Copper-Catalyzed Tandem Synthesis of Pentasubstituted Pyridines from Sulfonoketenimides and 2-Aminoprop-1-ene-1,1,3-tricarbonitrile

Abstract

Fully substituted pyridines were synthesized in moderate to good yields in a one-pot process by the copper-catalyzed sequential reaction of sulfonyl azides with terminal alkynes and 2-aminoprop-1-ene-1,1,3-tricarbonitrile at room temperature.

Keywords

pyridines - cyclizations - tandem reactions - copper - catalysis

• References and Notes

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