Dtsch Med Wochenschr 2011; 136(33): 1675
DOI: 10.1055/s-0031-1281574
Pro & Contra | Commentary
Rheumatologie
© Georg Thieme Verlag KG Stuttgart · New York

Können Biologika bei rheumatoider Arthritis nach Erreichen einer Remission abgesetzt werden? Contra

Discontinuation of biologicals in rheumatoid arthritis after acquiring remission? NoM. Grünke1
  • 1Rheumaeinheit, Klinikum der Universität München
Further Information

Publication History

Publication Date:
10 August 2011 (online)

Literatur

  • 1 Askling J. The risk of malignancies in RA patients treated with biologics.  Z Rheumatol. 2010;  69 774-779
  • 2 Braun J, Barraliakos X, Listing J. et al . Persistent clinical efficacy and safety of anti-tumour necrosis factor a therapy with infliximab in patients with ankylosing spondylitis: evidence for different types of response over 5 years.  Ann Rheum Dis. 2008;  67 340-345
  • 3 Chatzidionysiou K, van Vollenhoven R F. When to initiate and discontinue biologic treatments for rheumatoid arthritis?.  J Intern Med. 2011;  269 614-625
  • 4 Saleem B, Keen H, Goeb V. et al . Patients with RA in remission on TNF blockers: when and in whom can TNF blocker therapy be stopped?.  Ann Rheum Dis. 2010;  69 1636-1642
  • 5 van den Broek M, Klarenbeek N B, Dirven L. et al . Discontinuation of infliximab and potential predictors of persistent low disease activity in patients with early rheumatoid arthritis and disease activity score-steered therapy: subanalysis of the BeSt study.  Ann Rheum Dis. 2011;  70 1389-1394

Dr. Mathias Grünke

Oberarzt
Studienambulanz der Rheumaeinheit
Klinikum der Universität München

Pettenkoferstr. 8a

80336 München

Phone: 089 5160 3473

Fax: +49 89 5160 3719

Email: Mathias.Gruenke@med.uni-muenchen.de