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Semin Hear 2016; 37(01): 001-008
DOI: 10.1055/s-0035-1570334
DOI: 10.1055/s-0035-1570334
Summary of the N1-P2 Cortical Auditory Evoked Potential to Estimate the Auditory Threshold in Adults
Further Information
Publication History
Publication Date:
04 February 2016 (online)
![](https://www.thieme-connect.de/media/sih/201601/lookinside/thumbnails/10-1055-s-0035-1570334_00689-1.jpg)
Abstract
This article introduces the cortical auditory evoked potential (CAEP) and describes the use of the N1-P2 response complex as an objective predictor of hearing threshold in adults and older children. The generators of the CAEP are discussed together with issues of maturation, subject factors, and stimuli and recording parameters for use in the clinic. The basic methods for response identification are outlined and suggestions are made for determining the CAEP threshold. Clinical applications are introduced and the accuracy of the CAEP as an estimator of hearing threshold is given. Finally, a case study provides an example of the technique in the context of medicolegal assessment.
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References
- 1 Hyde M. The N1 response and its applications. Audiol Neurootol 1997; 2 (5) 281-307
- 2 Alberti PW, Hyde ML, Riko K. Exaggerated hearing loss in compensation claimants. J Otolaryngol 1987; 16 (6) 362-366
- 3 Coles RR, Mason SM. The results of cortical electric response audiometry in medico-legal investigations. Br J Audiol 1984; 18 (2) 71-78
- 4 Hone SW, Norman G, Keogh I, Kelly V. The use of cortical evoked response audiometry in the assessment of noise-induced hearing loss. Otolaryngol Head Neck Surg 2003; 128 (2) 257-262
- 5 Prasher D, Mula M, Luxon L. Cortical evoked potential criteria in the objective assessment of auditory threshold: a comparison of noise induced hearing loss with Ménière's disease. J Laryngol Otol 1993; 107 (9) 780-786
- 6 Lightfoot G, Kennedy V. Cortical electric response audiometry hearing threshold estimation: accuracy, speed, and the effects of stimulus presentation features. Ear Hear 2006; 27 (5) 443-456
- 7 Stapells D. Cortical event-related potentials to auditory stimuli. In: Katz J, , ed. Handbook of Clinical Audiology. 5th ed.. Philadelphia: Lippincott Williams & Wilkins; 2002
- 8 Liégeois-Chauvel C, Musolino A, Badier JM, Marquis P, Chauvel P. Evoked potentials recorded from the auditory cortex in man: evaluation and topography of the middle latency components. Electroencephalogr Clin Neurophysiol 1994; 92 (3) 204-214
- 9 Howard MA, Volkov IO, Mirsky R , et al. Auditory cortex on the human posterior superior temporal gyrus. J Comp Neurol 2000; 416 (1) 79-92
- 10 Sharma A, Dorman MF, Spahr AJ. A sensitive period for the development of the central auditory system in children with cochlear implants: implications for age of implantation. Ear Hear 2002; 23 (6) 532-539
- 11 Pratt H, Lightfoot G. Physiological mechanisms underlying MLRs and cortical EPs. In: Tremblay KL, Burkard RF, , eds. Translational Perspectives in Auditory Neuroscience; Physiological Assessment of Audition. San Diego, CA: Plural Publishing; 2012
- 12 Wunderlich JL, Cone-Wesson BK, Shepherd R. Maturation of the cortical auditory evoked potential in infants and young children. Hear Res 2006; 212 (1–2) 185-202
- 13 Mast T, Watson C. Attention and auditory evoked responses to low detectability signals. Percept Psychophys 1968; 4: 237-240
- 14 Keating LW, Ruhm HB. Within average variability of the acoustically evoked response. J Speech Hear Res 1971; 14 (1) 179-188
