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Planta Med
DOI: 10.1055/a-2283-8147
Original Papers

Storage Conditions Influence the Quality of Ginger – A Stability Study Inspired by Clinical Trials

Barbara Tóth
1   Institute of Pharmacognosy, University of Szeged, Szeged, Hungary
2   Institute of Clinical Pharmacy, University of Szeged, Szeged, Hungary
,
Attila Horváth
1   Institute of Pharmacognosy, University of Szeged, Szeged, Hungary
,
Orsolya Jójártné Laczkovich
3   Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Szeged, Hungary
,
Zsófia Dalma Biró
1   Institute of Pharmacognosy, University of Szeged, Szeged, Hungary
,
Mária Matuz
2   Institute of Clinical Pharmacy, University of Szeged, Szeged, Hungary
,
Dezső Csupor 
1   Institute of Pharmacognosy, University of Szeged, Szeged, Hungary
2   Institute of Clinical Pharmacy, University of Szeged, Szeged, Hungary
4   Institute for Translational Medicine, University of Pécs, Pécs, Hungary
› Author AffiliationsSupported by: Ministry of Innovation and Technology of Hungary TKP2021-EGA-32
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Abstract

Ginger has traditionally been used to treat and prevent nausea and vomiting; however, the results of clinical trials are ambiguous. The efficacy of ginger is attributed to gingerols and their metabolites, shogaols. Since these compounds have different pharmacological profiles, the clinical efficacy of ginger products is largely dependent on their chemical composition. The goal of our study was to examine the stability of ginger, determining the 6-gingerol contents in order to assess the effects of different storage conditions. We have performed a 6-month stability test with dry ginger rhizome samples stored in a constant climate chamber in three different storage containers (uncovered glass container, glass container sealed with rubber stopper, and plastic container). The 6-gingerol contents were measured by HPLC method. The concentration of 6-gingerol decreased in all samples. In the sealed glass container, the decrease in 6-gingerol content was significantly lower than in the unsealed glass container and in the plastic container. These results demonstrate that storage conditions have a significant impact on the quality of ginger, which may also affect efficacy.

Keywords

Ginger - Zingiber officinale - gingerol - HPLC - stability - Zingiberaceae

Supporting Information

    The 6-gingerol contents of the samples are available as supporting information and may be found in the online version of this article.

  • Supporting Information


Publication History

Received: 18 January 2024

Accepted after revision: 07 March 2024

Accepted Manuscript online:
08 March 2024

Article published online:
10 April 2024

© 2024. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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