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Synlett 2015; 26(18): 2485-2490
DOI: 10.1055/s-0035-1560635
DOI: 10.1055/s-0035-1560635
synpacts
The Biosynthesis and Biomimetic Synthesis of Merochlorins A and B
Further Information
Publication History
Received: 27 July 2015
Accepted after revision: 04 September 2015
Publication Date:
30 September 2015 (online)


Abstract
The interplay between biosynthetic studies and biomimetic synthesis is discussed in the context of the merochlorin family of marine natural products. Total syntheses of merochlorin A by our group and merochlorin B by the Trauner group are presented alongside the biosynthetic studies of Moore and co-workers. The common theme is the generation of complex polycyclic ring systems by oxidative dearomatization–cyclization cascade reactions.