: 251-6.
    CrossrefPubMedGoogle Scholar
  • 4 Kibby RE, Nugent ST, Marlow RW, MacLead DA, Marble AE. Coupling of cardiac and locomotor rhythms. J Appl Physiol 1989; 66: 323-9.
    CrossrefPubMedGoogle Scholar
  • 5 Udo M, Yoshida T, Nakazumi T, Kinugawa K, Watanabe A. Occurrence of entrainment of heart beat into endurance running pitch and its significance in energy comsumption. In: Kaneko M. ed. Fitness for Aged, Disabled and Industrial Worker. Illinois: Human Kinetics Books; 1990
    Google Scholar
  • 6 Niizeki K, Kawahara K, Miyamoto Y. Interactions among cardiac, respiatory, and locomotor rhythms during cardiolocomotor synchronization. J Appl Physiol 1993; 75: 1815-21.
    CrossrefPubMedGoogle Scholar
  • 7 Kawahara K, Yoshioka T, Yamauchi Y, Niizeki K. Heart beat fluctuation during fictive locomotion in decerebrate cats: locomotorcardiac coupling of central origin. Neurosci Lett 1993; 150: 200-2.
    CrossrefPubMedGoogle Scholar
  • 8 Bechbache DM, Duffin J. The entrainment of breathing frequency by exercise rhythm. J Physiol Lond 1971; 292: 553-61.
    PubMedGoogle Scholar
  • 9 Bramble DM, Carrier DR. Running and breathing in mammals. Science 1983; 219: 251-6.
    CrossrefPubMedGoogle Scholar
  • 10 Iscoe S. Respiratory and stepping frequencies in conscious exercising cats. J Appl Physiol 1981; 51: 835-9.
    CrossrefPubMedGoogle Scholar
  • 11 Kay JDS, Peterson ES, Vejby-Christensen H. Breathing in man during steady state exercise on a bicycle at two pedalling frequencies and during treadmill walking. J Physiol Lond 1975; 251: 645-56.
    CrossrefPubMedGoogle Scholar
  • 12 Kawahara K, Kumagai S, Nakazono Y, Miyamoto Y. Coupling between respiratory and stepping rhythms during locomotion in decerebrate cats. J Appl Physiol 1989; 67: 110-5.
    CrossrefPubMedGoogle Scholar
  • 13 Kawahara K. Coupling between central pattern generators: locomotor-respiratory coupling in decerebrate cats. Trends in Biol Cybern 1990; 01: 179-89.
    PubMedGoogle Scholar
  • 14 Kawahara K, Suzuki M. Interactions between locomotor and respiratory activities during hindlimb stepping on a stationary surface in decerebrate cats. Neurosci Lett 1990; 113: 23-8.
    CrossrefPubMedGoogle Scholar
  • 15 Grillner S. Control of locomotion in biped, tetrapods, and fish. In: Brookhart JM, Mountcastle VB. eds. Handbook of Physiology. (section 1, vol 2), Bethesda: American Physiological Society; 1981: 1179-236.
    Google Scholar
  • 16 Euler von C. Breathing behavior. In: Euler von C, Lagercrantz H. eds. Neurobiology of the Control of Breathing. New York: Raven Press; 1987: 3-8.
    Google Scholar
  • 17 Kawahara K, Nakazono Y, Yamauchi Y, Miyamoto Y. Coupling between respiratory and locomotor rhythms during fictive locomotion in decerebrate cats. Neurosci Lett 1989; 103: 326-32.
    CrossrefPubMedGoogle Scholar
  • 18 Kawahara K, Nakazono Y, Kumagai S, Yamauchi Y, Miyamoto Y. Parallel suppression of extensor muscle tone and respiration by stimulation of pontine dorsal tegmentum in decerebrate cat. Brain Res 1988; 473: 81-90.
    CrossrefPubMedGoogle Scholar
  • 19 Kawahara K, Suzuki M. Descending inhibitory pathway responsible for simultaneous suppression of postural tone and respiration in decerebrate cats. Brain Res 1991; 538: 303-9.
    CrossrefPubMedGoogle Scholar
  • 20 Cohen MI. Respiratory periodicity in the paralyzed, vagotomized cat: hypocapnic polypnea. Am J Physiol 1964; 206: 845-54.
    PubMedGoogle Scholar
  • 21 Snider RS, Niemer WTA. Stereotaxic Atlas of the Cat Brain. Chicago: University of Chicago Press; 1961
    Google Scholar
  • 22 Kawahara K, Yoshioka T, Yamauchi Y, Niizeki K. Interactions between cardiac, respiratory, and locomotor rhythms during fictive locomotion in decerebrate cats. Neurosci Res 1992; (Suppl. 17) S278.
    PubMedGoogle Scholar