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Synfacts 2017; 13(02): 0126
DOI: 10.1055/s-0036-1589890
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Asymmetric Synthesis of an 11β-HSD-1 Inhibitor

Contributor(s):
Philip Kocienski
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Publication History

Publication Date:
18 January 2017 (online)

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Key words

11β-hydroxysteroid dehydrogenase inhibitor - asymmetric hydrogenation - indenopiperidine ring formation - C–H arylation - palladium catalysis - iridium catalysis