Exp Clin Endocrinol Diabetes 2011; 119(4): 201-207
DOI: 10.1055/s-0031-1271691
Article

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Prevalence of Thyroid Dysfunction in Patients with Type 2 Diabetes

J. J. Díez1 , P. Sánchez2 , P. Iglesias1 , 3
  • 1Department of Endocrinology, Hospital Ramón y Cajal, Madrid, Spain.
  • 2Department of Endocrinology, Hospital Gregorio Marañón, Madrid, Spain
  • 3Department of Endocrinology, Hospital General, Segovia, Spain
Further Information

Publication History

received 08.11.2010 first decision 29.12.2010

accepted 17.01.2011

Publication Date:
04 April 2011 (online)

Abstract

Aim: Assess the prevalence of thyroid dysfunction in patients with type 2 diabetes (T2D) in Segovia (Spain).

Methods: A screening program for thyroid dysfunction including all patients with T2D attending the diabetes clinic at the Hospital General de Segovia was performed from 2003 to 2005.

Results: 318 patients (191 women, aged 29–89 yr, median duration of diabetes 8 yr) attended the diabetes clinic. The number of patients with thyroid dysfunction and their respective prevalences were: overt hyperthyroidism, 11 (3.5%); subclinical hyperthyroidism, 10 (3.1%); overt hypothyroidism, 48 (15.1%), and subclinical hypothyroidism, 34 patients (10.7%). The screening program detected the following cases of newly diagnosed thyroid dysfunction: subclinical hyperthyroidism, 5 (1.6%); overt hypothyroidism, 6 (1.9%), and subclinical hypothyroidism, 20 patients (6.3%). Therefore, total thyroid dysfunction was present in 32.4% (95% CI, 27.3–37.5%), and newly diagnosed thyroid dysfunction was present 9.7% (95% CI, 6.5–13.0%) of the patients. Logistic regression analysis showed that there were no significant relationships between the presence of thyroid dysfunction and duration of diabetes, hemoglobin A1c levels, and the presence of diabetic complications.

Conclusion: This screening program detected new cases of thyroid dysfunction in ∼10% of diabetic subjects. However, we could not identify any diabetes-related clinical parameter with predictive value on the presence of thyroid dysfunction.

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Correspondence

J. J. Díez

Department of Endocrinology

Hospital Ramón y Cajal

Carretera de Colmenar km 9

Spain

Phone: +34/9133/684 76

Email: jdiez.hrc@salud.madrid.org