Dtsch Med Wochenschr 2008; 133(41): 2099-2102
DOI: 10.1055/s-0028-1091244
Aktuelle Diagnostik & Therapie | Review article
Nuklearmedizin, Onkologie
© Georg Thieme Verlag KG Stuttgart · New York

Selektive interne Radiotherapie bei fortgeschrittenen Lebertumoren und Metastasen

Selective internal radiation therapy for primary and secondary liver tumorsR.-T Hoffmann1 , T. F. Jakobs1 , K. Tatsch2 , M. F. Reiser1
  • 1Institut für Klinische Radiologie – Klinikum der Universität München, Campus Großhadern
  • 2Klinik und Poliklinik für Nuklearmedizin – Klinikum der Universität München, Campus Großhadern
Further Information

Publication History

eingereicht: 26.3.2008

akzeptiert: 30.7.2008

Publication Date:
23 September 2008 (online)

Literatur

  • 1 Jakobs T F, Hoffmann R T, Poepperl G, Schmitz A, Lutz J, Koch W, Tatsch K, Lubiensky A, Reiser M F, Helmberger T. Mid-term results in otherwise treatment refractory primary or secondary liver confined tumours treated with selective internal radiation therapy (SIRT) using (90)Yttrium resin-microspheres.  Eur Radiol. 2006;  17 1320-1330
  • 2 Kennedy A S, Coldwell D, Nutting C, Murthy R, Wertman Jr D E, Loehr S P, Overton C, Meranze S, Niedzwiecki J, Sailer S. Resin 90Y-microsphere brachytherapy for unresectable colorectal liver metastases: modern USA experience.  Int J Radiat Oncol Biol Phys. 2006;  65 412-425
  • 3 Kulik L M, Atassi B, van Holsbeeck L, Souman T, Lewandowski R J, Mulcahy M F, Hunter R D, Nemcek Jr A A, Abecassis M M, Haines 3rd K G, Salem R. Yttrium-90 microspheres (TheraSphere) treatment of unresectable hepatocellular carcinoma: downstaging to resection, RFA and bridge to transplantation.  J Surg Oncol. 2006;  94 572-586
  • 4 Lau W Y, Ho S, Leung T W, Chan M, Ho R, Johnson P J, Li A K. Selective internal radiation therapy for nonresectable hepatocellular carcinoma with intraarterial infusion of 90yttrium microspheres.  Int J Radiat Oncol Biol Phys. 1998;  40 583-592
  • 5 Leung T W, Lau W Y, Ho S K, Ward S C, Chow J H, Chan M S, Metreweli C, Johnson P J, Li A K. Radiation pneumonitis after selective internal radiation treatment with intraarterial 90yttrium-microspheres for inoperable hepatic tumors.  Int J Radiat Oncol Biol Phys. 1995;  33 919-924
  • 6 Leung W T, Lau W Y, Ho S K, Chan M, Leung N W, Lin J, Metreweli C, Johnson P J, Li A K. Measuring lung shunting in hepatocellular carcinoma with intrahepatic-arterial technetium-99m macroaggregated albumin.  J Nucl Med. 1994;  35 70-73
  • 7 Salem R, Thurston K G. Radioembolization with 90yttrium microspheres: a state-of-the-art brachytherapy treatment for primary and secondary liver malignancies. Part 1: Technical and methodologic considerations.  J Vasc Interv Radiol. 2006;  17 1251-1278
  • 8 Salem R, Thurston K G. Radioembolization with 90yttrium microspheres: a state-of-the-art brachytherapy treatment for primary and secondary liver malignancies. Part 2: special topics.  J Vasc Interv Radiol. 2006;  17 1425-1439
  • 9 Salem R, Thurston K G. Radioembolization with yttrium-90 microspheres: a state-of-the-art brachytherapy treatment for primary and secondary liver malignancies: part 3: comprehensive literature review and future direction.  J Vasc Interv Radiol. 2006;  17 1571-1593
  • 10 Yip D, Allen R, Ashton C, Jain S. Radiation-induced ulceration of the stomach secondary to hepatic embolization with radioactive yttrium microspheres in the treatment of metastatic colon cancer.  J Gastroenterol Hepatol. 2004;  19 347-349

Dr. med. Ralf-Thorsten Hoffmann

Institut für Klinische Radiologie, Klinikum der Universität München, Campus Großhadern

Marchioninistr. 15

81377 München

Phone: +49 89 7095-3620

Fax: +49 89 7095-8832

Email: rthoffma@med.uni-muenchen.de