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DOI: 10.1055/s-0034-1382902
Effect of Quercetin-3-O-Sambubioside Isolated from Eucommia ulmoides Male Flowers on Spontaneous Activity and Convulsion Rate in Mice
Publication History
received 22 December 2013
revised 19 June 2014
accepted 20 June 2014
Publication Date:
06 August 2014 (online)
![](https://www.thieme-connect.de/media/plantamedica/201412/lookinside/thumbnails/10.1055-s-0034-1382902-1.jpg)
Abstract
The purpose of this study was to evaluate the effects of quercetin-3-O-sambubioside on the neural system. Quercetin-3-O-sambubioside is a monomeric compound found in Eucommia ulmoides male flowers from which it was extracted using a system solvent method. In the experiments, spontaneous activity and convulsion rate in mice were recorded, and quercetin-3-O-sambubioside shows eminent effects similar to nikethamide on increasing spontaneous activity and stimulating the nerve center to enhance excitement. These findings are indicative of the powerful ability of quercetin-3-O-sambubioside to promote the stimulation of the nerve center.
Key words
Eucommia ulmoides - Eucommiaceae - quercetin-3-O-sambubioside - neural excitation - excitement-
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