Lumbar intervertebral disc replacement using bioabsorbable self-reinforced poly-L-lactide full-threaded screws, or cylindrical implants of polylactide polymers, bioactive glass and Polyactive™

T. Palmgren; P. Ylinen; R.-M. Tulamo; M. Kellomäki; P. Türmälä; P. Rokkanen

doi:10.1055/s-0038-1632777

Veterinary and Comparative Orthopaedics and Traumatology, Table of Contents

Vet Comp Orthop Traumatol 2003; 16(03): 138-144
DOI: 10.1055/s-0038-1632777

Original Research

Schattauer GmbH

Lumbar intervertebral disc replacement using bioabsorbable self-reinforced poly-L-lactide full-threaded screws, or cylindrical implants of polylactide polymers, bioactive glass and Polyactive™

T. Palmgren

¹Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Helsinki, Finland

,

P. Ylinen

¹Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Helsinki, Finland

²ORTON Orthopedic Hospital, Invalid Foundation, Helsinki, Finland

,

R.-M. Tulamo

¹Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Helsinki, Finland

³Department of Surgery, Faculty of Veterinary Medicine, Helsinki University, Helsinki, Finland

,

M. Kellomäki

¹Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Helsinki, Finland

⁴Institute of Biomaterials, Tampere University of Technology, Tampere, Finland

,

P. Türmälä

¹Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Helsinki, Finland

⁴Institute of Biomaterials, Tampere University of Technology, Tampere, Finland

,

P. Rokkanen

¹Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Helsinki, Finland

› Author Affiliations

Abstract

Summary

Intervertebral disc surgery leads to changes in the segmental anatomy and mobility, and subsequently to degenerative changes in the lumbar spine. Artificial intervertebral disc implants sufficient to replace the human lumbar intervertebral disc have been developed and the requirements for these defined. This is to our knowledge the first study on bioabsorbable intervertebral disc replacement implants. SR-PLLA screws, previously used in orthopaedic internal fixations, and cylindrical implants, specifially developed for this experimental preliminary study, were used to replace lumbar intervertebral discs of growing pigs. After a 15-week follow-up period, the radiological and histological changes in the intervertebral spaces were analyzed. The cylindrical implants were able to prevent narrowing of discectomied spaces, and tissue regeneration in the intervertebral space was induced and occured simultaneously with degradation of the implant.

Keywords

Bioabsorbable - intervertebral disc implant

Full Text

References

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