Download PDF
Synfacts 2009(10): 1071-1071  
DOI: 10.1055/s-0029-1217867
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of (+)-Omaezakianol

Contributor(s): Philip Kocienski, Arndt W. Schmidt
Y. Morimoto*, T. Okita, H. Kambara
Osaka City University, Japan
Further Information

Publication History

Publication Date:
22 September 2009 (online)

    Permissions and Reprints

Significance

The triterpene polyether (+)-oma-ezakianol was isolated from the red alga Laurencia omaezakiana Masuda. The relative and absolute structure was predicted by comparison with related compounds. Herein the first asymmetric total synthesis of (+)-omaezakianol is reported, confirming the predicted structure.