Nuklearmedizin 2016; 55(05): N44-N45
DOI: 10.1055/s-0037-1616498
Case report
Schattauer GmbH

Strong [68Ga]PSMA-HBED-CC accumulation in non-cancerous prostate tissue surrounding a PSMA-negative prostate carcinoma recurrence

Frederik A. Verburg
1   Department of Nuclear Medicine, RWTH University Hospital Aachen, Germany
2   Department of Nuclear Medicine, Maastricht UMC, the Netherlands
,
Florian F. Behrendt
1   Department of Nuclear Medicine, RWTH University Hospital Aachen, Germany
,
Felix M. Mottaghy
1   Department of Nuclear Medicine, RWTH University Hospital Aachen, Germany
2   Department of Nuclear Medicine, Maastricht UMC, the Netherlands
,
David Pfister
3   Department of Urology, RWTH University Hospital Aachen, Germany
,
Florian Steib
4   Department of Pathology, RWTH University Hospital Aachen, Germany
,
Ruth Knuechel
4   Department of Pathology, RWTH University Hospital Aachen, Germany
› Author Affiliations
Further Information

Publication History

received: 08 January 2016

accepted: 12 January 2016

Publication Date:
06 January 2018 (online)

 

 
  • References

  • 1 Afshar-Oromieh A, Avtzi E, Giesel FL. et al. The diagnostic value of PET/CT imaging with the 68Ga-labelled PSMA ligand HBED-CC in the diagnosis of recurrent prostate cancer. Eur J Nucl Med Mol Imaging 2015; 42: 197-209.
  • 2 Bostwick DG, Pacelli A, Blute M. et al. Prostate specific membrane antigen expression in prostatic intraepithelial neoplasia and adenocarcinoma: a study of 184 cases. Cancer 1998; 82: 2256-2261.
  • 3 Krohn T, Verburg FA, Pufe T. et al. [68Ga]PSMA-HBED uptake mimicking lymph node metastasis in coeliac ganglia: an important pitfall in clinical practice. Eur J Nucl Med Mol Imaging 2015; 42: 210-214.
  • 4 Silver DA, Pellicer I, Fair WR. et al. Prostate-specific membrane antigen expression in normal and malignant human tissues. Clin Cancer Res 1997; 3: 81-85.
  • 5 Verburg FA, Pfister D, Heidenreich A. et al. Extent of disease in recurrent prostate cancer determined by [68Ga]PSMA-HBED-CC PET/CT in relation to PSA levels, PSA doubling time and Gleason score. Eur J Nucl Med Mol Imaging. 2015 DOI (PMID: 10.1007/s00259-015-3240-1)