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DOI: 10.1055/s-0038-1632836
Hirntumortherapie
Ein UpdateBrain tumour therapyAn updatePublication History
Eingegangen am:
31 August 2009
angenommen am:
02 September 2009
Publication Date:
03 February 2018 (online)
![](https://www.thieme-connect.de/media/10.1055-s-00034915/201004/lookinside/thumbnails/10-1055-s-0038-1632836_de-1.jpg)
Zusammenfassung
Die Therapie der primären Hirntumoren erfährt derzeit einen neuen Schub durch dia-gnostisch und therapeutisch relevante Erkenntnisse im molekularen Bereich. Es werden Defekte der Wachstumsregulation definiert, die in ähnlicher Form auch bei anderen malignen Erkrankungen vorkommen. Gegen diese definierten Defekte werden immer mehr zielgerichtete Therapien mit spezifischen Hemmstoffen verfügbar. Dadurch eröffnen sich neue Perspektiven, die Therapie zu verbessern.
Summary
Therapy of primary brain tumours gets a new impact by new insights into the molecular mechanisms of disturbed cell growth. It is possible, to define specific defects of cellular signal transduction cascades, which often use similar in other malignant tumours. Thus specific inhibitors available for other tumours may also be applied in gliomas providing new therapeutic options.
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