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Synfacts 2019; 15(05): 0563
DOI: 10.1055/s-0037-1612506
Chemistry in Medicine and Biology
© Georg Thieme Verlag Stuttgart · New York

Ring-Closing Metathesis in the Synthesis of Simeprevir

Contributor(s):
Dirk Trauner
,
Belinda Hetzler
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Publication History

Publication Date:
15 April 2019 (online)

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Key words

ring-closing metathesis - HCV Inhibitor - macrocyclization - NMR analysis - commercial scale