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Klin Monbl Augenheilkd 2013; 230(4): 443-444
DOI: 10.1055/s-0032-1328389
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Georg Thieme Verlag KG Stuttgart · New York

Conjunctival Extrascleral Extension of a Myeloid Sarcoma: a Clinicopathological Case Report

Episkleralinfiltration im myeloiden Sarkom
A. P. Moulin
1   Jules-Gonin Eye Hospital, University of Lausanne, Switzerland
,
D. Védy
2   Grand Rue 3, 1820 Montreux, Switzerland
,
Y. Guex-Crosier
1   Jules-Gonin Eye Hospital, University of Lausanne, Switzerland
,
L. Zografos
1   Jules-Gonin Eye Hospital, University of Lausanne, Switzerland
,
A. Schalenbourg
1   Jules-Gonin Eye Hospital, University of Lausanne, Switzerland
› Author Affiliations
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Publication History

Publication Date:
29 April 2013 (online)

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Introduction

Myeloid sarcoma (granulocytic sarcoma) is an extramedullary tissue infiltration by blastic cells in acute myelogenous leukaemia (AML) or myeloproliferative/myelodysplastic syndromes in blastic transformation. As the neoplastic cells contain myeloperoxidase conferring a greenish appearance to the tissue, these tumours used to be called “chloroma” [1]. In ophthalmology, they tend to develop in childrenʼs’ orbits, arising from the adjacent orbital bones. Conjunctival infiltration has only been published in less than 20 cases [2], [3], [4], [5], [6], [7], [8].

We report a myeloid sarcoma in a patient with secondary AML initially diagnosed as a scleritis, where ultrasound biomicroscopy (UBM) demonstrating a solid subconjunctival infiltration extending from the ciliary body, prompted for a conjunctivo-scleral biopsy to establish the diagnosis and treatment.

 

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