- 15 Ornitz EM, Ritvo ER, Carr EM, Panman LM, Walter RD. The variability of the auditory averaged evoked response during sleep and dreaming in children and adults. Electroencephalogr Clin Neurophysiol 1967; 22 (6) 514-524
- 16 Campbell KB, Colrain IM. Event-related potential measures of the inhibition of information processing: II. The sleep onset period. Int J Psychophysiol 2002; 46 (3) 197-214
- 17 Pantev C, Eulitz C, Hampson S, Ross B, Roberts LE. The auditory evoked “off” response: sources and comparison with the “on” and the “sustained” responses. Ear Hear 1996; 17 (3) 255-265
- 18 Jones SJ, Longe O, Vaz Pato M. Auditory evoked potentials to abrupt pitch and timbre change of complex tones: electrophysiological evidence of “streaming”?. Electroencephalogr Clin Neurophysiol 1998; 108 (2) 131-142
- 19 Cody DT, Klass DW. Cortical audiometry. Potential pitfalls in testing. Arch Otolaryngol 1968; 88 (4) 396-406
- 20 Weber BA. Habituation and dishabituation of the averaged auditory evoked response. J Speech Hear Res 1970; 13 (2) 387-394
- 21 McCandless GA, Best L. Summed evoked responses using pure-tone stimuli. J Speech Hear Res 1966; 9 (2) 266-272
- 22 Skinner PH, Jones HC. Effects of signal duration and rise time on the auditory evoked potential. J Speech Hear Res 1968; 11 (2) 301-306
- 23 Bardy F, Van Dun B, Dillon H. Bigger is better: Increasing cortical auditory response amplitude via stimulus spectral complexity. Ear Hear 2015; 36 (6) 677-687
- 24 Ponton C, Eggermont JJ, Khosla D, Kwong B, Don M. Maturation of human central auditory system activity: separating auditory evoked potentials by dipole source modeling. Clin Neurophysiol 2002; 113 (3) 407-420
- 25 Nelson DA, Lassman FM, Hoel RL. The effects of variable-interval and fixed-interval signal presentation schedules on the auditory evoked response. J Speech Hear Res 1969; 12 (1) 199-209
- 26 Davis H, Zerlin S. Acoustic relations of the human vertex potential. J Acoust Soc Am 1966; 39 (1) 109-116
- 27 Rapin I. Practical considerations in using the evoked potential technique in audiometry. Acta Otol 1964; 206: 117-122
- 28 Appleby S. The slow vertex maximal sound evoked response in infants. Acta Otol 1964; 206: 146-152
- 29 Woods DL, Elmasian R. The habituation of event-related potentials to speech sounds and tones. Electroencephalogr Clin Neurophysiol 1986; 65 (6) 447-459
- 30 Rothman HH, Davis H, Hay IS. Slow evoked cortical potentials and temporal features of stimulation. Electroencephalogr Clin Neurophysiol 1970; 29 (3) 225-232
- 31 Butler RA. The influence of spatial separation of sound sources on the auditory evoked response. Neuropsychologia 1972; 10 (2) 219-225
- 32 Butler RA. Effect of changes in stimulus frequency and intensity on habituation of the human vertex potential. J Acoust Soc Am 1968; 44 (4) 945-950
- 33 Picton TW, Goodman WS, Bryce DP. Amplitude of evoked responses to tones of high intensity. Acta Otolaryngol 1970; 70 (2) 77-82
- 34 Ross B, Lütkenhöner B, Pantev C, Hoke M. Frequency-specific threshold determination with the CERAgram method: basic principle and retrospective evaluation of data. Audiol Neurootol 1999; 4 (1) 12-27
- 35 Carter L, Golding M, Dillon H, Seymour J. The detection of infant cortical auditory evoked potentials (CAEPs) using statistical and visual detection techniques. J Am Acad Audiol 2010; 21 (5) 347-356
- 36 Albera R, Canale G, Magnano M , et al. [Relations between pure-tone audiometry and cortical evoked auditory potentials]. Acta Otorhinolaryngol Ital 1991; 11 (6) 551-562
- 37 Tsu B, Wong LL, Wong EC. Accuracy of cortical evoked response audiometry in the identification of non-organic hearing loss. Int J Audiol 2002; 41 (6) 330-333