Synfacts 2010(5): 0599-0599  
DOI: 10.1055/s-0029-1219746
Organo- and Biocatalysis
© Georg Thieme Verlag Stuttgart ˙ New York

An Ionic Network as Catalyst for Asymmetric Benzylation

Contributor(s): Benjamin List, Lars Ratjen
S. Itsuno*, D. K. Paul, M. A. Salam, N. Haraguchi
Toyohashi University of Technology, Japan
Further Information

Publication History

Publication Date:
22 April 2010 (online)

Significance

The authors report the synthesis of binuclear cinchonidinium-based catalysts, such as 1, and their subsequent incorporation into ionic networks 2. These chiral ionic polymers were obtained by counter-anion exchange of the monomeric binuclear species with 2,6-naphthalene-­disulfonates. The assembled high molecular weight catalysts, with an impressively high average molecular weight, proved to be very efficient for the asymmetric benzylation of N-diphenylmethyl-ideneglycine tert-butyl ester.