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DOI: 10.1055/s-0038-1629278
Therapieansätze bei hypothalamer Adipositas
Therapeutic options in hypothalamic obesityPublication History
Eingereicht am: 23 March 2015
angenommen am: 02 April 2015
Publication Date:
29 January 2018 (online)
![](https://www.thieme-connect.de/media/10.1055-s-00034917/201504/lookinside/thumbnails/10-1055-s-0038-1629278_de-1.jpg)
Zusammenfassung
Die Pathogenese der hypothalamen Adipositas ist vielfältig und beinhaltet neben der Hyperphagie auch einen vermindertem Grundumsatz, autonome Fehlregulationen als auch Schlafstörungen und eine verminderte Mobilität. Resultierend daraus existieren verschiedene Therapiekonzepte. Bisher konnte jedoch weder für den konservativ-medikamentösen Ansatz als auch für den bariatrisch-chirurgischen Therapieansatz eine allgemeingültige Empfehlung gegeben werden. Am vorliegenden Fallbericht möchten wir noch einmal die Komplexität der Erkrankungen und die Schwierigkeit sinnvoller Therapieentscheidungen darstellen.
Summary
The pathogenesis of hypothalamic obesity is complex. It includes in addition to hyperphagia a diminished basal metabolic rate, autonomic dysregulation, sleep disturbances and decreased mobility. This fact has resulted in various therapeutic strategies. To date, however, a general treatment concept or recommendation does not exist, neither for the conservative medical approach nor for bariatric surgery. With this case report we want to point out the complexity of the disorder as well as the challenge of establishing effective therapeutic decisions.
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