Desmopressin (Minirin®) beim schweren Trauma – eine Fallbeschreibung

Zusammenfassung

Blutungen und Gerinnungsstörungen sind beim Traumapatienten nicht selten und erfordern eine frühzeitige und konsequente Therapie. Unter den oft vorherrschenden pathophysiologischen Bedingungen beim schweren Trauma wie Hypothermie, Azidose und Koagulopathie stellt Desmopressin eine mögliche Option bei der Behandlung von diffusen Blutungen dar. Wir berichten über 2 Patienten, die nach schwerem Trauma diffus bluteten und bei denen aus Sicht der Autoren nach der Desmopressingabe die Blutung deutlich nachließ beziehungsweise sistierte. Weiterhin wird der mögliche Nutzen von Desmopressin bei diesen Patienten diskutiert.

Abstract

Bleeding and clotting disturbances are not uncommon in trauma patients and require an early and consequent therapy. Under the prevalent pathophysiological circumstances of hypothermia, acidosis and clotting disturbances, desmopressin seems to be a possible option to control diffuse bleeding. We report about 2 trauma patients with diffuse bleeding and in whom desmopressin was used successfully to control bleeding from the point of view of the authors. We discuss the advantages and disadvantages of desmopressin in the 2 patients.

Schlüsselwörter

Trauma - Blutung - Gerinnungsstörungen - Desmopressin - Azidose - Hypothermie

Key words

trauma - bleeding - clotting disturbances - desmopressin - acidosis - hypothermia

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