Synlett 2008(18): 2874-2876  
DOI: 10.1055/s-0028-1083569
LETTER
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of a Trihydroxylated Aminoazepane from d-Glucitol by an Intramolecular Aziridine Ring Opening

Marcelo Siqueira Valle, Raquel Marques Braga*
Instituto de Química, Universidade Estadual de Campinas, P.O. Box 6154, Campinas, SP 13084-971, Brazil
Fax: +55(19)35213023; e-Mail: raquel@iqm.unicamp.br;
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Publikationsverlauf

Received 1 May 2008
Publikationsdatum:
16. Oktober 2008 (online)

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Abstract

Transformation of d-glucitol into its 1,6-diazido derivative allowed its conversion into the polyhydroxylated amino­azepane ring in a one-pot reaction using Ph3P and H2O.